Clinical trials: Movement Disorders
Impulsive Behavior, Impulse Disorders
Clinical Response of Impulsivity After Brain Stimulation in Parkinson's Disease
The objective of this prospective observational cohort study is to answer the following clinically important questions: 1. In patients with a pre-operative history of ICBs, what is the likelihood of improvement or deterioration…
- Conditions
- Impulsive Behavior, Impulse Disorders, Gambling, Pathological, Eating, Binge
- Trial name
- CRIPS (NCT04811807)
- Testing
- Subthalamic Nucleaus Deep brain stimulation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King's College London
Dyskinesia, Drug-Induced
Aripiprazole for Neuroleptic-Induced Tardive Dyskinesia
The aim of the present study was to investigate the efficacy of aripiprazole in management of pre-existing neuroleptic-induced tardive dyskinesia
- Trial name
- NCT00837707
- Testing
- aripiprazole
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Taoyuan Psychiatric Center, Ministry of Health and Welfare, Executive Yuan, R.O.C. Taiwan
Dystonic Disorder
Sensory Training to Treat Focal Dystonia
This study will examine the effectiveness of Braille reading as a sensory training program for improving symptoms of focal (localized) dystonia, a movement disorder caused by sustained muscle contractions.
- Trial name
- NCT00006336
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tic Disorder
Teen and Adult Tic TMS Study
This project investigates safety, tolerability, and efficacy signals of accelerated continuous theta burst stimulation (cTBS), a form of inhibitory repetitive transcranial magnetic stimulation (rTMS), for patients with Tourette…
- Trial name
- NCT07839377
- Testing
- cTBS (accelerated continuous theta burst stimulation)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Spinal Muscular Atrophy
Reliability and Validity of the ACTIVE-mini for Quantifying Movement in Infants With Spinal Muscular Atrophy
The purpose of this study is to investigate the measurement properties of the Ability Captured Through Interactive Video Evaluation-mini (ACTIVE-mini) for quantifying movement in infants with Spinal Muscular Atrophy (SMA).
- Trial name
- NCT03808233
- Testing
- ACTIVE mini
- Volunteers
- 25 people
- Sponsor
- University of Texas Southwestern Medical Center
Parkinson's Disease
A Study to Evaluate the Effects of Tyramine in Patients Who Completed the PRESTO Study.
This study is to determine if Tyramine has any side effects on patients receiving 0.5mg, 1mg of Rasagiline or Placebo
- Trial name
- NCT00203125
- Testing
- rasagiline mesylate, tyramine
- Volunteers
- 55 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Malocclusion
The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances
The aim of this study is to determine efficacy of OrthoPulse photobiomodulation on the rate of tooth movement during alignment for Subjects receiving fixed appliance orthodontic treatment.
- Trial name
- NCT03202355
- Testing
- Fixed Appliance Orthodontic Treatment, OrthoPulse™
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Down Syndrome
Infants With Down Syndrome on a Different Surface
This study included infants with Down syndrome who applied to the Faculty of Physical Therapy and Rehabilitation, Developmental and Early Physiotherapy Unit of Hacettepe University.
- Trial name
- NCT04539535
- Testing
- General Movements Assessment on two different surfaces in infants with DS and typically infants on the same day
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stroke, Stroke Rehabilitation
360 Degrees Virtual Reality-based Mirror Therapy for Stroke Patients
The goal of this randomized controlled trial is to compare the effects of 360 degree virtual reality-based mirror therapy (360MT) to traditional mirror therapy (TMT) and conventional physical therapy (control group) on upper…
- Conditions
- Stroke, Stroke Rehabilitation, Mirror Movement Therapy
- Trial name
- NCT05796843
- Testing
- 360 Degrees virtual reality-based mirror therapy, Traditional mirror therapy, Conventional Physical Therapy
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Sahmyook University
Parkinson's Disease
POETRY: Study of Estrogen Replacement Therapy in Postmenopausal Women With Parkinson's Disease
The primary objectives of the POETRY study are to assess the safety and tolerability of estrogen replacement therapy (ERT) in postmenopausal women with Parkinson's disease (PD) and to assess recruitment for a study of ERT in…
- Trial name
- NCT00234676
- Testing
- Premarin ®
- Where
- 6 sites in United States
- Volunteers
- 23 people
- Sponsor
- The Parkinson Study Group
Tic Disorder, Tourette Syndrome
Phase III Study of 5LGr to Treat Tic Disorder
The purpose of this study is to evaluate the effective and safety of 5LGr in pediatric patients with tic disorders.
