Clinical trials: Mucosal Inflammation
Radio Dermatitis, Mucositis Oral
Using Red Light Therapy to Ease Skin Side Effects and Mouth Side Effects, in Children and Young People Aged 0 to 16 Years Old, Receiving Radiotherapy
The goal of this interventional study is to see if the daily use of red light therapy called photobiomodulation can help sore skin and sore mouths in children having radiotherapy.
- Conditions
- Radio Dermatitis, Mucositis Oral, Oesophagitis
- Trial name
- RADIANT (NCT07183267)
- Testing
- Photobiomodulation
- Where
- United Kingdom
- Volunteers
- 248 people
- Sponsor
- The Christie NHS Foundation Trust
Oral Mucositis
Oral Care With Propolis in Pediatric Oncology Patients
According to the data from the World Health Organization, approximately 14 million people are diagnosed with cancer every year, and this number is expected to increase further in the next 10 years.
- Trial name
- NCT05400031
- Testing
- propolis
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Izmir Katip Celebi University
Mucositis, Dry Mouth
Effect of Fluoride Varnish and CPP-ACP on Oral and Salivary Symptoms During Chemotherapy
The purpose of this study was to investigate the effect of Fluoride varnish and Casein Phospho-Peptide Amorphous Calcium Phosphate (CPP-ACP) containing paste on oral symptoms and salivary characteristics in patients under…
- Conditions
- Mucositis, Dry Mouth, Infection
- Trial name
- NCT01737307
- Testing
- Fluoride varnish, Oral Hygiene, CPP-ACP
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Azad University of Medical Sciences
Oral Mucositis in Patients Undergoing HSCT
A Phase III Study of Efficacy of Lactobacillus CD2 Lozenges in Preventing High-Dose Chemotherapy Induced Oral Mucositis in Patients Undergoing Myeloablative Hematopoietic Stem Cell Transplantation
The study will be conducted at departments of Medical Oncology and Hematology, All India Institute of Medical Sciences (AIIMS). Patients with various malignancies who are taken up for high dose chemotherapy followed by stem cells…
- Trial name
- mucositis (NCT01797952)
- Testing
- Lactobacillus CD 2
- Where
- India
- Sponsor
- All India Institute of Medical Sciences
Peri-Implantitis
Peri-implantitis in HIV-positive Patients
Objectives: This study aimed to assess the prevalence of peri-implantitis in human im-munodeficiency virus (HIV) -positive patients and the presence of a possible correlation between the immunological profile and serological…
- Trial name
- PERIHIV2 (NCT04829968)
- Testing
- gingival conditions control
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Università Vita-Salute San Raffaele
Oral Mucositis, Chemotherapy Effect
Photobiomodulation in the Prevention and Management of Oral Mucositis in Children
Oral mucositis (OM) is a frequent, debilitating complication in pediatric oncology that impairs quality of life, nutrition, hydration, and treatment adherence.
- Conditions
- Oral Mucositis, Chemotherapy Effect, Pediatric Cancer
- Trial name
- PBMOM-PEDMX (NCT07372443)
- Testing
- Photobiomodulation, bioadhesive gel
- Volunteers
- 49 people
- Sponsor
- Universidad de Guanajuato
Oral Pain, Oral Ulcers
Ethnopharmacological Studies in Oral Medicine
These are ethnomedicine studies of plants used by rural and indigenous peoples for pain and oral inflammation relief.
- Conditions
- Oral Pain, Oral Ulcers, Oral Tumors
- Trial name
- NCT00200837
- Where
- 3 sites in United States, Colombia and 1 more
- Volunteers
- 1,000 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Oral Mucositis
Honey and a Mixture of Honey, Beeswax and Olive Oil-propolis Extract in Treatment of Chemotherapy-induced Oral Mucositis
Although, oral mucositis has been studied for many years, no available treatment has been shown to be effective in preventing or treating mucositis.
- Trial name
- NCT01431729
- Testing
- honey, hope,mucositis
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- mamdouh abdulmaksoud abdulrhman
Allogeneic Stem Cell Transplantation
Xylitol BSI Multisite - Reduction of Bloodstream Infections From Oral Organisms in Pediatric Stem Cell Transplant
Bloodstream infections (BSI) caused by bacteria translocating across injured oral mucosa are a significant cause of morbidity and mortality in patients undergoing stem cell transplantation (SCT).
- Trial name
- NCT05579639
- Testing
- Xylitol
- Where
- 3 sites in United States
- Volunteers
- 256 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cryotherapy Effect
Cryoprotection of Chemotherapy-induced Oral Mucositis After Autologous Stem Cell Transplantation, a Randomized Study
This study evaluates, among study patients with lymphoma or myeloma undergoing autologous SCT, whether cooling oral mucosa with a cooling device compared with ice cubes/crushed ice or ice pop succeeds in reducing the degree of…
- Trial name
- NCT03203733
- Testing
- Cooral™, cryotherapy
- Where
- 5 sites in Norway, Sweden
- Volunteers
- 182 people
- Sponsor
- Uppsala University
Cancer
Evaluation of Oral Morphine Gel in Oral Mucositis Induced by Chemotherapy in Children and Young Adults
Chemotherapy kills tumor cells but can also damage healthy cells and cause significant digestive disorders such as ulcers of the mouth, called mucositis. Mucositis are transient but their intensity may require special measures.
