Clinical trials: Multimodal Imaging
Heart Failure, Diastolic, Multicenter Study
Diagnosis and OutcoMes evaluAtIoN of Multicenter Patients With HFpEF Using Multimodality Imaging
The incidence of Heart failure with preserved ejection fraction (HFpEF) in Heart failure patients increases rapidly. However, the current clinical awareness is insufficient, and the cardiac structural and functional injury are…
- Trial name
- NCT04602338
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Anaplastic Thyroid Cancer
Review of Multimodality Management of Anaplastic Thyroid Cancer
To describe the outcome of patients with anaplastic thyroid cancer treated with hyperfractionated radiotherapy and concomitant chemotherapy
- Trial name
- NCT00280852
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Alberta Health services
Positron-Emission Tomography
The Performance of Multi-tracer Multimodality PET in Lymphoma
Investigating the performance of Multi-tracer Multimodality PET in lymphoma
- Trial name
- NCT05004961
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Cancer Hospital & Institute
Autism
Brain Plasticity of Autism in Response to Early Behavioral Intervention: A Multimodal MRI Study
Autism is a well-recognized neurodevelopmental disorder severely affecting the health of children. While the unclear neurobiological basis of autism and the lack of effective medication, the most commonly used approach for…
- Trial name
- NCT02807766
- Testing
- Behavior modification, Behavior modification and sensory integration training, Behavior modification and applied behavioral analysis
- Where
- 2 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Brain Arteriovenous Malformation
Registry of Multimodality Treatment for Brain Arteriovenous Malformation in Mainland China
This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program.
- Trial name
- MATCH (NCT04572568)
- Testing
- Multi-disciplinary assessment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Ocular Diseases
Ophthalmic Multimodal AI-Assisted Medical Decision-Making
This is a multi-center, retrospective clinical study designed to evaluate the application and effectiveness of an AI-assisted medical decision support system, leveraging multimodal data fusion, in ophthalmic clinical practice.
- Trial name
- NCT06755190
- Testing
- Diagnostic Test: AI-Based Diagnostic and Prognostic Model for Ocular Diseases
- Where
- 5 sites in China, Macau
- Volunteers
- 5,000,000 people
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Depression
Neural and Cognitive Mechanisms of Depression and Anxiety: a Multimodal MRI Study
To explore the neural and cognitive mechanisms of depression (including unipolar depression and Bipolar disorder) and anxiety using multimodal MRI techniques.
- Trial name
- NCT02888509
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Neuroblastoma, Sarcoma
Therapy to Treat Ewing's Sarcoma, Rhabdomyosarcoma or Neuroblastoma
Background: Pediatric solid tumors (Ewing's sarcoma, rhabdomyosarcoma, and neuroblastoma) are often difficult to cure with standard treatment.
- Conditions
- Neuroblastoma, Sarcoma, Rhabdomyosarcoma-Embryonal, Rhabdomyosarcoma- Alveolar
- Trial name
- NCT00923351
- Testing
- Tumor Purged/CD25 Depleted Lymphocytes, Tumor Purged/CD25 Depleted Lymphocytes with Tumor Lysate/KLH Pulsed Dendritic Cell Vaccine, rhIL-7
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Cancer Institute (NCI)
Heart Transplant Rejection
Research on Patients With Heart Transplantation
This trial was a single-center, prospective cohort study.The purpose of this clinical research is to evaluate the accuracy of combining multimodality MR Imaging with circulating exosomal miRNA expression to diagnose acute…
- Trial name
- NCT04921774
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangdong Provincial People's Hospital
Macular Holes, Epiretinal Membrane
Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies
The aim of the study is to identify morphological and functional biomarkers of post-operative recovery after vitreoretinal surgery, using decisional support systems (DSS), based on multimodal big-data analysis by means of machine…
- Conditions
- Macular Holes, Epiretinal Membrane, Retinal Detachment, Macular Dystrophies
- Trial name
- MICAI (NCT05747144)
- Testing
- Biometry, Retinography (Color) + Autofluorescence (AF), OCT B-scan and OCT angiography (OCTA)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Developmental Dyslexia
Prediction and Intervention in Developmental Dyslexia
The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to…
- Trial name
- LEXI (NCT02217696)
- Testing
- Computerized reading training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Ocular Diseases
Ophthalmic AI-Assisted Medical Decision-Making
This is a multi-center, prospective clinical study designed to evaluate the application and effectiveness of an AI-assisted medical decision support system, leveraging multimodal data fusion, in ophthalmic clinical practice.
