Clinical trials: Movement Disorders
Parkinson Disease
Music Role in PD Rehabilitation
Neurologic Music Therapy (NMT) sensorimotor techniques are increasingly used to improve spatio-temporal gait parameters and postural stability in the course of Parkinson's Disease and following stroke.
- Trial name
- NCT03434496
- Testing
- Gait Trainer 3
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Parkinson Disease
Efficacy and Tolerability of Sifrol® (Pramipexole) in Patients With Advanced Idiopathic Parkinson's Disease
Assessment of daily maintenance dose of Sifrol®, L-dopa sparing effect, effect on tremor, depression, anhedonia and tolerability
- Trial name
- NCT02248220
- Testing
- Pramipexole
- Volunteers
- 657 people
- Sponsor
- Boehringer Ingelheim
Tourette Syndrome in Adolescence, Tourette Syndrome
Influence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome
Investigators propose a cross-sectional, observational pilot study to examine the contribution of stress, family dynamics, and peer relationships to quality of life (QOL) in adolescents with Tourette syndrome (TS).
- Conditions
- Tourette Syndrome in Adolescence, Tourette Syndrome, Tourette Syndrome in Children
- Trial name
- InSPSCTS (NCT04449003)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Vanderbilt University Medical Center
Tourette Syndrome, Tourette Syndrome in Adolescence
A Study to Explore the Effect of Sepranolone in Tourette Syndrome
The study was an open-label, randomized, multicenter, parallel, Phase 2a study in adolescents and adult patients with Tourette syndrome that aimed to explore the efficacy of Sepranolone as a treatment for Tourette syndrome, by…
- Trial name
- NCT05434546
- Testing
- Sepranolone
- Where
- 2 sites in Denmark
- Volunteers
- 26 people
- Sponsor
- Asarina Pharma
Child Development Disorders, Pervasive
Using Mobile Technology to Reduce Stereotypy
Nearly all children with autism spectrum disorders engage in non-functional repetitive vocal and motor behaviours commonly referred to as stereotypy.
- Trial name
- NCT02124720
- Testing
- iSTIM
- Where
- 3 sites in Canada
- Volunteers
- 39 people
- Sponsor
- Université de Montréal
Malocclusion, Tooth Movement
Additional Palatal Force in Maxillary Canine Distalization
In orthodontic treatment involving extraction of the maxillary first premolars, the canine is distalized into the extraction space using sliding mechanics.
- Trial name
- NCT07862790
- Testing
- Combined buccal and palatal distalizing force, Buccal distalizing force
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Atlas University
Cerebrovascular Accidents
Development of a Refined Version of the Stroke Rehabilitation Assessment of Movement Scale for Stroke Patients
We will employ modern test theory (i.e., Rasch model) to refine the Stroke Rehabilitation Assessment of Movement instrument (STREAM), which will be called the refined version of the STREAM, R-STREAM).
- Trial name
- NCT00173810
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Malocclusion, Angle Class I, Crowding
The Role of Low Level Laser Therapy in Acceleration of Teeth Alignment in Lingual Orthodontic Patients
We will treat patients with class I malocclusion who have moderate crowding (4-6 mm) according to Little's irregularity index and asses the efficacy of low level laser therapy in accelerating orthodontic tooth movement .
- Trial name
- NCT03646942
- Testing
- low level laser therapy, Lingual Orthodontics
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Shoulder Injuries, Musculoskeletal Injury
Shoulder Instability in Children: Muscle Activity and Movement
The aim of this study is to identify factors responsible for recurrent shoulder instability in children. Shoulder instability, i.e.
- Conditions
- Shoulder Injuries, Musculoskeletal Injury, Pediatric ALL, Dislocation, Shoulder
- Trial name
- NCT04311216
- Testing
- 3D movement analysis with surface electromyography
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Infant Development, Infant,Premature
Movement-based Infant Intervention
The objective is to pilot test the effectiveness of an evidence-based intervention to promote positive neurodevelopmental outcomes in infants at risk for developmental delay.
- Conditions
- Infant Development, Infant,Premature, Infant, Very Low Birth Weight, Infant, Small for Gestational Age
- Trial name
- NCT03082313
- Testing
- Movement Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Southern California
Wilson Disease
Study of Zinc for Wilson Disease
OBJECTIVES: I. Establish the safety and efficacy of extended maintenance zinc therapy in 200 patients with Wilson disease. II. Establish further the role of zinc in the prophylactic treatment of presymptomatic patients by…
- Trial name
- NCT00004338
- Testing
- zinc acetate
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Center for Research Resources (NCRR)
Autoimmune Disease, Mental Disorder
Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal Infections
Bacteria carry substances on their surface called antigens. When antigens come into contact with the right kinds of cells in the body an immune reaction is caused.
- Conditions
- Autoimmune Disease, Mental Disorder, Obsessive Compulsive Disorder, Streptococcal Infection
- Trial name
- NCT00001658
- Testing
- Amoxicillin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Mental Health (NIMH)
Huntington Disease
Study of Huntington Patients in Connection With European Huntington's Disease Network (EHDN)
REGISTRY is a multi-centre, multi-national, prospective, observational study of Huntington's disease (HD) with a control group of volunteers.
- Trial name
- NCT01554033
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Parkinson's Disease, Sleep Disorder; Excessive Somnolence
Light Therapy Treatment in Parkinson's Disease Patients With Daytime Somnolence
Study objectives are to determine the efficacy, safety and tolerability of bright light treatment in Parkinson's Disease (PD) patients with daytime sleepiness.
- Trial name
- NCT01338649
- Testing
- Bright Light Treatment (Sun Ray Sunbox SB-558), Dim red light (Sun Ray Sunbox SB-558)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Northwestern University
Movement Disorder
Phenotype/Genotype Correlations in Movement Disorders
The goal of this protocol is to identify families with inherited movement disorders and evaluate disease manifestations to establish an accurate clinical diagnosis by using newest technological advances and investigate the…
- Trial name
- NCT00018889
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy, Infant Development
Associations Between General Movements Assessments and Cognitive Development
High risk infant is defined as infant with a negative history of environmental and biological factors, which can lead to neuromotor development problems.
- Conditions
- Cerebral Palsy, Infant Development, Cognitive Dysfunction, Cognitive Developmental Delay
- Trial name
- GMs (NCT05217056)
- Testing
- measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Inhalation Aromatherapy
Effect of Inhalation Aromatherapy on Anxiety and Depressive Symptoms of Geriatric Patients With Parkinson's Disease
The present study aims to: Investigate the effect of inhalation aromatherapy on anxiety and depressive symptoms of geriatric patients with Parkinson's disease.
- Trial name
- NCT05728177
- Testing
- Inhalation Aromatherapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Sydenham Chorea, Strep Throat
Dopaminergic Receptors in Sydenham's Chorea
Sydenham's chorea (SC) is a post-streptococcal, neuropsychiatric disorder associated with anti-neuronal antibodies. The investigators demonstrated elevated anti-D1-receptor (D1R) and anti-D2-receptor (D2R) antibodies titers…
- Trial name
- NCT04084977
- Testing
- Antibody detection
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Shaare Zedek Medical Center
Citrate Transporter Deficiency, Epilepsy
SLC13A5 Deficiency Natural History Study - Remote Only
SLC13A5 deficiency (Citrate Transporter Disorder, EIEE 25) is a rare genetic disorder with neurodevelopmental delays and seizure onset in the first few days of life.
- Conditions
- Citrate Transporter Deficiency, Epilepsy, Rare Diseases, Movement Disorders
- Trial name
- NCT04681781
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- TESS Research Foundation
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