Clinical trials: Muscle Disorders
Bone Sarcoma, Soft Tissue Sarcoma
Preoperative Immunonutrition in Patients With Bone and Soft Tissue Sarcomas
This study will evaluate whether a short nutritional intervention before surgery can improve recovery in patients with bone and soft tissue sarcomas.
- Conditions
- Bone Sarcoma, Soft Tissue Sarcoma, Sarcopenia, Malnutrition
- Trial name
- NCT07609329
- Testing
- Forticare Advanced oral nutritional supplement
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
ALS, Autism Spectrum Disorder
Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products
This is an observational study of medical marijuana manufactured and dispensed by Ilera and given as standard treatment for a variety of approved serious medical conditions as defined by individual state law.
- Conditions
- ALS, Autism Spectrum Disorder, Cancer, Spasticity, Muscle
- Trial name
- Ilera (NCT03886753)
- Testing
- Registry, PK microsampling of blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Cardiomyopathy
New Horizons for the Treatment of Cardiomyopathy in Children
Collecting mono nuclear cells from the patient's blood after a course of granulocyte stimulation then injecting them into the weak heart muscle measuring the heart function at the beginning and after 2.4.6 months to assess the…
- Trial name
- NCT04893629
- Testing
- mono nuclear cells injection, Digoxin+furosemide+captopril
- Where
- Syria
- Volunteers
- 22 people
- Sponsor
- Damascus University
Lower Back Pain, Pelvic Pain
Musculoskeletal and Obstetric Management Study
The investigators propose such a trial to compare a Musculoskeletal and Obstetric Management (MOM) program to standard obstetric care alone for lower back pain/pelvic pain (LBP/PP) during and after pregnancy.
- Conditions
- Lower Back Pain, Pelvic Pain, Musculoskeletal Pain
- Trial name
- MOMS (NCT00905112)
- Testing
- Manual Therapy, Standard OB Care
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- Logan College of Chiropractic
Cerebral Palsy (CP)
Local Vibration for Drooling in Children With Cerebral Palsy
This randomized-controlled trial evaluates local vibration therapy for drooling and orofacial muscle biomechanics in children with cerebral palsy.
- Trial name
- NCT07626424
- Testing
- Local Vibration Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Bitlis Eren University
Duchenne Muscular Dystrophy
Treatment Effect of Tamoxifen on Patients With DMD
Duchenne muscular dystrophy (DMD) is a progressive devastating disease that affects mainly boys, with an incidence of about 1:3,500 live births.
- Trial name
- NCT02835079
- Testing
- Tamoxifen
- Volunteers
- 19 people
- Sponsor
- Hadassah Medical Organization
Spastic Cerebral Palsy (sCP)
Biomechanical and Functional Effects of Adding Sensory-Threshold Electrical Stimulation to Neurodevelopmental Therapy in Children With Spastic Cerebral Palsy: A Single-Arm Repeated-Measures Study
This study investigates whether adding sensory-level electrical stimulation to an ongoing neurodevelopmental treatment program is associated with changes in ankle mobility, spasticity-related measures, muscle mechanical…
- Trial name
- NCT07491341
- Testing
- Sensory Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people
- Sponsor
- Harran University
TMJ Disorder
MJ Arthrocentesis Using the Dental Implant Motor Irrigation Pump and the Conventional Technique in Treatment of Internal Derangement
Background: Millions of individuals worldwide suffer from temporomandibular joint (TMJ) disorders and are characterized by pain and joint dysfunction.
- Trial name
- NCT07239037
- Testing
- Motor irrigation with 80% power, Motor irrigation with 40% power, conventional TMJ arthrocentesis
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Cerebral Palsy, Muscle Spasticity
Botulinum Toxin (BOTOX) for Cerebral Palsy
This study examines botulinum toxin (BOTOX, or BTX) for the treatment of muscle twitches and spasticity associated with cerebral palsy in children.
- Trial name
- NCT00060957
- Testing
- Botulinum toxin type A
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Muscular Dystrophy, Muscular Disease
Studying Skeletal Muscle, Heart, and Diaphragm Imaging in Boys With Duchenne Muscular Dystrophy
Background: Duchenne muscular dystrophy (DMD) is a disease in which the muscles are unable to make the protein dystrophin. Without this protein, the muscles become gradually weaker.
