Clinical trials: Murmur, Heart
Heart Valve Diseases
Cardiovascular Acoustics and an Intelligent Stethoscope
The aim of the project is to develop an artificial intelligence software capable of analysing heart sounds to provide early diagnosis of a variety heart diseases at an early stage.
- Trial name
- CAIS (NCT04445012)
- Where
- 5 sites in United Kingdom
- Volunteers
- 1,150 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Heart Murmurs, Mitral Valve Prolapse
Automatic Differentiation of Innocent and Pathologic Murmurs in Pediatrics
The purpose of this preliminary clinical study is to assess the quality of a computational algorithm that automatically classifies murmurs of phonocardiograms (PCGs) as either pathologic (AHA class I) or as no- or innocent (AHA…
- Conditions
- Heart Murmurs, Mitral Valve Prolapse, Systolic Murmurs
- Trial name
- NCT02512341
- Testing
- Computer Aided Auscultation (CAA)
- Where
- Canada
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- CSD Labs GmbH
Murmur, Heart, Rhythm; Abnormal
Evaluation of Cardiags Trimod for Analysis of Cardiac Activity
The current study concerns Cardiags Trimod, a new non-invasive medical device for cardiac examinations. The evaluation of its effectiveness is done relative to specific standard devices.
- Trial name
- EVALTRIMOD (NCT05162599)
- Testing
- Diagnostic study, experimental evaluative cross-sectional study
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- CARDIAGS
Congenital Heart Disease (CHD)
Can Smartphones Listen to Your Heart? A Performance Study on Detecting Inborn Heart Diseases in Your Heart Sounds
This observational study aims to assess the performance of the software called ausculto™. ausculto™ is a collection of computer algorithms that intend to analyse heart sounds recorded from the built-in microphone of a smartphone…
- Trial name
- AUSC-CHD (NCT07376785)
- Testing
- Computer algorithms
- Where
- 2 sites in Hong Kong
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Heart Murmurs, Mitral Valve Prolapse
Automated Algorithm Based Analysis of Phonocardiograms of Newborns
The purpose of this double-blind pivotal clinical utility study is to determine on a large patient population whether heart murmurs can be reliably detected with high sensitivity and specificity using a locked, automated…
- Conditions
- Heart Murmurs, Mitral Valve Prolapse, Systolic Murmurs
- Trial name
- NCT02105480
- Testing
- Computer aided auscultation (CAA)
- Where
- Austria
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- CSD Labs GmbH
Heart Murmur
Study of Two Teaching Techniques to Teach Cardiac Auscultation to Physicians
Our objective was to test two educational interventions for teaching cardiac auscultation: self-directed learning using portable audio files versus a single, massed multimedia lecture intervention similar to current best…
- Trial name
- NCT01596465
- Testing
- Self-Study using MP3 Player, Multimedia Lecture
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- The Reading Hospital and Medical Center
Heart Failure, Diastolic (HFpEF)
Pogejiuxin Decoction Combination of Conventional Western Medicine for the Treatment of Heart Failure With Preserved Ejection Fraction
The objective of this study is to investigate the potential of Pogejiuxin Decoction to enhance the efficacy and mitigate the adverse effects associated with conventional treatment in patients with heart failure and preserved…
- Trial name
- NCT06629246
- Testing
- Conventional heart failure treatment, Pogejiuxin decoction combined with conventional heart failure treatment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chongqing Traditional Chinese Medicine Hospital
Congenital Heart Disease
Cardiac Murmurs in Children: Predictive Value of Cardiac Markers
Heart murmurs are commonly discovered in young children during clinical encounters in general practice. Heart murmurs might signal a structural cardiac disease that need to be treated, such as atrial septal defect.
- Trial name
- CAMUS (NCT02746029)
- Testing
- Clinical examination
- Where
- Norway
- Volunteers
- 500 people
- Sponsor
- University Hospital, Akershus
Heart Failure, Heart Murmurs
Retrospective Evaluation of Carvedilol Versus Captopril in CHF Patients
This is a retrospective chart review examining our experience with carvedilol in CHF secondary to left-to-right heart shunt lesions. The treatment group will be children who have received carvedilol.
- Trial name
- NCT00249067
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Healthcare of Atlanta
Chest Pain
Understanding Pediatric Chest Pain and Other Symptoms
The causes of pediatric pain are often not the same for every child. Most children who visit a cardiology specialist with complaints of chest or other somatic pain have no known medical diagnosis to explain their symptoms.
- Trial name
- NCT00166231
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Emory University
Heart Murmurs, Pathologic Murmurs
eMurmur ID - Clinical Performance Evaluation
The differentiation between innocent and pathologic murmurs through traditional auscultation can often be challenging, which in the end makes the diagnosis strongly dependent on the clinitians experience and clinical expertise.
- Conditions
- Heart Murmurs, Pathologic Murmurs, Innocent Murmurs, Congenital Heart Defect
- Trial name
- NCT03227848
- Testing
- Automated Heart Murmur Detection AI
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- CSD Labs GmbH
Heart Murmurs, Wheezing
Validate the Efficacy and the Safety of the Keikku Electronic Stethoscope for Its Indication and Intended Purpose, Under the Intended Conditions of Use.
This study is testing a digital stethoscope called the Keikku electronic stethoscope. Doctors use stethoscopes to listen to the heart, and this new device records heart sounds using a smartphone app.
- Trial name
- KCI-1 (NCT07044128)
- Testing
- Digital stethoscope using MEMS sensor and mobile application for cardiac auscultation
- Where
- Peru
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Lapsi Health Holding B.V.
Heart Murmurs, Congenital Heart Disease
The Accuracy of an Artificially-intelligent Stethoscope
This study will characterize the accuracy of a commercially available artificially-intelligent stethoscope in determining which childhood murmurs suggest underlying congenital structural heart disease and therefore warrant…
- Conditions
- Heart Murmurs, Congenital Heart Disease, Structural Heart Disease
- Trial name
- NCT00564122
- Testing
- Artificially-Intelligent Stethoscope, Physical Examination
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Akron Children's Hospital
Heart Murmurs
: A Prospective Study Investigating the Use of the Eko CORE and Eko DUO Electronic Stethoscopes in Pediatric Patients.
The Eko CORE and DUO stethoscopes are FDA approved electronic devices which have the capacity to record heart sounds. This study will utilize these devices to see if they can differentiate between pathologic and innocent heart…
- Trial name
- NCT04317521
- Testing
- Use of EKO Core and EKO Duo electronic stethoscopes
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Heart Murmurs, Fever
Modifications of Heart Murmurs and Cardiac Output During Fever
The combination of fever and auscultation of a heart murmur suggests the diagnosis of endocarditis. However, fever itself increases cardiac output and could therefore modify heart sounds.
- Trial name
- FeMur (NCT04306991)
- Testing
- Auscultation using an electronic stethoscope (EKO CORE 4)
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers