Clinical trials: Multi-Drug Resistant Organisms
E Coli Infection
Multi-Drug Resistant Organism (MDRO): Study of Highly Resistant Escherichia Coli
This is a prospective, observational, multicenter, case-control study.
- Trial name
- SHREC (NCT04574596)
- Testing
- no Intervention
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Ventilator Associated Pneumonia, Multi-antibiotic Resistance
Ventilator Associated Pneumonia by Multi-Drug Resistant Organism
Ventilator-associated pneumonia (VAP) is an infection of the pulmonary parenchyma in patients exposed to invasive mechanical ventilation for at least 48 h and is part of ICU-acquired pneumonia.
- Trial name
- VAP-MDR (NCT05549427)
- Testing
- Ventilation
- Where
- Oman
- Volunteers
- 319 people
- Sponsor
- Sultan Qaboos University
Bacterial Infection, Benign Neoplasm
Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant
This randomized phase III trial studies chlorhexidine gluconate cleansing to see how well it works compared to control cleansing in preventing central line associated bloodstream infection and acquisition of multi-drug resistant…
- Conditions
- Bacterial Infection, Benign Neoplasm, Malignant Neoplasm, Methicillin-Resistant Staphylococcus Aureus Infection
- Trial name
- NCT01817075
- Testing
- Chlorhexidine Gluconate Skin Cleanser, Laboratory Biomarker Analysis, Mild Soap Skin Cleanser
- Where
- 59 sites in United States, Canada and 1 more
- Volunteers
- 177 people
- Sponsor
- Children's Oncology Group
Healthcare Associated Infections, Methicillin Resistant Staphylococcus Aureus
Active Bathing to Eliminate Infection (ABATE Infection) Trial
The ABATE Infection Project is a cluster randomized trial of hospitals to compare two quality improvement strategies to reduce multi-drug resistant organisms and healthcare-associated infections in non-critical care units.
- Conditions
- Healthcare Associated Infections, Methicillin Resistant Staphylococcus Aureus, Multi Drug Resistant Organisms
- Trial name
- ABATE (NCT02063867)
- Testing
- Arm 2: Decolonization
- Where
- 52 sites in United States
- Volunteers
- 53 people
- Sponsor
- University of California, Irvine
Infections Resistant to Multiple Drugs, Bacterial Infections
Multi-Drug Resistant Organism Network
This study is specifically designed to provide observational data which can be used to help in the design of future randomized clinical trials on both therapeutics and diagnostics for MDRO infections.
- Trial name
- MDRO Network (NCT03646227)
- Testing
- Standard of Care
- Where
- 4 sites in United States, Australia and 2 more
- Volunteers
- 6,496 people
- Sponsor
- Duke University
Multi-Drug Resistant Organisms, Late-Onset Sepsis, Neonatal
Using Antibiotics Wisely - An Antimicrobial Stewardship Program
There are significant variations in antimicrobial consumption across Canadian Neonatal Intensive Care Units (NICUs). Inappropriate and overuse of antibiotics can result in antimicrobial resistance and adverse outcomes among…
- Conditions
- Multi-Drug Resistant Organisms, Late-Onset Sepsis, Neonatal, Antimicrobial Resistance
- Trial name
- NCT04388293
- Testing
- Exposure of interest
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- University of British Columbia
Healthcare Associated Infection, Multidrug Resistant Organisms
Ultra Violet-C Light Evaluation as an Adjunct to Removing Multi-Drug Resistant Organisms (UVCLEAR-MDRO)
This study examines the impact of UV-C light disinfection as an adjunct to routine daily and discharge patient room cleaning on patient infection and colonization with hospital associated bacteria.
- Trial name
- UVCLEAR-MDRO (NCT02605499)
- Testing
- UV-C light disinfection
- Volunteers
- 83 people
- Sponsor
- Johns Hopkins University
Severe Acute Malnutrition, Health Care Associated Infection
Prevention of Nosocomial Infections (CleanKids)
While the standardization of treatment protocols for Severe Acute Malnutrition (SAM) has helped to reduce historically high mortality, mortality in inpatient settings remains substantial, likely due to the severity of…
- Conditions
- Severe Acute Malnutrition, Health Care Associated Infection, Multi Drug Resistant Organisms
- Trial name
- CleanKids (NCT03360877)
- Testing
- Health-care associated infection (HCAI)
- Volunteers
- 4,944 people
- Sponsor
- Epicentre
Covid19, Personal Protective Equipment
Rational Use of Personal Protective Equipment During COVID-19 Pandemic
This study aims to improve the personal protective equipment (PPE) used while treating patients with COVID-19, to protect staff and avoid cross-infection of patients.
- Trial name
- RUPERT (NCT04712045)
- Testing
- New PPE, Old PPE
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Oxford