- Conditions
- Tic Disorder, Tourette Syndrome, Chronic Tic Disorder
- Trial name
- 5LGr (NCT01501695)
- Testing
- 5LGr, tiapride
- Volunteers
- 603 people
- Sponsor
- Tasly Pharmaceuticals, Inc.
Wilson Disease
A Clinical Study to Evaluate the Safety and Efficacy of LY-M003 Injection in Patients With Wilson Disease
Wilson's disease (WD), also known as Wilson's disease, is a rare autosomal recessive metabolic disorder caused by a mutation of the copper transport ATPase β (ATP7B) gene located on the long arm of chromosome 13 (13q14.3).
- Trial name
- WD (NCT06650319)
- Testing
- LY-M003
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Chaohui Yu
Parkinson's Disease
A Long-Term Extension Trial From Late Phase II of SPM 962 in Advanced Parkinson's Disease Patients
The primary objective of this study is to investigate safety of SPM 962 in advanced PD patients in a multi-center, open-label, non-controlled study following once-daily multiple transdermal doses of SPM962 within a range of 4.5…
- Trial name
- NCT01631812
- Testing
- SPM 962
- Where
- 7 sites in Japan
- Volunteers
- 130 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Autistic Disorder
Citalopram for Children With Autism and Repetitive Behavior (STAART Study 1)
This study will determine the efficacy and safety of citalopram compared to placebo in the treatment of children with autism.
- Trial name
- NCT00086645
- Testing
- citalopram hydrobromide
- Where
- 6 sites in United States
- Volunteers
- 149 people
- Sponsor
- Boston University
Primary Dystonia, Hemifacial Spasm
Movement Disorder Survey in East China
Movement disorder involve recurring or constant muscle contractions causing squeezing or twisting movement, such as hemifacial spasm, blepharospasm, cervical dystonias etc.
- Trial name
- MDS (NCT01168388)
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- Sir Run Run Shaw Hospital
Parkinson Disease, Physical Inactivity
Physical Activity in Persons With Parkinson's Disease
Parkinson's disease (PD) is a leading neurodegenerative health condition in Sweden and a public health concern. Although no cure exists, functional independence and participation in society remain top priorities, and can be…
- Trial name
- ActivPARK (NCT06901869)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Tourette Syndrome
Brain Activity Associated With Tics in Patients With Tourette Syndrome
This study will examine brain activity associated with the involuntary urges or uncontrolled movements, called "tics," experienced by people who have Tourette syndrome (TS).
- Trial name
- NCT00141869
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Involuntary Movements
Pattern and Frequency of Non-epileptic Involuntary Movements
We will perform a medical record review of all patients seen in Assiut University hospital, Egypt, to determine the frequency of movement disorders seen, disease characteristics, diagnostic evaluations.
- Trial name
- NCT04083586
- Testing
- All investigations; laboratory and radiological, needed for diagnosis
- Where
- Egypt
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Assiut University
Neurodevelopmental Disorders, Pediatric Sleep Apnea
Ambulatory Polysomnography in Neurodiverse Children: Feasibility, Quality, and Satisfaction
Laboratory polysomnography is the gold standard for objective sleep measurement. With hospital waiting times becoming increasingly long, outpatient polysomnography seems a good solution.
- Conditions
- Neurodevelopmental Disorders, Pediatric Sleep Apnea, Periodic Leg Movements, Excessive, Sleep-Related, Polysomnography
- Trial name
- NCT06966973
- Testing
- Polysomnograpy
- Where
- France
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- UPNOS
Cerebral Palsy, Infant, Premature, Diseases
Associations Between Early Neonatal Neuroimaging, Hammersmith Infant Neurological Examination and General Movements
High risk infant is defined as infant with a negative history of environmental and biological factors, which can lead to neuromotor development problems.
- Conditions
- Cerebral Palsy, Infant, Premature, Diseases, Infant Development, Neurologic Disorder
- Trial name
- highrisk (NCT05217186)
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Kahramanmaras Sutcu Imam University
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