Clinical trials: Multicystic Dysplastic Kidney
Ureteropelvic Junction Obstruction, Chronic Kidney Diseases
The PRO-FUTURE Project
The goal of this observational study is to learn about specific biomarkers of unilateral ureteropelvic junction obstruction (UPJO) in children undergoing surgical intervention for unilateral UPJO compared with controls.
- Trial name
- PRO-FUTURE (NCT06382233)
- Testing
- Identification of Diagnostic Biomarkers
- Where
- 5 sites in Italy
- Volunteers
- 85 people
- Sponsor
- University of Campania Luigi Vanvitelli
UPJ - Ureteropelvic Obstruction
Modified Antegrade Stenting in Laparoscopic Pediatric Pyeloplasty; an Optimized Approach
Background and Rationale For decades, the use of transanastomotic stents following dismembered pyeloplasty has been controversial.
- Trial name
- NCT06697132
- Testing
- laparoscopic dismembered pyeloplasty
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ureteropelvic Junction Obstruction
CTT on Renogram as an Early Marker of Significant Obstruction in Uretero-pelvic Junction Syndrome
Cortical transit time on diuretic renogram as an early marker of significant obstruction in antenatally detected uretero-pelvic junction syndrome
- Trial name
- JUMP (NCT02812212)
- Testing
- ultrasonography, diuretic renography
- Where
- 5 sites in France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Ureteropelvic Junction Obstruction, Postoperative Pain
Ketamine Added to Quadratus Lumborum Block for Pain Relief After Infant Pyeloplasty
This prospective randomized study evaluates the effect of adding ketamine to bupivacaine in ultrasound-guided quadratus lumborum (QL) block for postoperative pain management in infants undergoing open pyeloplasty.
- Trial name
- KETA-QLB (NCT07596810)
- Testing
- Ketamine + Bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Pelvi Ureteric Junction Obstruction or Ureteral Stricture
Buccal Mucosal Graft for the Repair of Iatrogenic Pelviureteric Junction Obstruction or Ureteric Stricture.
Prospective study to evaluate the safety and efficacy of using buccal mucosal graft for repairing complex cases of iatrogenic pelvi ureteric junction obstruction and long segment ureteric stricture disease.
- Trial name
- NCT04503330
- Testing
- buccal mucosal graft to repair iatrogenic PUJO
- Volunteers
- 20 people
- Sponsor
- Cairo University
Ureteropelvic Junction Obstruction, Renal Functional Recovery
Renal SWE as a Predictor After Pediatric Pyeloplasty for UPJO
Ureteropelvic junction obstruction is an important cause of hydronephrosis and potentially reversible renal functional impairment in children.
- Trial name
- UPJO-SWE (NCT07624019)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Beni-Suef University
Pelviureteric Junction Obstruction, Pyeloplasty
Dismembered Pyeloplasty With and Without After Coming Stent
to compare outcome of pyeloplasty in pediatric population less than 6 months in age using an after coming stent versus stentless pyeloplasty.
- Conditions
- Pelviureteric Junction Obstruction, Pyeloplasty, Neonatal Hydronephrosis, Obstructive Uropathy
- Trial name
- NCT02138877
- Testing
- After coming stent after dismembered pyeloplasty, Stentless dismembered pyeloplasty
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Ureteropelvic Junction Obstruction
Long-term Outcome of Retroperitoneoscopic One-trocar-assisted Pyeloplasty: A Single-center and Single-surgeon Experience
Open surgical dismembered pyeloplasty has traditionally been the preferred method for treating ureteropelvic junction obstruction (UPJO), with a success rate exceeding 94%.
- Trial name
- NCT06349161
- Testing
- One-trocar-assisted pyeloplasty
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- National Children's Hospital, Vietnam
Ureteropelvic Junction Obstruction
Indwelling Double-J Ureteral Stent Versus Externalized Modified-Salle Stent for Pyeloplasty
This prospective study, Randomized Trial of Indwelling Double-J Ureteral Stent Versus Externalized Modified-Salle Stent for Pyeloplasty will consist of four steps: 1.) Enrolling subjects in the study and signing the consent form…
- Trial name
- NCT02713633
- Testing
- internal Double-J stents, External Stent
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Rajeev Chaudhry
Nurse-Patient Relations
A Controlled Study of Improved Javelin Side Recumbent Position and Conventional Postural Placement
The Da Vinci surgical robot Xi system assisted laparoscopic pyeloureteroplasty uses the improved javelin side lying position, which can alleviate the unsafe factors of falling from the bed caused by the conventional posture…
- Trial name
- NCT05551442
- Testing
- To explore the comparative study of different positioning methods in robot assisted laparoscopic pyeloplasty., To discuss the comparative study of different position placement methods of renal pelvis ureteroplasty on the Da Vinci robotic Xi platform
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guiyang Maternal and Child Health Care Hospital
Ureteropelvic Junction Obstruction, Hypospadias
Effect of Oxybutynin on Opioid Use After Urologic Surgery in Children
The goal of this clinical trial is to determine whether giving oxybutynin before urologic reconstruction surgery reduces the amount of opioid pain medication needed in children.
