Clinical trials: Movement Disorders
Parkinson's Disease
The Long Term Impact of Initiating Pramipexole Versus Levodopa in Early Parkinson's Disease (CALM-PD Cohort Study)
To determine the long-term consequences (8 years) of initiating patients with Parkinson's disease on either pramipexole or levodopa.
- Trial name
- CALM-PD Cohort (NCT00804479)
- Testing
- No intervention.
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- University of Rochester
ADHD, Iron-deficiency
Impact of Iron Supplementation Treatment on Brain Iron Concentrations
The goal of the present study is to provide novel data to evaluate brain iron concentration as a mediator of the association between iron supplementation treatment and improvement in symptoms of ADHD and RLS in children…
- Conditions
- ADHD, Iron-deficiency, Restless Legs Syndrome, Periodic Limb Movement Sleep Disorder
- Trial name
- NCT04144790
- Testing
- ferrous sulfate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Hemiparesis, Cerebral Palsy
Children With Hemiparesis Arm and Hand Movement Project (CHAMP Study)
What is the CHAMP Study? The CHAMP Study is a multisite clinical trial funded by the National Institutes of Health that is comparing the efficacy of alternative therapies for young children with unilateral spastic cerebral palsy…
- Conditions
- Hemiparesis, Cerebral Palsy, Brain Injury
- Trial name
- CHAMP (NCT01895660)
- Testing
- Variations in Pediatric Constraint-Induced Movement Therapy (P-CIMT) versus usual and customary rehabilitation
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Virginia Polytechnic Institute and State University
Parkinson Disease
Behavior Addictions Improvement in Parkinson Disease's Patients Treated by Subthalamic Stimulation : Long Term Follow-up
Improvement of behavioral addictions in STN-DBS in PD: Long term follow-up
- Trial name
- PDdicted (NCT01705418)
- Volunteers
- 69 people
- Sponsor
- University Hospital, Grenoble
Wilson's Disease
The Individual Therapy for Patients With Wilson's Disease
Based on the genotype characteristics and genotype-phenotype-treatment prognosis data of Chinese WD patients, this study intends to further optimize the treatment regimen of Chinese WD patients and formulate individualized…
- Trial name
- NCT03957720
- Testing
- DMPS, Penicillamine, DMSA
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke
Predicting Independent Walking Ability Using the Simplified Stroke Rehabilitation Assessment of Movement, Berg Balance Scale, Barthel Index for Activities of Daily Living in Individuals Post Stroke
Cohort observational retrospective pilot study by design. The purpose of this study was to determine a cut scores to predict independent ambulation for the Simplified Stroke Rehabilitation Assessment of Movement, Berg Balance…
- Trial name
- NCT05259215
- Testing
- physiotherapy
- Where
- Ukraine
- Volunteers
- 29 people
- Sponsor
- Ukrainian Association of Physical Therapy
Class II Malocclusion
Clinical Effects of Electrical Stimulation on Speeding up Orthodontic Tooth Movement
Thirty two patients requiring extraction of maxillary first premolars and en-masse retraction of upper anterior teeth will participate in the study.
- Trial name
- NCT05302076
- Testing
- Low-intensity electrical current (LIEC), Traditional fixed orthodontic appliance
- Where
- Syria
- Volunteers
- 32 people
- Sponsor
- Damascus University
Inherited Movement Disorders, Spinocerebellar Ataxias
Biomarker Research in Inherited Movement Disorders
Inherited movement disorders are rare conditions, whose cumulative prevalence are in the order of 5-10/100,000 inhabitants, in most cases progressive and can lead to a significant loss of autonomy after one or more decades of…
- Conditions
- Inherited Movement Disorders, Spinocerebellar Ataxias, Hyperkinetic Disorders
- Trial name
- BIOMOV (NCT05034172)
- Testing
- Clinical follow-up
- Where
- France
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Shoulder Impingement Syndrome
The Immediate Effect of Mulligan's Mobilization With Movement on Shoulder Girdle' Pain, Range of Motion and Muscle Activity, in Subjects With Shoulder Impingement Syndrome
The aim of present study was to evaluate the immediate effect of Mulligan's mobilization with movement on shoulder girdle' pain, range of motion (ROM) and muscle activity, in subjects with shoulder impingement syndrome
- Trial name
- NCT06953895
- Testing
- Mulligan's Mobilization With Movement, Active Mobilization
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Cerebral Palsy
Feasibility of Vision-Language Models for Detecting Physical Assistance as an Observable Criterion Defining GMFCS Levels in Children Aged 2 to 6 Years With Cerebral Palsy
The GMFCS sorts children with cerebral palsy into five levels of gross motor function. What mainly separates one level from the next is two things an observer can see: whether another person has to physically help the child move…
- Trial name
- NCT07824531
- Testing
- Vision-language model assessment of movement video
- Where
- 2 sites in South Korea
- Volunteers
- 26 people
- Sponsor
- Samsung Medical Center
Parkinson Disease, Parkinsons Disease With Dementia
A Pilot Study to Explore the Role of Gut Flora in Parkinson's Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding Parkinson's Disease.
