Clinical trials: Multiple
Colorectal Surgical Procedures
A Study of the ECHELON Contour Curved Cutter Stapler Device in Colorectal Procedures
The purpose of this study is to prospectively generate device-specific clinical data related to the performance of Echelon Contour per its instructions for use (IFU).
- Trial name
- NCT05133141
- Testing
- Echelon Contour
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Ethicon Endo-Surgery
Abdominal Wall Defect, Ventral Hernia
Clinical Study on the Safety of SAFIL® MESH
Observational, Retrospective, Multi-center Clinical Study on the Safety of SAFIL® MESH in Patients Undergoing Reinforcement of Soft Tissues After Abdominal Wall Surgery or Other Fascial Defects
- Conditions
- Abdominal Wall Defect, Ventral Hernia, Abdominal Hernia, Fascial Hernia
- Trial name
- SAFIL_MESH (NCT04947202)
- Testing
- Hernioplasty
- Where
- 2 sites in Spain
- Volunteers
- 152 people
- Sponsor
- Aesculap AG
Pregnancy, Gestational Diabetes
Behavior of Biomarkers During Pregnancy and Lactation Through a Biological Multi-paradigm Model: BECOME Study Protocol
Background Despite of advances in research, at the moment, various points related to the physiology of gestation and the etiology of severe diseases that can be developed in the course of it remain unknown.
- Conditions
- Pregnancy, Gestational Diabetes, Hypertension, Obesity
- Trial name
- BECOME (NCT02811172)
- Testing
- BEhavior of biomarkers during pregnanCy and lactatiOn
- Where
- Spain
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Kidney Neoplasms, Neoplasm Metastasis
A Phase I Study of Continuous Intravenous Infusion of PSC 833 and Vinblastine in Patients With Metastatic Renal Cancer
Bolus PSC 833 is administered on Day 1 simultaneously with initiation of 24 hour continuous infusion of PSC 833, followed by another continuous infusion lasting an additional 6 days.
- Trial name
- NCT00001570
- Testing
- PSC 833, vinblastine
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- National Cancer Institute (NCI)
Chronic Lymphocytic Leukemia, Graft vs Host Disease
The Role of Cyclosporine in Blood Cell Transplants With T-Cell Add-Back for Blood Cancers
Cancers of the blood, sometimes referred to as hematologic malignancies, are disorders of bone marrow cells that lead to the failure of the normal function of bone marrow and the uncontrolled growth of cancerous cells in the bone…
- Conditions
- Chronic Lymphocytic Leukemia, Graft vs Host Disease, Hematologic Neoplasm, Multiple Myeloma
- Trial name
- NCT00001873
- Testing
- Isolex 300i plus MoAbs
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Influenza
A Study of Oseltamivir (Tamiflu) for the Seasonal Prophylaxis of Influenza in Immunocompromised Participants
This 2 arm study will evaluate the efficacy and safety of oseltamivir in the seasonal prophylaxis of influenza in immunocompromised participants (as represented by transplant recipients).
- Trial name
- NCT00412737
- Testing
- Oseltamivir
- Where
- 78 sites in United States, Belgium and 12 more
- Volunteers
- 477 people
- Sponsor
- Hoffmann-La Roche
Juvenile Idiopathic Arthritis (JIA)
Toward Personalized Medicine to Guide Drug Withdrawal in Children with Juvenile Idiopathic Arthritis in Clinical Remission
Biologic therapies made clinical remission an achievable goal for most juvenile idiopathic arthritis (JIA) patients. Nevertheless, antirheumatic drugs have side effects and are costly.
- Trial name
- Re-JIA (NCT06618937)
- Testing
- Treatment medication withdrawal strategy
- Where
- Italy
- Volunteers
- 166 people
- Sponsor
- Istituto Giannina Gaslini
Growth
A Clinical Study to Investigate the Effects of an Infant Formula Containing Partially Hydrolysed Proteins on Growth, Safety and Tolerance in Healthy Term Infants
It is universally accepted that the best nutrition for a new-born infant is breast milk. Breast milk provides a complete set of nutrients to support growth and development of children in early life, including components that have…
- Trial name
- TENUTO (NCT03062761)
- Testing
- Infant Formula with prebiotics, Standard Infant Formula
- Where
- 15 sites in Finland, France and 4 more
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Nutricia Research
Connective Tissue Disease, Dissecting Aneurysm
Study of Heritable Connective Tissue Disorders
The purposes of this study are to identify the genes responsible for inherited connective tissue disorders and learn about the range of medical problems they cause.
- Conditions
- Connective Tissue Disease, Dissecting Aneurysm, Ehlers Danlos Syndrome, Marfan Syndrome
- Trial name
- NCT00001641
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Congenital Heart Disease in Children
Cardiac Simulator for Surgical Planning
The goal of this clinical trial is to learn if a computer software program (cardiac simulator) for surgical planning will lead to improvements in patient care by decreasing the incidence of unsuccessful interventions and…
- Trial name
- NCT06373705
- Testing
- Cardiac simulator
- Volunteers
- 275 people
- Sponsor
- Stanford University
Birth Defect, Newborn; Fit
The Pilot Study of High-throughput Sequencing in Neonatal Birth Defects
In China, birth defects can reach as high as 5.6%, about 900,000 new cases of birth defects are added each year, making it the second cause of death for infants, with a total death rate of 19.1%.
