Clinical trials: Movement Disorders
Upper Extremity Dysfunction
Movement Enhancing Device for Children
The purpose of this study is to assess: 1) how infants move their bodies to explore, play, and solve problems, 2) if this is different in a high-risk group of infants, and 3) if these abilities can be advanced in a high-risk…
- Trial name
- NCT01959581
- Testing
- Movement Enhancing Device
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Parkinson Disease
Comparing the Effectiveness of Shotokan-Karate vs. Tai Chi on Balance and Quality of Life in Parkinson's Disease
The following study will be a comparison of balance and quality of life in Tai Chi training programs and Shotokan-Karate training programs in individuals with Parkinson's Disease.
- Trial name
- NCT03443752
- Testing
- Shotokan-Karate, Tai-Chi
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Parkinson Disease
Effect of Metformin as Add-on Therapy in Levodopa Treated Parkinson's Disease Patients
The goal of this clinical trial is to learn that metformin has effect on motor aspects of daily living and oxidative stress in levodopa treated Parkinson disease patients. Researcher will compare drug metformin to a placebo.
- Trial name
- NCT07055958
- Testing
- Metformin
- Where
- Bangladesh
- Volunteers
- 74 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Tourette's Syndrome
Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome
To evaluate whether supplementing with PS128 can improve the symptoms and quality of life related to Tourette's disease in children.
- Trial name
- NCT04805385
- Testing
- PS128
- Where
- Taiwan
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Wilson Disease, Generalized Epilepsy
Clinical Features and Outcome of Wilson's Disease With Generalized Epilepsy in Chinese Patients
Generalized epilepsy is rarely reported in patients with Wilson disease (WD) and lacks experience in clinical practice. We aim to provide better experience for the diagnosis and treatment for WD patients with epilepsy in the…
- Trial name
- NCT04965571
- Testing
- genetic test
- Where
- China
- Volunteers
- 13 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pain Management, Root Resorption
Photobiomodulation Effect on Vietnamese Orthodontic Patients
Since most orthodontic cases endure for 2 to 3 years or longer, patients are at a high risk of inflammatory root resorption and prolonged orthodontic pain, which is a common and unwanted side effect of their treatment.
- Conditions
- Pain Management, Root Resorption, Orthodontic, Tooth Movement
- Trial name
- NCT07276984
- Testing
- LED device
- Where
- Vietnam
- Volunteers
- 16 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Bimaxillary Protrusion, Class II Div 1 Malocclusion
Discision as Acceleration Method in Canine Retraction in Orthodontics With Aligner and Fixed Appliances in Young Adults a Split Mouth Study
The effectiveness of discision in accelerating orthodontic canine retraction will be evaluated during clear aligner therapy and during conventional fixed orthodontic appliances.
- Trial name
- NCT07920276
- Testing
- Discision
- Where
- 2 sites in Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Neurodegenerative Diseases, Alzheimer Disease
Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study
In this retrospective register study, clinically classified individuals with neurodegenerative disease from the years 2010-2021 will be verified from the clinical records from KUH and Oulu University Hospital (OUH).
- Conditions
- Neurodegenerative Diseases, Alzheimer Disease, Frontotemporal Dementia, Lewy Body Disease
- Trial name
- DEGERWD (NCT06209515)
- Where
- Finland
- Volunteers
- 61,292 people
- Sponsor
- Kuopio University Hospital
Hemiparesis, Cerebral Palsy
The Baby CHAMP Study (Children With Hemiparesis Arm and Movement Project)
The Baby CHAMP Study is a multisite clinical trial funded by the National Institutes of Health that is examining the the use of constraint-induced movement therapy (CIMT) for infants and toddlers as a effective treatment, since…
- Trial name
- The Baby CHAMP (NCT02346825)
- Testing
- Neurorehabilitation therapy with cast, Neurorehabilitation therapy with splint, Neurorehabilitation bimanual
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- Virginia Polytechnic Institute and State University
Parkinson Disease
Conservative Iron Chelation as a Disease-modifying Strategy in Parkinson's Disease
This study evaluates the effect of iron chelation as a therapeutic strategy to slow the progression of Parkinson's disease. Half of participants will receive the deferiprone to 15 mg / kg twice daily morning and evening (30mg /…
- Trial name
- FAIRPARKII (NCT02655315)
- Testing
- Deferiprone
- Where
- 25 sites in Austria, Czechia and 6 more
- Volunteers
- 372 people
- Sponsor
- University Hospital, Lille
Cerebral Palsy Spastic Hemiplegic
Therapeutic Effects of Constraint-Induced Movement Therapy on Young Children With Cerebral Palsy
This study evaluates the therapeutic effects of constraint-induced movement therapy on infants and children with hemiplegic cerebral palsy.
