Clinical trials: Muscle
Hyperkyphosis, Adolescent, Muscle Activation
Schroth and Scapular Muscle Activation in Hyperkyphosis
This randomized controlled trial aims to investigate the effects of Schroth exercises on scapular muscle activation in children with thoracic hyperkyphosis.
- Conditions
- Hyperkyphosis, Adolescent, Muscle Activation, Scapula; Deformity, Acquired, Exercise Therapy
- Trial name
- NCT06907914
- Testing
- Schroth
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Urinary Incontinence
Trial Study of the Efficacy of Intensive Preoperative Pelvic Floor Muscle Training to Decrease Post-prostatectomy Urinary Incontinence
Urinary incontinence after radical prostatectomy is a significant clinical problem despite advances in surgical techniques. In the literature, the incidence of post prostatectomy urinary incontinence varies widely from 0.5 to 87%…
- Trial name
- NCT01338584
- Testing
- Pelvic floor muscle training 3 weeks before radical prostatectomy, Intensive preoperative pelvic floor muscle training
- Where
- Hong Kong
- Volunteers
- 84 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Panniculitis, Dermatomyositis
Panniculitis in Dermatomyositis
Adipose tissue involvement is rare in dermatomyositis. The occurrence of partial or diffuse lipodystrophy is a rare but well-characterized manifestation, particularly in juvenile forms of dermatomyositis.
- Trial name
- PANNICUL (NCT07345949)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Cystic Fibrosis, Covid19
The Effects of Telerehabilitation on Muscle Function, Physical Activity and Sleep in Cystic Fibrosis During Pandemic
The aim of this study is to evaluate the peripheral muscle function, sleep disorders and physical activity level in children with cystic fibrosis who are physically inactive at home due to social isolation and to examine the…
- Conditions
- Cystic Fibrosis, Covid19, Social Isolation
- Trial name
- NCT04742049
- Testing
- Telerehabilitation-based, Follow-up based
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Spasticity, Muscle
Efficiency of the Super Inductive System in Spasticity Treatment
The aim of the study is to see whether a physical therapy program can relieve pain, decrease spasticity and increase muscle contraction force by using the super inductive system (high frequency electromagnetic field).
- Trial name
- NCT04190238
- Testing
- Super inductive system (high frequency electromagnetic field), Physical therapy
- Where
- Romania
- Volunteers
- 60 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Strabismus, Comitant
Single Minimal Conjunctival Incision for Strabismus
The purpose of this investigation is to study the feasibility and inflammatory response of surgery for rectus muscles using a small single bulbar conjunctival incision posterior and parallel to the muscle insertion.
- Trial name
- NCT05987878
- Testing
- single minimal conjunctival incision
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidad Autonoma de Madrid
Muscular Dystrophies, Muscle Myopathies
Genetic and Physical Study of Childhood Nerve and Muscle Disorders
Background: Some nerve and muscle disorders that start early in life (before age 25), like some forms of muscular dystrophy, can run in families. However, the genetic causes of these disorders are not known.
- Conditions
- Muscular Dystrophies, Muscle Myopathies, Hereditary Spastic Paraplegias, Inherited Neuropathies
- Trial name
- NCT01568658
- Where
- United States
- Volunteers
- 2,586 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Muscular Dystrophies
Diaphragm Ultrasound in Neuromuscular Disorders
Muscular dystrophies are neurologic disease with higher morbidity and mortality. Cardiac function and respiratory muscles can be affected, in addition with skeletal muscle deficiency .
- Trial name
- NCT04045158
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Fibromyalgia, Fibromyalgia Syndrome
PRL2019 in the Treatment of Juvenile Fibromyalgia
Juvenile Fibromyalgia Syndrome (JFS) is a chronic condition affecting children and adolescents, characterised by widespread musculoskeletal pain and a significant impact on daily life and quality of life.
- Trial name
- IGG-microbiota (NCT07738926)
- Testing
- Bifidobacterium adolescentis PRL2019
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Giannina Gaslini
Inherited Mitochondrial Disease
A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease
The primary objective of this study is to assess the safety of vatiquinone in participants with inherited mitochondrial disease who had prior exposure to vatiquinone in a PTC/BioElectron sponsored (previously Edison) clinical…
- Trial name
- NCT05218655
- Testing
- Vatiquinone
- Where
- 26 sites in United States, France and 5 more
- Volunteers
- 101 people
- Sponsor
- PTC Therapeutics
Lower Urinary Tract Disorder
Pelvic Floor Muscle Activity, Respiratory Functions, Respiratory Muscle Strength, and Functional Capacity in Children With Lower Urinary Tract Dysfunction
The functional disorders of the lower urinary tract in children involve overactive bladder with thickening of the bladder muscle, resulting in a decrease in functional bladder volume and an increase in intra-bladder pressure.
