Clinical trials: Multiple Trauma/Injuries
Warts
Randomized Controlled Clinical Trial of Hyperthermia and Hydrogen Peroxide 3% in the Treatment of Cutaneous Warts
Hyperthermia treatment (hyperthermia) refers to treating diseases with temperature (39-45 ° C) beyond normal body temperature,. It has been reported that local warming at 44 ° C is able to effectively mobilize the body's immunity…
- Trial name
- NCT06812065
- Testing
- Hydrogen Peroxide 3 % Topical Solution, Local Hyperthermia at 44℃
- Where
- 2 sites in China
- Volunteers
- 300 people
- Sponsor
- First Hospital of China Medical University
Brachial Plexus Palsy Due to Birth Trauma, Injury
Non-Anesthetized Plexus Technique for Infant (BPBP) MRI Evaluation
The investigators are studying the ability of a novel rapid magnetic resonance imaging (MRI) protocol to provide more accurate and earlier information about whether an infant with brachial plexus birth palsy will require nerve…
- Conditions
- Brachial Plexus Palsy Due to Birth Trauma, Injury, Newborn
- Trial name
- NAPTIME (NCT03560999)
- Where
- 3 sites in United States
- Volunteers
- 102 people
- Sponsor
- Shriners Hospitals for Children
Trauma, Multiple, Trauma
Swiss Trauma Registry
The Swiss Conference of Cantonal Health Directors has transferred the planning of highly specialized medicine to a specialized body under the direction of the Swiss Academy of Sciences.
- Trial name
- NCT03526029
- Where
- 12 sites in Switzerland
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Head Trauma, Polytrauma
Comparative Study for the Validity of Various Severity Scoring System
Scoring systems for use in intensive care unit (ICU) patients have been introduced and developed over the last 30 years. They allow an assessment of the severity of disease and provide an estimate of in-hospital mortality
- Conditions
- Head Trauma, Polytrauma, Pre-Eclampsia, Sepsis
- Trial name
- NCT04683094
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital
Musculoskeletal Injury, Pediatrics
Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children
The TOP-MAP pilot trial has multiple goals. The first goal of this pilot clinical trial is to find out if it will be possible to carry out a study at multiple pediatric emergency department sites (Peds ED) comparing Non-Steroidal…
- Conditions
- Musculoskeletal Injury, Pediatrics, Sprain and Strain of Ankle, Sprain Knee
- Trial name
- TOP-MAP (NCT07145645)
- Testing
- Voltaren Topical Gel, Ibuprofen Oral Suspension 100 mg/5mL, ORA-Blend Oral Suspension
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Acute Kidney Injury, Nephrotoxicity
Assessment of Urinary Neutrophil Gelatinase-Associated Lipocalin to Predict AKI in the NICU
Nephrotoxic medication (NTMx) exposure is one of the most commonly cited causes of acute kidney injury (AKI) in hospitalized children, and is the primary cause of AKI in 16% of cases.
- Conditions
- Acute Kidney Injury, Nephrotoxicity, Neonatal
- Trial name
- NCT04354467
- Testing
- urine neutrophil gelatinase -associated lipocalin
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- University of Alabama at Birmingham
Sport Injury
Intelligent Sports Injury Prevention and Training System
Sports injuries are a very important issue for baseball players. Previous studies have found that the incidence of sports injuries faced by baseball players is continuously increasing.
- Trial name
- NCT05644704
- Testing
- Lower extremity and core muscle training
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Trauma Exposure, Trauma
Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress
The goal of this clinical trial is to compare the effectiveness of trauma-focused therapies for improving mental health symptoms and daily functioning in youth with chronic medical conditions who have experienced psychological…
- Conditions
- Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning
- Trial name
- NCT07483333
- Testing
- Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Anthony Vesco
Lennox Gastaut Syndrome, Dravet Syndrome
Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution
This study will monitor for potential chronic liver injury and liver fibrosis, in participants treated with cannabidiol oral solution.
- Conditions
- Lennox Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex
- Trial name
- NCT05044819
- Testing
- Cannabidiol
- Where
- 26 sites in United States
- Volunteers
- 154 people
- Sponsor
- Jazz Pharmaceuticals
Traumatic Brain Injury
Comparative Effectiveness of Intervention in Multi-level Hospitals for Acute Traumatic Brain Injury(Metric-TBI)
A prospective, multicenter, observational cohort study is designed to compare the effectiveness of intervention in multi-grade hospitals for acute traumatic brain injury and to optimize clinical outcomes.
- Trial name
- NCT06429774
- Testing
- Neurological function, Mental State, cognitive function, and life quality assessment, Peripheral blood test
- Where
- 64 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Sports Physical Therapy, Multi-Tasking Behavior
A New Dual Task Test Method for Football Players
Multitasking (Dual Task) is a measurement method to evaluate cognitive ability to execute multiple functions at the same time. To perform this test, while participant/patient performing a main skill (for example, walking), a…
- Conditions
- Sports Physical Therapy, Multi-Tasking Behavior, ACL Injury, Kinesiophobia
- Trial name
- NCT05218993
- Testing
- A new dual-task measurement method with images, A new dual-task measurement method with cards
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Fractures, Musculoskeletal
Enhancing Diagnostic Accuracy in Fracture Identification on Musculoskeletal Radiographs Using Deep Learning
This retrospective study aims to evaluate the effectiveness of artificial intelligence (AI) in identifying fractures on musculoskeletal X-rays.
- Trial name
- NCT06644391
- Testing
- Carebot AI Bones
- Where
- Czechia
- Volunteers
- 600 people
- Sponsor
- Carebot s.r.o.
Shoulder Dislocation, Bone Loss
Latarjet vs Anatomic Glenoid Reconstruction
Anterior shoulder dislocations occur when the humeral head translates anterior to the glenoid cause pain, stiffness, and glenoid bone loss. If left untreated, the risk of recurrence can be up to or greater than 90%.
- Conditions
- Shoulder Dislocation, Bone Loss, Arthroscopy
- Trial name
- NCT05658289
- Testing
- Coracoid Transfer, Distal Tibia Allograft with Bankart repair
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Trauma, Tumor
Patient Outcomes Evaluation of the EBI Vuelock™ Anterior Cervical Plate System
To prospectively collect radiographic and outcome data on patients who are having cervical spine fusion surgery with the VueLock™ Anterior Cervical Plate System
- Conditions
- Trauma, Tumor, Pseudarthrosis, Scoliosis
- Trial name
- VueLock (NCT00726128)
- Testing
- VueLock™ Anterior Cervical Plate
- Where
- 4 sites in United States
- Volunteers
- 371 people
- Sponsor
- Zimmer Biomet
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Domestic Violence, PTSD
'Effectively Intervening in Traumatized Parents and Young Children After Structural Domestic Violence: A Multiple Baseline Analysis'
The goal of this study is to evaluate the effectiveness of an individualized treatment trajectory in which the order of trauma therapy for the parent (Eye movement desensitization and reprocessing (EMDR) therapy), trauma therapy…
- Trial name
- NCT06065865
- Testing
- Guidance document
- Where
- Netherlands
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden
Wellbeing, Mental Health
Many Trauma-affected Youth Face Long Waits for Therapy, Worsening Stress, and Avoidance. CISS, a 90-minute Session Based on Stanford's Cue-Centered Therapy, Offers Coping Tools and Psychoeducation During This Gap. This Pilot Tests CISS's Feasibility, Acceptability, and Impact on 30-40 Adolescents.
Many young people who have experienced traumatic events such as sexual assault, domestic violence, serious accidents, or natural disasters face long waits before they can begin full trauma-focused therapy.
- Conditions
- Wellbeing, Mental Health, Psychological, Stress
- Trial name
- CISS (NCT07558005)
- Testing
- Cue-Centered Therapy (CCT)-Informed Single Session Intervention (CISS)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Prader-Willi Syndrome
Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess the utility of Guanfacine Extended Release (GXR) in the management of patients with Prader Willi Syndrome (PWS) who have significant aggression or self-injury.
- Trial name
- NCT04066088
- Testing
- Guanfacine extended release (GXR)
- Where
- United States
- Sponsor
- NYU Langone Health