- Trial name
- MorphinOgel (NCT02173756)
- Testing
- morphine gel
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Strasbourg, France
Oral Mucositis
Comparative Efficacy of Rebamipide Gargle And Benzydamine HCL Gargle in Prevention and Management of Chemo- and Radio-therapy-induced Oral Mucositis
evaluate preventive and therapeutic effects of Rebamipide gargle on reducing incidence of oral mucositis in comparison with benzydamine HCL mouthwash.
- Trial name
- NCT04685395
- Testing
- Ribamipide gargle \benzdymine HCL gargel
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Oral Mucositis, Total Body Irradiation
Chlorophyllin for Reducing Oral Mucositis in Total Body Irradiation Prior to Transplant
The goal of this phase II, single-arm interventional clinical trial is to evaluate whether oral sodium copper chlorophyllin (CHL) can reduce the frequency and severity of oral mucositis in patients aged 12-65 years undergoing…
- Conditions
- Oral Mucositis, Total Body Irradiation, Hematological Malignancies, Hematopoietic Stem Cell Transplantation (HSCT)
- Trial name
- ChROMME-TBI (NCT07709195)
- Testing
- Sodium Copper Chlorophyllin
- Where
- India
- Volunteers
- 17 people
- Sponsor
- Tata Memorial Centre
Mucositis
Palifermin for Patients Receiving Hematopoietic Stem Cell Transplantation
The purpose of this study is to compare the efficacy and safety of palifermin on reducing mucositis for patients receiving autologous or allogeneic stem cell transplantation with supportive care.
- Trial name
- NCT02313792
- Testing
- Palifermin
- Volunteers
- 88 people
- Sponsor
- The Catholic University of Korea
Peri-Implantitis and Peri-implant Mucositis
Occurrence of Peri-Implant Complications: A Multifactorial Cross-Sectional Study
Dental implants have become, over recent decades, one of the most effective and predictable therapeutic options for replacing missing teeth.
- Trial name
- NCT07638969
- Testing
- Dental implant
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Graft Vs Host Disease, Oral Mucositis (Ulcerative)
Treatment of Oral Mucositis Using Platelet Rich Fibrin TREATMENT OF ORAL MUCOSITIS USING PRF
Oral mucositis (OM) is an inflammatory mucosal demolition frequently observed during treatments for neoplastic diseases such as chemotherapy or radiation therapy.
- Conditions
- Graft Vs Host Disease, Oral Mucositis (Ulcerative), Mesenchymal Stem Cells
- Trial name
- NCT05018754
- Testing
- TREATMENT OF ORAL MUCOSITIS USING PLATELET-RICH-FIBRIN (PRF)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Rome Tor Vergata
Oral Mucositis, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy
Study of a Copaiba-Based Mouthwash Combined With Low-Level Laser Therapy in the Prevention of Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation
Oral mucositis (OM) one of the most significant acute toxicity of Hematopoietic Stem Cell Transplantation (HSCT). There is already scientific evidence suporting OM the use of: low-level laser therapy (LLLT), cryotherapy (in…
- Conditions
- Oral Mucositis, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Oral Mucositis Due to Chemotherapy, Oral Mucositis in Patients Undergoing HSCT
- Trial name
- NCT07810530
- Testing
- Copaíba
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Mucositis Oral
Effect of Probiotic Use Bifidobacterium Animalis Subsp. Lactis in Peri-implant Mucositis
Peri-implant disease is an inflammatory process of bacterial etiology that can affect the tissues around the implants and can be classified as peri-implant mucositis or peri-implantitis.
- Trial name
- Mucosite prob (NCT04187222)
- Testing
- Mechanical debridements, Bifidobacterium animalis subsp. lactis
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Inflammation, Vasculitis
Analysis of Bronchial Tissue and Fluid in Patients With Wegener's Granulomatosis
This study will collect fluid and tissue samples from the bronchi (air passages to the lungs) of patients with Wegener's granulomatosis for laboratory examination.
- Conditions
- Inflammation, Vasculitis, Wegener's Granulomatosis
- Trial name
- NCT00001541
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Methotrexate Adverse Reaction, Oral Mucositis
Stratification of Oral Ulcers in Rheumatoid Arthritis Patients Kept on Methotrexate
This study included rheumatoid arthritis patients receiving Methotrexate as monotherapy. All eligible patients were subjected to thorough clinical examination and full history to identify oral events.
- Trial name
- NCT04540250
- Testing
- questionnaire
- Volunteers
- 804 people
- Sponsor
- Beni-Suef University