- Trial name
- NCT06652178
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Activities of Daily Living, Postural Control
Effect of Callisthenic Training on Mobility and ADL Performance in Spastic Diplegic Cerebral Palsy Patients
Almost 2 to 3 out of every 1000 children have Cerebral palsy in Pakistan.Spastic type of CP is dominant about 75%, diplegia (40%) and hemiplegic are (35.5%).Spastic diplegics have tightness of lower limb more than upper…
- Conditions
- Activities of Daily Living, Postural Control, Spasticity, Mobility
- Trial name
- NCT06966076
- Testing
- calisthenic training, Conventional physical therapy group
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Fibrodysplasia Ossificans Progressiva
A Study to Assess the Effectiveness and Safety of 2 Dosage Regimens of Oral Fidrisertib (IPN60130) for the Treatment of Fibrodysplasia Ossificans Progressiva (FOP).
Fibrodysplasia Ossificans Progressiva (FOP) is a rare, severely disabling disease characterized by the presence of bone in soft tissue where bone normally does not exist, known as Heterotopic Ossification (HO).
- Trial name
- FALKON (NCT05039515)
- Testing
- IPN60130
- Where
- 25 sites in United States, Argentina and 12 more
- Volunteers
- 113 people
- Sponsor
- Clementia Pharmaceuticals Inc.
Fatigue Syndrome, Chronic, Bone Tumor
The Assessment of Fatigue and Quality of Life in Patients With Bone Tumor,
The aim of the present observational study is to evaluate and describe the evolution over time of the fatigue and the quality of life of patients with bone tumor, in Rizzoli Orthopedic Institute, Chemotherapy ward, during the…
- Conditions
- Fatigue Syndrome, Chronic, Bone Tumor, Quality of Life
- Trial name
- Fatigue-ONCO (NCT04104750)
- Testing
- assessment scales (BFI, QLQ, TESS)
- Where
- Italy
- Volunteers
- 155 people
- Sponsor
- Istituto Ortopedico Rizzoli
Muscular Atrophy, Spinal
A Study to Learn About the Safety and Effects of Salanersen (BIIB115) When Given to Babies With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene Abeparvovec
In this study, researchers will learn more about the safety and effects of BIIB115, also known as salanersen. Specifically, researchers will learn more about how salanersen works in babies who have already been treated with…
- Trial name
- STELLAR-2 (NCT07444450)
- Testing
- Salanersen
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Biogen
Duchenne Muscular Dystrophy, Natural History
phenotypeS in Non Ambulant Duchenne Muscular Dystrophy
The aims of the study are to prospectively collect information on several aspects of function in non-ambulant DMD patients by using a structured battery of tests including motor, respiratory and cardiac function
- Conditions
- Duchenne Muscular Dystrophy, Natural History, Motor Function; Retardation
- Trial name
- GUP21003 (NCT06366815)
- Testing
- Different Phenotypes of non ambulant patients with Duchenne Muscular Dystrophy
- Where
- 2 sites in Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Dislocation, Total Hip Arthroplasty
Preoperative Gluteal Muscle Atrophy: A Silent Predictor of THA Dislocation.
This study looks at how fat buildup in hip muscles relates to hip osteoarthritis and less favorable recovery after hip replacement surgery.
- Conditions
- Dislocation, Total Hip Arthroplasty, Muscle Degeneration
- Trial name
- NCT06571604
- Testing
- Dislocation, No dislocation
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Mechanical Ventilation
Study of Muscle Effects of BYM338 in Mechanically Ventilated Patients
The purpose of this study is to evaluate the effect of BYM338 on muscle mass and function in Group III failure to wean patients, as compared to placebo controls.
- Trial name
- NCT01868685
- Testing
- BYM338
- Sponsor
- Novartis Pharmaceuticals
Duchenne Muscular Dystrophy
Efficacy of Umbilical Cord Mesenchymal Stem Cells in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a genetic disorder caused by an absence of dystrophin and characterized by progressive muscle degeneration.
- Trial name
- NCT02285673
- Testing
- Umbilical Cord Mesenchymal Stem Cell
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Acibadem University
Duchenne Muscular Dystrophy (DMD)
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping
The primary purpose of this study is to evaluate the safety, tolerability, and dystrophin protein levels in muscle tissue following multiple intravenous (IV) doses of DYNE-251 in participants with Duchenne muscular dystrophy…
- Trial name
- DELIVER (NCT05524883)
- Testing
- DYNE-251
- Where
- 30 sites in United States, Australia and 7 more
- Volunteers
- 86 people
- Sponsor
- Dyne Therapeutics
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