- Conditions
- Parkinson Disease, Parkinsons Disease With Dementia, Parkinson-Dementia Syndrome, Parkinson Disease 2
- Trial name
- NCT04148326
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Parkinson's Disease
Motion Immune Magnetic Resonance Imaging (MRI)
The purpose of this study is to evaluate our recently developed MRI reconstruction strategy for producing artifact-free neuro and abdominal MRI data.
- Trial name
- NCT02302521
- Testing
- Multiplex Sensitivity Encoding (MUSE)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Duke University
Bimaxillary Protrusion, Angle Class II, Division 1
Evaluation of Two Approaches of Micro-osteoperforations (MOPs) During Orthodontic Canine Retraction
The aim of this clinical prospective study will be directed to evaluate two approaches of micro-osteoperforations (MOPs) during orthodontic canine retraction.
- Conditions
- Bimaxillary Protrusion, Angle Class II, Division 1, Dental Malocclusions
- Trial name
- NCT04868721
- Testing
- micro-osteoperforations
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Al-Azhar University
Parkinson's Disease
Incidence of Parkinson's Disease Among Veterans
This is a database study. Medical records will be reviewed in order to document a new or pending diagnosis of Parkinson's disease and in order to learn more about the disease process.
- Trial name
- NCT00100438
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Tic Disorders
Acupuncture Treatment in Pediatric Patients With Tic Disorders: A Prospective, Single-Center, Randomized Controlled Trial
This study was conducted to observe the efficacy of Nourishing the vital energy and Regulating the spirit needle technique in the treatment of chronic tic disorder through the Yale Global Tic Severity Scale (YGTSS) and the…
- Trial name
- ATPTD (NCT07071428)
- Testing
- Regular acupuncture, the Nourishing the vital energyand Regulating the spirit needle technique
- Where
- China
- Volunteers
- 76 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Malocclusion
The Use of Clear Aligners With Movement Enhancement Techniques
The purpose of this study is to use clear aligners to measure tooth movement and length of treatment.
- Trial name
- NCT02087163
- Testing
- Movement Enhancement Technique, Clear Aligner
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Malocclusion, Angle Class III
Periodontal Ligament Stress Level and Tooth Movement
Orthodontic treatment requires application of force systems to individual teeth or groups of teeth, which results in a cellular response with periodontal ligament (PDL) and alveolar bone remodeling.
- Trial name
- NCT00099814
- Testing
- Two different loop designs which deliver distinctive forces
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Adolescent Behavior Disorder, Eye Movements
Characterization of Mentalization Profiles Related to Emotional Regulation Among Teenagers With Behavioral Disorders
Behavioral disorders in adolescents are defined by a set of diverse behaviors (such as aggressiveness, agitation, clastic crisis, running away and endangerment) whose common characteristic is the predominance of action/…
- Trial name
- CARMEN (NCT05820581)
- Testing
- Mentalisation
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Wilson Disease, D-Penicillamine
Wilson's Disease Treated With D-Penicillamine: Characterization of Skin Damage Secondary to Treatment by Measuring Skin Elasticity
Wilson's disease is a genetic disorder, resulting from an anomaly present on the ATP7B gene located on chromosome 13, causing a progressive accumulation of copper in various organs such as the liver, nervous system and cornea…
- Conditions
- Wilson Disease, D-Penicillamine, Effect of D-penicilline on Cutaneous Elastity of Wilson's Patient
- Trial name
- WILDERME (NCT06945081)
- Testing
- Preparation of forearm molds with SILFLO® silicone
- Where
- 2 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Malocclusion
The Effect of Ultrasound on Orthodontic Tooth Movement
To study whether or not the Aevo System™ medical device enhances the rate of tooth movement in human subjects who use orthodontic braces.
- Trial name
- NCT01828164
- Testing
- Ultrasound
- Where
- 5 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SmileSonica Inc.
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