Clinical trials: Multimodal Imaging
Autism Spectrum Disorder (ASD)
Brain Stimulation and Sensory Integration in Children With ASD
The goal of this clinical trial is to find out if brain stimulation can help improve sensory integration in children ages 6 to 12 with autism spectrum disorder (ASD).
- Trial name
- NCT07182331
- Testing
- Continuous Theta Burst Stimulation to Bilateral DLPFC
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Neurolab Plus
ADHD - Combined Type
Multimodal Brain Imaging of the Neural Effects of Methylphenidate in Patients With ADHD
The investigators' goal is to develop neuroimaging biomarkers to predict response to treatment with methylphenidate, which then can be used in the development of novel pharmacological treatments for…
- Trial name
- NCT04781972
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Movement Disorders
Multimodal MR Imaging Study on ET and PD Patients Subjected With MRgFUS Thalamotomy
The technological advance of magnetic resonance-guided focused ultrasound (MRgFUS) has once again brought lesion therapy back to the clinical frontline for the treatment of movement disorder.
- Trial name
- NCT05623644
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Amyloidosis Cardiac
Multimodality Cardiac Imaging for Disease Progression in ATTR-CM
The goal of this clinical trial is to investigate whether new imaging techniques can help us to better understand the cardiac amyloidosis.
- Trial name
- FAPI-ATTR (NCT07112066)
- Testing
- FAPI tracer
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Dominik Benz
Anaplastic Thyroid Cancer
Review of Multimodality Management of Anaplastic Thyroid Cancer
To describe the outcome of patients with anaplastic thyroid cancer treated with hyperfractionated radiotherapy and concomitant chemotherapy
- Trial name
- NCT00280852
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Alberta Health services
Heart Function, Quality of Life
Functional and Clinical Benefits of PCI in Patients With CTO
The purpose of this study is to compare the diagnostic accuracy of hybrid imaging combining CTCA with low-dose stress-only SPECT vs.
- Trial name
- NCT01254253
- Testing
- Percutaneous coronary intervention, PCI
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital
Keloid
Multimodal Ultrasound Imaging Assessment on Keloid
Skin keloids are common dermatological conditions that can lead to physical limitations, functional impairments, and deformities.
- Trial name
- NCT06034587
- Testing
- multimodal ultrasound, radioisotope applicator therapy
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Chongqing Medical University
Coronary Artery Disease, Coronary Disease
Validation/Evaluation of Multimodal Imaging Combining 3D Ultrasound and Stress Myocardial Scintigraphy in the Diagnosis of Coronary Artery Disease
Our primary goal is to validate a new diagnostic tool for functional coronary artery stenosis that uses multimodal imaging (combining stress echocardiography and stress scintigraphy) in patients with known coronary chest pain.
- Trial name
- NCT01321970
- Testing
- Stress ultrasound, Scintigraphy, Coronary angiography
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Non-ischemic Cardiomyopathy
Non-ischemic Cardiomyopathy Registry, Biobank and Imaging Data Repository
The main goal of CaNICM is to create a central database that includes a biobank and an imaging data repository for patients with non-ischemic cardiomyopathy (NICM), as well as for at-risk family members.
- Trial name
- CaNICM (NCT07110818)
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- Montreal Heart Institute
Anorexia Nervosa
Serotonin Role on Brain Circuits Involved in Food Avoidance in Anorexia Nervosa
Serotoninergic activity in brain structures involved in food control and avoidance, such as the basal ganglia, is poorly understood in Anorexia Nervosa.
- Trial name
- SEVIALANO (NCT05155280)
- Testing
- PET imaging using [11C]DASB radioligand., Eye Tracker
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
ADHD
Multimodal Magnetic Resonance Imaging Study on the Neural Mechanisms of Remission in Children With ADHD
Attention-deficit/hyperactivity disorder(ADHD) is highly prevalent among children and adolescents and often associated with poor long-term outcomes in adulthood. it is thus a serious public health problem.
- Trial name
- NCT05229627
- Testing
- MPH, ATX
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital
Psychosis
Trajectories of Treatment Response as Window Into the Heterogeneity of Psychosis: a Longitudinal Multimodal Imaging Study
Psychosis is a heterogeneous disorder and present treatment only works for a limited number of patients. In order to identify new therapeutic targets, this study will longitudinally characterize the underlying pathologies in…
- Trial name
- NCT03442101
- Testing
- Patients with psychosis will be treated with known antipsychotic medication
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- University of Alabama at Birmingham
Depression
Neural and Cognitive Mechanisms of Depression and Anxiety: a Multimodal MRI Study
To explore the neural and cognitive mechanisms of depression (including unipolar depression and Bipolar disorder) and anxiety using multimodal MRI techniques.
- Trial name
- NCT02888509
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Head and Neck Cancer
Chemotherapy Followed by Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Locally Advanced Head And Neck Cancer
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00544414
- Testing
- cisplatin, docetaxel, fluorouracil
- Volunteers
- 31 people
- Sponsor
- City of Hope Medical Center
ADHD
Multimodal Brain Imaging of Methylphenidate in Children and Adolescents With ADHD
The goal of this proposal is to develop brain imaging tools to measure the effects of methylphenidate in children and adolescents with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT06077669
- Testing
- Methylphenidate
- Where
- United States
- Sponsor
- Johns Hopkins University
Healthy
Brain Maturation and Sleep
In this study, the investigator evaluates whether there are age-specific diurnal changes in markers of cortical plasticity in children, adolescents and adults.
- Trial name
- BMS (NCT02685891)
- Testing
- Playing tones during deep sleep
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Chronic Respiratory Failure, Non-invasive Ventilation
Improving Chronic Nocturnal Noninvasive Ventilation: a Multimodality Approach
The aim of the data collection is to create an advanced reliable method to remotely monitor patient on chronic home non-invasive ventilation (NIV), both regarding ventilatory efficacy and patient comfort, both in the hospital and…
- Trial name
- NOCTIVENT (NCT05756387)
- Testing
- Non-invasive ventilation
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- University Medical Center Groningen
Cancer
AI-Augmented Diagnostic Assessment With ENLIGHT Versus Independent Pathologist Review
This study will evaluate whether artificial intelligence (AI) can enhance clinicians' accuracy, efficiency, and confidence in distinguishing lung adenocarcinoma (LUAD) from lung squamous cell carcinoma (LUSC) and kidney renal…
- Trial name
- ENLIGHT (NCT07741058)
- Testing
- Unaided Review First, Then AI as Double-Check, Then AI as First-Look., Unaided Review First, Then AI as First-Look, Then AI as Double-Check., AI as Double-Check First, Then AI as First-Look, Then Unaided Review.
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Arterial Switch Operation
Multimodal Imaging Evaluation and Prognostic Analysis of Participants After Arterial Switch Operation
The aims of this study are to 1. Identify the early and midterm outcomes in terms of mortality and reoperation of the arterial switch operation (ASO). 2.
- Trial name
- NCT04980339
- Volunteers
- 1,000 people
- Sponsor
- Xie Mingxing
Acute Coronary Syndrome (ACS)
PROSPECT II & PROSPECT ABSORB - an Integrated Natural History Study and Randomized Trial.
The present study has two components, an overall prospective observational study using multimodality imaging (PROSPECT II) that will examine the natural history of patients with unstable atherosclerotic coronary artery disease…
- Trial name
- P2 (NCT02171065)
- Testing
- ABSORB BVS
- Where
- Sweden
- Volunteers
- 902 people
- Sponsor
- Uppsala University