- Trial name
- NCT06755060
- Testing
- AI-associated strategy
- Where
- 5 sites in China, Macau
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Major Depressive Disorder, Magnetic Resonance Imaging
Multimodal Magnetic Resonance Imaging-based Study of Electroconvulsive Efficacy Prediction in Adolescents With Depression: a Multicenter Prospective Cohort Study
The aim of this project is to investigate the multimodal magnetic resonance brain imaging changes in adolescents with major depressive disorder (MDD) before and after electroconvulsive therapy.
- Conditions
- Major Depressive Disorder, Magnetic Resonance Imaging, Electroconvulsive Therapy
- Trial name
- NCT05889234
- Testing
- Modified Electroconvulsive Therapy, Conventional pharmacotherapy
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Coronary Artery Disease, Coronary Disease
Validation/Evaluation of Multimodal Imaging Combining 3D Ultrasound and Stress Myocardial Scintigraphy in the Diagnosis of Coronary Artery Disease
Our primary goal is to validate a new diagnostic tool for functional coronary artery stenosis that uses multimodal imaging (combining stress echocardiography and stress scintigraphy) in patients with known coronary chest pain.
- Trial name
- NCT01321970
- Testing
- Stress ultrasound, Scintigraphy, Coronary angiography
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Lymphoma, Hodgkin
MELT - MRI Evaluation of Lymphoma Treatment
Patients who are newly diagnosed with Hodgkin's lymphoma will undergo disease staging at diagnosis and initial treatment response assessment.
- Trial name
- MELT (NCT01459224)
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- University College, London
Digestive Diseases, Radiology
AI-Driven Multimodal Imaging Integration for Diagnosis and Prognostication of Digestive System Diseases
The goal of this observational, retrospective and prospective study is to develop a noninvasive disease assessment system by leveraging artificial intelligence (AI) to comprehensively analyze multi-modal imaging features…
- Conditions
- Digestive Diseases, Radiology, AI (Artificial Intelligence), Imaging
- Trial name
- NCT07087418
- Testing
- Virtual endoscopy model-assisted diagnosis
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Breast Cancer Invasive
Intra-operative Detection of Positive Margins and Lymph Nodes in Breast Surgery
In this project, the investigators will develop novel optical coherence tomography (OCT)-Raman spectroscopy and autofluorescence (AF)-Raman spectroscopy systems based on a selective sampling approach optimised for high-resolution…
- Trial name
- NCT06977698
- Testing
- OCT-Raman, AF-Raman
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Nottingham
Infantile Hemangiomas
Ontogeny of Infantile Hemangiomas With Skin Imaging Modalities
A combined set of quantitative skin imaging methods will quantitatively describe the natural ontogeny and the response to standard treatments over time in patients with infantile hemangiomas.
- Trial name
- NCT02061735
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder
Understanding the Mechanisms of Autism : an MRI and Social Cognition Study
The main goal of this study is to investigate anatomo-functional brain abnormalities associated with autism spectrum disorders using a multimodal brain imaging approach, as well as its links to social cognition difficulties…
- Trial name
- ECLAT (NCT06334588)
- Testing
- MRI, Eye-tracking, Clinical Scales
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pancreatic Ductal Adenocarcinoma
Radiomics Based on Multimodal Imaging in Predicting Staging and Prognosis of Pancreatic Cancer
Retrospectively analyzed radiomics features of pancreatic ductal adenocarcinoma to predict staging and prognosis
- Trial name
- NCT04954378
- Testing
- radiomics
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital