Clinical trials: Multiple Trauma/Injuries
Drug-induced Liver Injury
A Prospective Cohort Study on Drug-induced Liver Injury in China（DILI-P）
This is a multi-center, prospective, non-interventional cohort study . Its primary objectives are: 1. assess DILI patients' clinical characteristics, disease progression and influencing factors in clinical practice; 2.
- Trial name
- DILI-P (NCT02961413)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Drug Induced Liver Disease Study Group
Traumatic Injuries, Prehospital Emergency Care
Study of Pre Hospital Management of Polytrauma Patients by Medical Teams From a Department in the Parisian Region
To study the impact of prehospital management duration by SMUR teams in the Essonne department (91) on early patient mortality (within 24 hours) and to analyze the procedures performed on scene.
- Conditions
- Traumatic Injuries, Prehospital Emergency Care, Early Mortality
- Trial name
- DELTA-91 (NCT07414186)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Sud Francilien
Trauma, Multiple Trauma
Establishment of Regional Severe Trauma Management System
To evaluate the effects of trauma treatment team establishment on the treatment of patients with severe trauma.
- Conditions
- Trauma, Multiple Trauma, Emergencies
- Trial name
- NCT03363880
- Testing
- trauma treatment team, Basic experimental settings
- Volunteers
- 7,250 people
- Sponsor
- Peking University People's Hospital
Post Traumatic Induced Spasticity
Selective Dorsal Rhizotomy as a Cost Effective and Safe Procedure as a Alternative to Intrathecal Baclofen Pump in Patients With Post Traumatic Spasticity
The investigators will investigate the selective dorsal rhizotomy in post traumatic brain and spinal cord injury induced spasticity to evaluate the efficacy of this procedure in reducing the tone of the spastic muscle groups.
- Trial name
- NCT07583277
- Testing
- Selective dorsal rhizotomy with neuromonitoring
- Volunteers
- 32 people
- Sponsor
- Assiut University
Femur Fracture
Study Comparing Ultrasound-guided FICNB Block to Systemic Analgesia in Treatment of Pediatric Femur Fracture
The goal of this prospective observational study is to compare pain control strategies in children with femur fractures. Researchers will compare ultrasound-guided fascia iliaca compartment nerve block to IV pain control alone.
- Trial name
- PLEXUS (NCT05947292)
- Testing
- Ultrasound-Guided Fascia Iliaca Compartment Nerve Block
- Where
- 10 sites in United States, Australia
- Volunteers
- 114 people
- Sponsor
- Zachary Binder
Tranexamic Acid Effect in Pediatric Polytraumatized Patients
Tranexamic Acid Effect in Pediatric
The study will compare mortality and blood transfusion amounts among severely polytraumatized pediatrics who did or did not receive tranexamic acid within 3 h of injury, based on Injury Severity Score (ISS) and indicators of…
- Trial name
- NCT06097611
- Testing
- Tranexamic Acid administration
- Volunteers
- 74 people
- Sponsor
- Assiut University
Multiple Injuries of Hand (Disorder)
The Efficacy of Hand Injuries Rehabilitation Intervention Program That Incorporated Ethnic and Cultural Reference
The study has three main phases. The first phase included A. Adjustment of research tools. Phase B. will examine the efficacy of the cultural intervention. Phase C.
- Trial name
- NCT05891704
- Testing
- Hand therapy Rehabilitation intervention program that incorporate cultural reference, Conventional Hand therapy Rehabilitation intervention program
- Where
- Palestinian Territories
- Volunteers
- 100 people
- Sponsor
- Tel Aviv University
Pancreatitis, Acute
Resolution of Organ Injury in Acute Pancreatitis - RESORP
Acute pancreatitis (AP) is inflammation of the pancreas usually triggered by gallstones or drinking excessive alcohol. 80% of people who have an episode of AP will recover without complications.
- Trial name
- RESORP (NCT03342716)
- Where
- United Kingdom
- Volunteers
- 229 people
- Sponsor
- University of Edinburgh
Developmental Dislocation of the Hip, Congenital Dislocation of Hip
A Trial on the Opportunity and Treatment of Residual Deformity After Reduction in Developmental Dislocation of the Hip
Developmental dislocation of the hip is a common disease in children, and its incidence in China is about 9 ‰.The pathological changes of it is complex.
- Conditions
- Developmental Dislocation of the Hip, Congenital Dislocation of Hip, Residual Deformity, Reduction
- Trial name
- NCT02163603
- Testing
- Pelvic osteotomy
- Volunteers
- 2 people
- Sponsor
- Hongwen Xu
ACL Tear, Post Operative Pain
Impact of Opioid Avoidance Protocol for ACL Reconstruction
This is a prospective, quasi-experimental, cohort study comparing patients treated with one of two postoperative pain management protocols.
- Trial name
- NCT06340932
- Testing
- Iovera, Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Matthew Varacallo
Heat Stroke
Mechanism Study of G Protein-coupled Receptor 81 in Multiple Organ Dysfunction of Heat Stroke
Heat stroke is one of the common acute and critical conditions in the ICU, characterized by a high incidence and mortality rate, and there is still a lack of effective and precise treatment methods.
- Trial name
- NCT07346443
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Traumatic Injuries, Traumatic Injury of Spine
Human Impact Exposure Onboard High-Speed Boats
Operating high-speed boats is dangerous. The purpose of this study is to establish what levels and what characteristics of impact exposure cause injuries.
- Conditions
- Traumatic Injuries, Traumatic Injury of Spine, Traumatic Head Injury
- Trial name
- MASHIEN (NCT05299736)
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Surgical Site Infection, Surgical Wound Infection
ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions
ROSSINI 2 is a phase III, multi-arm, multi-stage (MAMS) pragmatic, blinded (patient and outcome assessor), multicentre, randomised controlled trial (RCT) with an internal pilot, to evaluate the use of several in-theatre…
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Surgery--Complications, Surgery
- Trial name
- ROSSINI 2 (NCT03838575)
- Testing
- 2% alcoholic chlorhexidine skin prep (SKIN PREP), Iodophor Antimicrobial Incise Drapes (DRAPE), Gentamicin-impregnated implants/ sponges (SPONGE)
- Where
- 2 sites in United Kingdom
- Volunteers
- 6,610 people
- Sponsor
- University of Birmingham
Trauma
Comparative Analysis of MGAP and GAP Trauma Scores in Predicting Outcomes for Multiple Trauma Patients
The goal of this prospective cohort study is to compare the predictive accuracy of the MGAP and GAP trauma scores in determining the prognosis of multiple trauma patients admitted to the emergency department at Al-Kadhimiya…
- Trial name
- MGAP-GAP (NCT06732791)
- Where
- Iraq
- Volunteers
- 522 people
- Sponsor
- Al-Nahrain University
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Emergencies, Trauma Injury
Pre-Hospital Zone 1 Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Injured Patients With Exsanguinating Sub-diaphragmatic Haemorrhage
It is unknown whether this evolved strategy (Pre-Hospital Zone I P-REBOA) is feasible and with an acceptable safety profile. This study will address this question, therefore informing the design of a prospective multicentre…
- Conditions
- Emergencies, Trauma Injury, Trauma, Multiple
- Trial name
- P-PRO (NCT04145271)
- Testing
- Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
- Where
- 4 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- Barts & The London NHS Trust
Fractures, Musculoskeletal
Enhancing Diagnostic Accuracy in Fracture Identification on Musculoskeletal Radiographs Using Deep Learning
This retrospective study aims to evaluate the effectiveness of artificial intelligence (AI) in identifying fractures on musculoskeletal X-rays.
- Trial name
- NCT06644391
- Testing
- Carebot AI Bones
- Where
- Czechia
- Volunteers
- 600 people
- Sponsor
- Carebot s.r.o.
Compartment Syndromes, Polytrauma
Non-invasive Limb Compartment Pressure Measurement
Compartment syndrome (CS) is a serious complication of soft-tissue injuries in patients with fractures of the musculoskeletal apparatus.
- Conditions
- Compartment Syndromes, Polytrauma, Burn Injury
- Trial name
- FNO-TRAUMA-CPM (NCT03730688)
- Testing
- Conventional compartment pressure measurement, Experimental compartment pressure measurement
- Where
- 2 sites in Czechia
- Volunteers
- 70 people
- Sponsor
- University Hospital Ostrava
Disaster, PTSD
Feasibility and Efficacy of a Digital Mental Health Intervention for Teen Wildfire Survivors
In October, 2017, Northern California experienced devastating and historic wildfires. Sonoma Rises is an app designed for anyone who was impacted by this event and is intended to help survivors of disaster find their new normal.
- Conditions
- Disaster, PTSD, Adolescent Behavior, Trauma
- Trial name
- NCT03868761
- Testing
- Sonoma Rises
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Stanford University
Blunt Injury of Thorax, Flail Chest
Treatment of Acute, Unstable Chest Wall Injuries
Unstable chest injuries are common in poly trauma patients. They can lead to severe pulmonary restriction, loss of lung volume, difficulty with ventilation and can render the patient to require intubation and mechanical…
- Conditions
- Blunt Injury of Thorax, Flail Chest, Chest Wall Injury Trauma, Rib Fracture
- Trial name
- NCT01367951
- Testing
- Surgical fixation
- Where
- Canada
- Volunteers
- 207 people
- Sponsor
- Unity Health Toronto