Clinical trials: Movement Disorders
Sleep Related Rhythmic Movement Disorder (Disorder)
Vestibular Stimulation Therapy for Rhythmic Movement Disorder
This study aims to a) investigate the feasibility of the detection of episodes of RMD using contactless 3D video analysis and customised analysis software and b) the use of vestibular stimulation as a therapy for childhood…
- Trial name
- NCT03528096
- Testing
- Somnomat B, Sound
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- Swiss Federal Institute of Technology
Movement Disorders
Neurophysiological Studies in Patients With Paroxysmal Hyperkinetic Movement Disorders
This study will use three neurophysiological tests (see below) to determine what areas of the brain are responsible for paroxysmal hyperkinetic movement disorders.
- Trial name
- NCT00056888
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy, Muscle Hypertonia
Hypertonia in Patients With Cerebral Palsy
This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension.
- Trial name
- NCT00123708
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autistic Disorder
Citalopram for Children With Autism and Repetitive Behavior (STAART Study 1)
This study will determine the efficacy and safety of citalopram compared to placebo in the treatment of children with autism.
- Trial name
- NCT00086645
- Testing
- citalopram hydrobromide
- Where
- 6 sites in United States
- Volunteers
- 149 people
- Sponsor
- Boston University
Movement Disorders
Evaluation of Diffusion MRI as a Tool in Planning Deep Brain Stimulation (DBS)
The purpose of this study is to explore the relationship between deep brain stimulation implantation site and DTI (diffusion tensor imaging) derived measures for the region and later compare this to the clinical treatment…
- Trial name
- NCT01975532
- Volunteers
- 13 people
- Sponsor
- University of Aarhus
Tourette's Disorder, Tic Disorder
Safety and Tolerability of Once-daily Oral Aripiprazole in Children and Adolescents With Tourette's Disorder
The goal of the current trial is to determine safety of Once-daily aripiprazole in reducing Total Tic Severity in children and adolescents with Tourette's Disorder.
- Trial name
- NCT01727713
- Testing
- Aripiprazole
- Where
- 33 sites in United States, Canada and 2 more
- Volunteers
- 110 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Tourette's Disorder, Tic Disorder
Study Evaluating the Safety and Efficacy of Fixed-dose Once-daily Oral Aripiprazole in Children and Adolescents With Tourette's Disorder
The goal of the current trial is to determine efficacy and safety of Once-daily aripiprazole in reducing Total Tic Severity in children and adolescents with Tourette's Disorder.
- Trial name
- NCT01727700
- Testing
- Aripiprazole
- Where
- 75 sites in United States, Canada and 7 more
- Volunteers
- 133 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Sydenham Chorea, Post Streptococcal Movement Disorder
Intravenous Immunoglobulins as Effective Treatment in Sydenham's Chorea
Children are at risk of developing an involuntary movement disorder after streptococcal throat infections. Not all children are affected and the severity is individually variable.
- Trial name
- NCT00615797
- Testing
- Intravenous immunoglobulin, standard interventions penicillin VK and haloperidol
- Where
- South Africa
- Volunteers
- 20 people
- Sponsor
- University of Cape Town
Movement Disorder, Learning Disability
Effects of a Task Oriented Intervention With Two Goal-setting Approaches
A randomized trial investigating if effects of a goal-directed task oriented intervention is influenced by who takes the decision and establishes the goal (the child or the parent) and whether establishing a goal per se influence…
- Conditions
- Movement Disorder, Learning Disability, Autism Spectrum Disorder, Children
- Trial name
- NCT02160886
- Testing
- child-goal, parent-goal
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Region Gävleborg
Cerebral Palsy, Weakness
Use of Surface Electromyography Biofeedback to Improve Reaching in Children With Cerebral Palsy
A newly-developed device for biofeedback of surface EMG will be used to either increase or decrease activity in the muscles of children with poor reaching due to cerebral palsy.
- Conditions
- Cerebral Palsy, Weakness, Hypertonia
- Trial name
- NCT00473161
- Testing
- surface EMG biofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
Movement Disorders
Effectiveness of Vojta Therapy in Motor Development of Preterm Children
Justification: Prematurely born children have an increased prevalence of neurodevelopment problems in the first two years. Knowledge regarding the effects of early intervention programs is essential to the follow up of these…
- Trial name
- NCT01838278
- Testing
- Vojta Physiotherapy Method
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Parkinson's Disease
Computer-Based Balance Training for People With Parkinson's Disease
This study will be carried out to determine the effectiveness of in-home computer games played by a person with Parkinson's disease for 50 minutes 3 times a week on measures of standing and walking balance.
- Trial name
- NCT01162226
- Testing
- gait and balance training program
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, San Francisco
Cerebrovascular Disorder, Healthy
Magnetic Resonance Imaging Studies of Motor and Thought Processes
Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation).
- Conditions
- Cerebrovascular Disorder, Healthy, Movement Disorder, Nervous System Disease
- Trial name
- NCT00001361
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alzheimer's Disease, Dementia
Diagnosis and Natural History Study of Patients With Neurological Conditions
The purpose of this study is to improve understanding of neurological conditions. Patients participating in this study will continue receiving medical care, routine laboratory tests, and diagnostics tests (X-rays, CT-scans, and…
- Conditions
- Alzheimer's Disease, Dementia, Movement Disorder, Multiple System Atrophy
- Trial name
- NCT00001549
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Movement Disorder, Myoclonus
Treatment of Cortical Myoclonus With Repetitive Transcranial Magnetic Stimulation
Myoclonus is a condition related to epilepsy of involuntary twitching or jerking of the limbs. The purpose of this study is to determine if stimulation of the brain with magnetic pulses can decrease myoclonus.
- Conditions
- Movement Disorder, Myoclonus, Nervous System Disease
- Trial name
- NCT00001663
- Testing
- Magstim Super Rapid Stimulator
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Movement Disorders, Parkinson Disease
Transcranial Magnetic Stimulation for the Treatment of Parkinson's Disease
The problems in motor activity associated with Parkinson's disease are still poorly understood. Patients with Parkinson's disease often suffer from extremely slow movements (bradykinesia) which result in the inability to perform…
- Trial name
- NCT00001665
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Movement Disorders, Myoclonus
Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases
The purpose of this protocol is to identify families with inherited neurologic conditions, especially movement disorders, to evaluate affected and unaffected individuals clinically, and to obtain blood samples for genetic…
- Conditions
- Movement Disorders, Myoclonus, Nervous System Diseases, Tic Disorders
- Trial name
- NCT00001667
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Demyelinating Disease, Healthy
Magnetic Stimulation of the Human Nervous System
Transcranial Magnetic Stimulation (TMS) is a non-invasive technique to gather information about brain function. It is very useful when studying the areas of the brain related to motor activity (motor cortex, corticospinal tract…
- Conditions
- Demyelinating Disease, Healthy, Lysosomal Storage Disease, Motor Neuron Disease
- Trial name
- NCT00001780
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Movement Disorders, Parkinson Disease
Treatment of Parkinson's Disease With Eliprodil
Patients with Parkinson's disease are missing the chemical neurotransmitter dopamine. This occurs as a result of destructive changes in an area of the brain responsible for making dopamine, the basal ganglia.
- Trial name
- NCT00001929
- Testing
- Eliprodil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Essential Tremor
1-Octanol to Treat Essential Tremor
This study will determine the optimal dose of 1-octanol that will safely reduce tremors in patients with essential tremor-a disorder in which the hands, and sometimes the head, shake involuntarily.
- Trial name
- NCT00016679
- Testing
- 1-Octanol
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)