- Trial name
- NCT07911137
- Testing
- Oxybutynin
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Calgary
Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital
Ultrasound Localization Microscopy in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
This clinical study aims to non-invasively visualize perfusion and microvascularization, as well as individual glomeruli, using Ultrasound Localization Microscopy (ULM) and CEUS in patients with congenital anomalies of the kidney…
- Conditions
- Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital, Ureteropelvic Junction Obstruction, Hydronephrosis Congenital
- Trial name
- Search_CAKUT (NCT06921733)
- Testing
- Contrast enhanced ultrasound imaging (CEUS) and post processing with ULM
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Obstruction of Pelviureteric Junction
The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine
The investigators propose a prospective blinded randomized control trial (RCT) to assess the efficacy and safety of a simple method of continuous infusion of a local anesthetic, ropivacaine, via a surgical wound to control pain…
- Trial name
- NCT00930046
- Testing
- Ropivacaine wound catheter, Saline wound catheter
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Boston Children's Hospital
Hydronephrosis, Multicystic-dysplastic Kidney
Ambulatory Blood Pressure Measurement in Children With Congenital Urine Flow Obstruction
PURPOSE - HYPOTHESIS: Children with unilateral congenital urine flow impairment, who require surgery, have abnormal 24-hour ambulatory blood pressure measurements.
- Trial name
- NCT00764543
- Testing
- 24-hour ambulatory blood pressure monitor
- Sponsor
- University of Texas Southwestern Medical Center
Multicystic Dysplastic Kidney, Polycystic Kidney Disease
Amnioinfusion for Fetal Renal Failure
The goal of this clinical trial is to learn if serial amnioinfusions can improve the chances of survival for fetuses with severe kidney problems that cause low amniotic fluid (anhydramnios).
- Conditions
- Multicystic Dysplastic Kidney, Polycystic Kidney Disease, Fetal Renal Anomaly, Anhydramnios
- Trial name
- NCT06728228
- Testing
- Amnioinfusion
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Fetal Care Center, PLLC
Hypospadias, Undescended Testis
Visual Guidelines and Tutoring in Pediatric Urological Surgery
The aim of this study is checking impact of visual guidelines (picture book) and tutoring in pediatric urologic surgery
- Conditions
- Hypospadias, Undescended Testis, Hydrocele, Ureteropelvic Junction Stenosis
- Trial name
- NCT02040389
- Testing
- Picture book, Standard preoperative education
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Shaare Zedek Medical Center
Pediatric Urology, Ureteropelvic Junction Obstruction
Pediatric Robotic Versus Open Pyeloplasty
The objective is conduct a pilot randomized controlled trial comparing robotic and open techniques for surgical correction of congenital UPJ obstruction (pyeloplasty) in pediatric patients.
- Trial name
- NCT04884945
- Testing
- Open Pyeloplasty (OP), Robotic-Assisted Laparoscopic Pyeloplasty (RALP)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Indiana University
Disorder of Urinary Stent, Ureteral Spasm
Randomized Trial of NSAID vs Placebo Prior to Ureteral Stent Removal
This study plans to learn more about whether ibuprofen can reduce pain after removal of a ureteral stent more than a placebo. Some patients experience pain after removal of a ureteral stent.
- Conditions
- Disorder of Urinary Stent, Ureteral Spasm, Ureteropelvic Junction Obstruction, Urolithiasis
- Trial name
- NCT02140970
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Colorado, Denver
Pyeloplasty, Ureteropelvic Junction Obstruction
Comparison Between Classic Laparoscopic Dismembered Pyeloplasty and Insitu Spatulation with Pre-Dismembering Ureteropelvic Angle Suturing.
Background and Rationale One of the most challenging steps in laparoscopic pyeloplasty is the ureteral spatulation in addition to the apical suture placement.
- Trial name
- NCT06696508
- Testing
- Insitu Spatulation with Pre-Dismembering Ureteropelvic Angle Suturing during laparoscopic pyeloplasty, Classic Laparoscopic Dismembered Pyeloplasty
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ureteropelvic Junction Obstruction
The Correlation Between Renal Injury and Biomarkers in Pediatric Ureteropelvic Junction Obstruction Patients
Urinary Neutrophil gelatinase associated lipocalin (NGAL) has been recently reported to be related with the degree of hydronephrosis in pediatric ureteropelvic junction obstruction (UPJO) patients.
- Trial name
- NCT01711996
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yonsei University