Clinical trials: Movement Disorders
Parkinson's Disease
Tele-diagnostics for Remote Parkinson's Monitoring
The purpose of this research study is to design, implement, and clinically assess a portable, user worn system for monitoring Parkinson's disease (PD) motor symptoms.
- Trial name
- NCT01356056
- Testing
- Kinesia HomeView
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Great Lakes NeuroTechnologies Inc.
Motor Neuron Disease
Brain Function in Primary Lateral Sclerosis
This study will examine whether the motor cortex (the part of the brain that controls movement) works properly in patients with primary lateral sclerosis (PLS), a disorder in which voluntary movements are very slow.
- Trial name
- NCT00071435
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
REM Sleep Behavior Disorder
Gut Microbiota in the Progression of Alpha-synucleinopathies
The aim of this study is to correlate baseline gut microbiota features and the progression of neurodegeneration in the established cohort of patients with early Parkinson's disease.
- Trial name
- NCT05353868
- Testing
- No intervention
- Where
- Hong Kong
- Volunteers
- 490 people
- Sponsor
- Chinese University of Hong Kong
Parkinson Disease
New Biomarkers in Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease and its prevalence is expected to double over the next 30 years, making it a leading cause of neurological disability [GBD 2016 Neurology Collaborators…
- Trial name
- NCT05150158
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Schizophrenia, Psychosis
Effects of Rhythmic Auditory Stimulation on Movements in Individuals at Risk for Psychotic Onset and Schizophrenia Patients
The purpose of this research is to examine effects of movement training with the aid of rhythmic auditory stimulation (RAS) on reducing severity of dyskinesia and bradykinesia in at-risk individuals and schizophrenia patients.
- Conditions
- Schizophrenia, Psychosis, Parkinsonism, Dyskinesias
- Trial name
- NCT04553835
- Testing
- Rhythmic auditory stimulation (RAS) for schizophrenia patients, No RAS for schizophrenia patients, RAS for at-risk individuals
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr WANG Shumei
Wilson's Disease
A Registered Cohort Study on Wilson's Disease
The aim of this study is to determine the clinical spectrum and natural progression of Wilson's Disease in a prospective multicenter natural history study, to assess the clinical, genetic, epigenetic features and biomarkers of…
- Trial name
- NCT04012658
- Testing
- No intervention
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Wan-Jin Chen
Parkinson Disease
Action Observation Plus Sonification Therapeutic Protocol
The target of this clinical trial is Freezing of Gait symptom (FoG), and associated falls. The project is aimed to evaluate the effects of an innovative experimental protocol to treat Parkinson (PD) Patients with FoG.
- Trial name
- AOFREEPD (NCT03249155)
- Testing
- AO - plus sonification, CUE - visual and auditory
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Child Obesity, Activity, Motor
Early Years Physical Activity and Movement Skills Intervention: a Feasibility Study
This project aims to test the feasibility of using an existing training course for nursery practitioners (those that care for children aged under 5 years) to improve their ability and confidence to teach fundamental movement…
- Conditions
- Child Obesity, Activity, Motor, Physical Activity
- Trial name
- NCT04868084
- Testing
- Physical literacy in the early years
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Acute Lymphobkastic Leukemia, Medication Adherence
The AYA Oncology Self-care Movement
This trial will test the impact of a social media intervention for improving oral chemotherapy adherence among adolescents and young adults (AYAs) with acute lymphoblastic leukemia.
- Trial name
- #AYAOSM (NCT07724652)
- Testing
- Educational Website, #AYAOSM
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Tourette Syndrome, Tic Disorders
Effectiveness of Behavior Therapy and Psychosocial Therapy for the Treatment of Tourette Syndrome and Chronic Tic Disorder
This study will compare the efficacy of supportive therapy versus habit-reversal therapy for the treatment of Tourette syndrome and chronic tic disorder.
- Trial name
- NCT00231985
- Testing
- Habit reversal therapy, Supportive therapy
- Where
- 3 sites in United States
- Volunteers
- 122 people
- Sponsor
- Massachusetts General Hospital
Writer's Cramp, Dystonias
VTS Sensorimotor Neuromodulation in WC
Writer's cramps (WC) is a focal task-specific upper limb dystonia that significantly impairs handwriting and other manual skills, affecting functionality.