- Trial name
- NCT01451281
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Non-muscle-invasive Bladder Cancer
Safety and Efficacy of Scheduled Intravesical Gemcitabine Versus Intravesical BCG for Intermediate and High Risk Non Muscle Invasive Bladder Cancer: A Prospective, Randomized Study
About 40%-80% of NMIBC recur within 6-12 months when managed with TURBT alone, and 10%-25% of the patient's progress to muscle invasive disease.
- Trial name
- NCT05626101
- Testing
- BCG, Gemcitabine
- Where
- Egypt
- Volunteers
- 280 people
- Sponsor
- Al-Azhar University
Mitochondrial Diseases, Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation
The KHENERGYC Study
This a randomized placebo controlled, double-blind phase II study to explore the pharmacokinetics, safety and efficacy of sonlicromanol in children (from birth to 17 years) with genetically confirmed mitochondrial disease of…
- Conditions
- Mitochondrial Diseases, Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation, MELAS, Subacute Necrotizing Encephalomyelopathy
- Trial name
- NCT04846036
- Testing
- Sonlicromanol
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Khondrion BV
Asthma (Diagnosis)
Effects of Respiratory Muscle Strength Training in Children With Asthma
Asthma is a common long-term respiratory condition in children. In addition to affecting breathing, asthma may affect physical activity, exercise capacity, daily functioning, and quality of life.
- Trial name
- NCT07880145
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Hasan Kalyoncu University
Duchenne Muscular Dystrophy (DMD)
Virtual Reality and Whole Body Vibration on Muscle Strength and Balance in Children With DMD
we measure balance and quadriceps strength in Duchenne muscular dystrophy children after applying virtual reality and whole body vibration
- Trial name
- NCT07338812
- Testing
- virtual reality, whole body vibration
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Cerebral Palsy, Muscle Contracture
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies.
Cerebral palsy (CP) is a motor impairment due to a brain malformation or a brain lesion before the age of two. Spasticity, hypertonus in flexor muscles, dyscoordination and an impaired sensorimotor control are cardinal symptoms.
- Conditions
- Cerebral Palsy, Muscle Contracture, Spasticity, Muscle
- Trial name
- CPMuscleSL (NCT05518565)
- Testing
- No intervention
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Eva Ponten
Chronic Fatigue Syndrome
ME/CFS, Hypermobility and Craniocervical Obstructions
A retrospective study on clinical and radiological findings in ME/CFS
- Trial name
- NCT04399330
- Where
- Sweden
- Volunteers
- 225 people
- Sponsor
- Bragee Clinics
Cystic Fibrosis
Inspiratory Muscle Training in Individuals With Cystic Fibrosis
Cystic fibrosis is a genetic disease that affects some organs of the human body. Among them, the lungs tend to be the most affected due to the accumulation of mucus in the airways, which in addition to avoiding the passage of…
- Trial name
- NCT03737630
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Scoliosis Idiopathic, Scoliosis; Adolescence
Back Muscle Function in Adolescents With Idiopathic Scoliosis
The function and asymmetry of back muscles will be examined in different positions and with specific spinal corrections based on scoliosis pattern and according to the "Schroth method" in adolescents with idiopathic scoliosis.
- Trial name
- NCT05961228
- Testing
- exercise
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Myotonic Dystrophy Type 1
Children's Health Research Institute(CHRI), Stanford Lucile Packard Children Hospital (LPCH) Protocol on Myotonic Dystrophy
Study to focus on the defining and managing the neuropsychological abnormalities of myotonic dystrophy and to find out if the neuropsychological abnormalities have any correlation with changes seen on Magnetic Resonance Imaging.
- Trial name
- CHRI (NCT02269865)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Duchenne Muscular Dystrophy
Electrical Impedance Myography and Ultrasound as Biomarkers of Duchenne Muscular Dystrophy
Researchers at Children's Hospital Boston Neurology Department invite children to participate in a new research study. Researchers are looking for boys ages 2 - 30 with Duchenne Muscular Dystrophy (DMD) and healthy boys ages 2 …
- Trial name
- QED (NCT01491555)
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
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