- Conditions
- Birth Defect, Newborn; Fit, Genetic Diseases, Multiple Malformation
- Trial name
- NCT03984266
- Testing
- NGS panel
- Where
- China
- Volunteers
- 3,423 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Down Syndrome
Effect of Core Stability Exercises and Balance Training in Postural Control Among Down Syndrome
Children with Down syndrome often present with problems of posture \& balance and mobility. Balance training is an important component of physical activity interventions, with growing evidence that it can be beneficial for…
- Trial name
- NCT04818437
- Testing
- BALANCE TRAINING, CORE STABILITY EXERCISES
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Respiratory Syncytial Virus Infections, Virus Diseases
A Study to Assess the Pharmacokinetics, Safety, and Tolerability of Multiple Doses of Orally Administered JNJ-53718678 in Infants Hospitalized With Respiratory Syncytial Virus (RSV) Infection
The purpose of this study is to evaluate pharmacokinetics, safety, tolerability, antiviral activity, and impact on the clinical course of Respiratory Syncytial Virus (RSV) infection after multiple oral doses of JNJ-53718678 at…
- Trial name
- NCT02593851
- Testing
- JNJ-53718678
- Where
- 39 sites in United States, Argentina and 8 more
- Volunteers
- 45 people
- Sponsor
- Janssen Sciences Ireland UC
Prostate Cancer
Prostate Cancer Localization With a Multiparametric Magnetic Resonance (MR) Approach
The primary objective of this prospective multi-centre study is to prove the diagnostic accuracy of in vivo 3T multi-modality Magnetic Resonance Imaging (high resolution T2-weighted MRI, DCE-MRI, MRSI and DWI techniques) in…
- Trial name
- PCa-MAP (NCT01138527)
- Testing
- MRI examination
- Where
- 9 sites in United States, Austria and 6 more
- Volunteers
- 148 people
- Sponsor
- Radboud University Medical Center
Ring 14
Multi-Dimensional Genomic Dissection of Ring Chromosome 14 Syndrome
MD-RING will explore the hypothesis that position effects and TAD alterations act as an unprecedented pathomechanism in r(14)S. This will contribute to a better understanding of genotype-to-phenotype correlations, creating an…
- Trial name
- NCT06813469
- Testing
- LRS analysis
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Lower Urinary Track Symptoms, Benign Prostate Obstruction (BPO)
Outcome and Patient Experiences After Transurethral Resection and Bipolar Enucleation of the Prostate - a Multi-center, Randomized Controlled Trial.
In this randomized controlled trial, we will evaluate if bipolar enucleation of the prostate (BEEP) is associated with better urinary voiding outcome than transurethral resection (TURP) in men with enlarged prostate referred to…
- Trial name
- NCT07562386
- Testing
- Transurethral resection of the prostate., Bipolar enucleation of the prostate
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset Innlandet HF
Crohn's Disease
An Efficacy and Safety Study of Omega-3 Free Fatty Acids (Epanova™) for the Maintenance of Symptomatic Remission in Subjects With Crohn's Disease
The purpose of this study is to see if Epanova™ is able to maintain the symptomatic remission in subjects with Crohn's Disease who are responding to steroid induction therapy.
- Trial name
- NCT00074542
- Testing
- Epanova™ (Omega-3 Free Fatty Acids)
- Where
- 31 sites in United States, Canada
- Volunteers
- 364 people
- Sponsor
- Tillotts Pharma AG
Down Syndrome
Effects of Orofacial Therapy and Therapeutic Yoga in Children With Down Syndrome
The study aims to compare the effects of orofacial therapy and therapeutic yoga on swallowing, sleep habits, and quality of life in children with Down syndrome.
- Trial name
- NCT06352151
- Testing
- Routine Physiotherapy Group, Orofacial Treatment Group, Therapeutic Yoga Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hasan Kalyoncu University
Hypertension, Heart Failure
Regulatory Nebilet PMS
An open label, multi-centre, non-interventional post-marketing surveillance (PMS) to monitor the safety and effectiveness of Nebivolol administered in Korean patients according to the prescribing information
- Trial name
- Nebilet PMS (NCT01077661)
- Testing
- Nebivolol
- Where
- South Korea
- Volunteers
- 743 people
- Sponsor
- GlaxoSmithKline
Shoulder Instability
Circumferential Lesions of the Glenoid Labrum
Objective: Symptomatic pan-labral or circumferential (360 degree) tears of the glenohumeral labrum are an uncommon injury. The purpose of this study is to report the prospective surgical results of circumferential lesions of the…
- Trial name
- NCT00849927
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Society of Military Orthopedic Surgeons
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