- Trial name
- VTS in WC (NCT07894198)
- Testing
- Vibro-tactile stimulation
- Volunteers
- 10 people
- Sponsor
- Ottawa Hospital Research Institute
Dystonia, Focal
Oral Zinc Supplementation to Enhance Botulinum Neurotoxin Response
Botulinum neurotoxin (BoNT) is injected into muscles for treatment of dystonia. BoNTs are zinc proteases, and their enzymatic effect is reduced in the setting of low zinc.
- Trial name
- NCT05095493
- Testing
- Zinc Acetate
- Volunteers
- 54 people
- Sponsor
- University of Texas Southwestern Medical Center
ALS, Amyotrophic Lateral Sclerosis
NYSCF Scientific Discovery Biobank
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate diverse disease research using cells from the body (such as skin or blood cells) to make stem cells and other types of cells…
- Conditions
- ALS, Amyotrophic Lateral Sclerosis, Alzheimer Disease, Alzheimer Disease, Early Onset
- Trial name
- NCT06203106
- Testing
- Biological Sample Collection
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- New York Stem Cell Foundation Research Institute
Scoliosis Idiopathic
Acute Effects of Self-correcting Movement on the Balance and Spine of Patients With Scoliosis.
The purpose of this study is to evaluate the acute effects of the self-elongation movement on the balance of patients (aged 8-16 years) suffering from adolescent idiopathic scoliosis,
- Trial name
- NCT05039255
- Volunteers
- 35 people
- Sponsor
- University of Pavia
Parkinson Disease
Study of Clozapine for the Treatment of Psychosis in Patients With Idiopathic Parkinson's Disease
OBJECTIVES: I. Determine the efficacy and tolerability of clozapine in ameliorating psychosis in patients with idiopathic Parkinson's disease (PD). II.
- Trial name
- NCT00004826
- Testing
- clozapine
- Volunteers
- 60 people
- Sponsor
- Memorial Hospital of Rhode Island
Infant Development, Sensory Disorder
The Prechtl's General Movement Assessment, Hammersmith Infant Neurological Examination and Sensory Profile-2
In the Neonatal Intensive Care Unit (NICU), infants encounter many sensory stimuli (excessive noise, bright lights, painful medical applications, etc.) that are not present in the uterus.
- Conditions
- Infant Development, Sensory Disorder, Sensory Processing Disorder, Motor Delay
- Trial name
- highrisk (NCT05217199)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
The Aim of the Study Was to Screen Prevalence of Periodic Limb Movements Among Chronic Kidney Disease Patients
Periodic Limb Movements Among Dialysis and Non-dialysis Chronic Kidney Disease Patients
Periodic leg movement disorder is defined as periodic episodes of repetitive limb movements during sleep that mainly occur in the lower limb, including the hips, knees and toes and sometimes affects the upper limb.
- Trial name
- NCT05153616
- Testing
- Polysomnography
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Primary Parkinsonism, Secondary Vascular Parkinson Disease
Application of Machine Learning Method in Validation of Screening Cognitive Test for Parkinsonisms
Based on a prospectively collected data analysis, a new tool, namely CoMDA (Cognition in Movement Disorders Assessment) is developed by merging each item of Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment…
- Conditions
- Primary Parkinsonism, Secondary Vascular Parkinson Disease, Multiple System Atrophy, Supranuclear Palsy, Progressive
- Trial name
- CoMDA-ML-P (NCT04858893)
- Testing
- CoMDA associated with Neural Net 91 classificator
- Where
- Italy
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Parkinson's Disease
KW-6002 to Treat Parkinson's Disease
This study will evaluate the effects of an experimental drug called KW-6002 on Parkinson's disease symptoms and on dyskinesias (involuntary movements) that develop as a result of long-term treatment with levodopa.
- Trial name
- NCT00006337
- Testing
- KW-6002, IV Levodopa
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tourette Syndrome
Pilot Study of the Modified Atkins Diet for Tourette Syndrome
Pharmacotherapy has long been considered the primary approach for tic suppression in Tourette syndrome (TS). Unfortunately, medications are often ineffective and frequently have significant side-effects.
- Trial name
- NCT00952601
- Testing
- Modified Atkins diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
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