- Trial name
- NCT03858335
- Testing
- Constraint-induced movement therapy
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Samsung Medical Center
Parkinson Disease
Algorithm Guided DBS Programming in Parkinson's Patients
Patients undergoing Deep Brain Stimulation for Parkinson's disease will be subjected to standard of care programming and compared with the algorithm based programming (StimSearch).
- Trial name
- NCT06205043
- Testing
- StimSearch programming algorithm software, Clinician based programming
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Jaslok Hospital and Research Centre
Movement Disorders
Effectiveness of Vojta Therapy in Motor Development of Preterm Children
Justification: Prematurely born children have an increased prevalence of neurodevelopment problems in the first two years. Knowledge regarding the effects of early intervention programs is essential to the follow up of these…
- Trial name
- NCT01838278
- Testing
- Vojta Physiotherapy Method
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Parkinson Disease
A Reminder App for Supporting Adherence to Treatment Goals in Parkinson's Disease
Parkinson's Disease is a progressive condition which affects the nervous system causing tremors, slowed movement and often causes problems with memory and initiation.
- Trial name
- NCT05106985
- Testing
- ApplTree reminder app
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- NHS Greater Glasgow and Clyde
Functional and Motility Related Gastrointestinal Disorders Such as Irritable Bowel Syndrome and Functional Dyspepsia
A Pharmacy-based Study to Learn More About How Well Iberogast Works, How it Affects the Body, How it is Used, and User Satisfaction in Patients With Functional and Motility-related (Stomach and Bowel Movement-related) Gastrointestinal Diseases, Including Irritable Bowel Syndrome
Researchers want to learn more about the day-to-day use of Iberogast in people who have functional and motility-related gastrointestinal (stomach and bowel) diseases.
- Trial name
- NCT04993989
- Testing
- Iberogast (STW5, BAY98-7411)
- Where
- Germany
- Volunteers
- 843 people
- Sponsor
- Bayer
Ideomotor Apraxia
EEG and EMG Analysis of Ideomotor Apraxia
This study will examine how the brain operates during execution and control of voluntary movement and what goes wrong with these processes in disease.
- Trial name
- NCT00024999
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease
Special Survey on Parkinson's Disease Patients Treated Long-term Use of Pramipexole
The survey is conducted to collect safety and effectiveness information on the use of Pramipexole for long time of period in daily clinical settings in Japan.
- Trial name
- NCT00615914
- Where
- 273 sites in Japan
- Volunteers
- 1,645 people
- Sponsor
- Boehringer Ingelheim
Parkinson Disease
Compassionate Use for BIA 28-6156 in Patients With Parkinson's Disease (PD) Who Have a Pathogenic Variant in the GBA1 Gene (GBA-PD) and Completed the ACTIVATE Study
This Program is designed to provide continued access BIA 28-6156, free and compassionately for an eligible patient previously enrolled in the BIA 28-6156-201 (ACTIVATE) clinical study and that had completed the study.
- Trial name
- NCT07522606
- Testing
- BIA 28-6156
- Where
- 36 sites in United States, Italy and 3 more
- Sponsor
- Bial R&D Investments, S.A.
Duchenne Muscular Dystrophy (DMD)
Research on the Relationship Between Scoliosis, Pain, Quality of Life, and Trunk Muscle Compensation Patterns Among Patients with Duchenne Muscular Dystrophy.
Objective: The objective of this observational study is to evaluate and quantify trunk muscle compensatory movement patterns in patients with Duchenne Muscular Dystrophy (DMD) using computer vision technology.
- Trial name
- NCT06755138
- Testing
- Observational Assessment
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Neurodevelopmental Disorders, Autism
Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
There are currently no approved medications for the treatment of anxiety in children and youth with neurodevelopmental disorders (NDDs), both common and rare.
- Conditions
- Neurodevelopmental Disorders, Autism, Autism Spectrum Disorder, Fragile X Syndrome
- Trial name
- CALM (NCT06081348)
- Testing
- Sertraline
- Where
- 7 sites in Canada
- Volunteers
- 130 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
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