Clinical trials: Muscle Relaxation
Strabismus
Deep Neuromuscular Blockade in Strabismus Surgery
The purpose of this study is to determine if inducing a moderate or greater neuromuscular block (TOF count 0-3) when performing a neuromuscular block in pediatric patients aged 3 to 18 years undergoing strabismus surgery under…
- Trial name
- NCT05882643
- Testing
- moderate to deep neuromuscular blockade, shallow to minimal neuromuscular blockade
- Where
- South Korea
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Acupuncture, Tumor, Brain
Evaluation of Acupuncture Effects for Complications After Surgery of Cerebellopontine Angle Tumor in Skull Base
Skull base tumors are a type of tumor that grow in the area of several skulls behind the cranial cavity. The incidence rate is 2 to 18 per 100,000 people per year; males and females are likely to have a proportional difference in…
- Conditions
- Acupuncture, Tumor, Brain, Skull Base Tumor, Cerebellopontine Angle Tumor
- Trial name
- NCT04249921
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Paraspinal Muscle Relaxation in Spine Surgery
Paraspinal Muscle Relaxation in Spine Surgery
During anesthesia, neuromuscular blocking agents (NMBA) are routinely used for relaxation of muscles necessary for the conduction of the surgical procedure.
- Trial name
- TOF (NCT03318718)
- Testing
- Anesthesia with non-depolarizing NMBA Rocuronium, TOF measurement, MEP measurement
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Balgrist University Hospital
Endotracheal Intubation, Hemodynamics
Endotracheal Intubation Using Bonfils Fibrescope Without Neuromuscular Blockade
We studied intubating conditions and hemodynamic changes during endotracheal intubation employing either Bonfils intubating fiberscope or the conventional Macintosh laryngoscopy in 80 healthy patients candidates for elective…
- Conditions
- Endotracheal Intubation, Hemodynamics, Neuromuscular Blockade
- Trial name
- NCT00620386
- Testing
- Bonfils, Macintosh
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Tehran University of Medical Sciences
Neuromuscular Block, Residual
Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in Children
This study is to evaluate the recovery of diaphragm function and atelectasis after reversal of neuromuscular blockade with Neostigmine and Sugammadex using lung ultrasound and diaphragm ultrasound for children aged 2 to 7 who are…
- Trial name
- NCT05724550
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Postural Balance, Gait
Efficacy of Non-Nutritive Sucking (NNS) on Balance and Gait Measured in 12-42 Month-Old Healthy Children Over 36 Months
No one disputes that fetal sucking in the womb is a natural human right. Available information on whether, how and when to stop children's sucking habits comes from popular cultural misunderstandings and lack of sound…
- Conditions
- Postural Balance, Gait, Non-nutritive Sucking, Sleep
- Trial name
- NNSbenefits (NCT03801785)
- Testing
- Pacifier
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Migraine, Tension Type Headache
The Efficacy of a Cognitive and Physical Intervention to Reduce Head and Muscle Pain in a Working Community
This study is a controlled, cluster randomised, interventional trial to evaluate the effectiveness of a workplace cognitive and physical program (Intervention), in reducing the frequency of head and neck pain in an extensive…
- Conditions
- Migraine, Tension Type Headache, Cervical Pain
- Trial name
- NCT00551980
- Testing
- Cognitive, Relaxation, Exercise Therapy
- Where
- Italy
- Volunteers
- 2,895 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Neuromuscular Blockade, Delayed Emergence From Anesthesia
Sugammadex Timing and Recovery Profile in Pediatric Adenotonsillectomy
Sugammadex is routinely used to reverse rocuronium-induced neuromuscular blockade in children. In clinical practice, it is given either while the child is still deeply anesthetized or after the anesthetic has lightened.
- Conditions
- Neuromuscular Blockade, Delayed Emergence From Anesthesia, Emergence Agitation
- Trial name
- SUGA-PED (NCT07902193)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Namik Kemal University
Muscle Relaxation, Anesthesia
Continuous Infusion Versus Intermittent Bolus Injection of Rocuronium
The research is to find out whether continuous infusion of rocuronium requires more or less amount of rocuronium, per kilogram and per hour, than bolus administered rocuronium during noncardiac surgery.
- Trial name
- RCVB (NCT03060707)
- Testing
- Rocuronium Bromide
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital
Anesthesia
Dexmetomidine in Children Undergoing General Anaesthesia
The effects of dexmedetomidine on the onset of both the general anaesthesia induction and the neuromuscular blockade in children of school age will be investigated.
- Trial name
- NCT03923075
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
Restless Legs Syndrome
Effect of Progressive Muscle Relaxation Exercises in Menopausal Women Experiencing RLS.
Restless legs syndrome is a symptom that can be seen in all stages of a woman's life, but its frequency and severity increases with menopause.
- Trial name
- NCT06156007
- Testing
- progressive muscle relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Gazi University
Sports Physical Therapy
Effects of Post Isometric Relaxation and Post Facilitation Stretching on Young Fast Bowlers
The quadratus lumborum muscle exhibited the highest degree of asymmetry in fast bowlers with low back pain, the identification and correction of this asymmetry is always of interest.
- Trial name
- (PIR)(PFS) (NCT06479538)
- Testing
- Post isometric relaxation, Post facilitation stretching
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Underdosing of Unspecified General Anesthetics
Remifentanil Minimum Effective Dose for Children Intubation Without Neuromuscular Blockade
Introduction: remifentanil's optimal dose for children intubation without neuromuscular blockade is unknown. Method: phase IV adaptative trial using Dixon's up-and-down method for modeling remifentanil's dose-response curve for…
- Trial name
- NCT02454868
- Testing
- Remifentanil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brasilia University Hospital
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Neuromuscular Blockade
Deep Neuromuscular Blockade on Postoperative Pain
This study aims to investigate the impact of varying degrees of neuromuscular blockade on postoperative pain in pediatric patients aged over 2 months to under 7 years undergoing laparoscopic surgery under general anesthesia.
- Trial name
- NCT06679569
- Testing
- rocuronium 0.2 mg/kg/hr continuous infusion, rocuronium 0.6 mg/kg/hr continuous infusion
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Seoul National University Hospital
Neuromuscular Blockade
Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals
Aim: To explore the frequency of use of objective neuromuscular monitoring for assessment of depth of neuromuscular blockade in general anaesthesia the incidence of residual neuromuscular blockade, and the timing of reversal of…
- Trial name
- NCT02914119
- Testing
- Rocuronium, Succinylcholine, Cisatracurium
- Where
- Denmark
- Volunteers
- 30,430 people
- Sponsor
- Jakob Louis Thomsen
Premenstrual Syndrome
Progressive Muscle Relaxation and Kinesio Taping for Premenstrual Syndrome
This randomized controlled trial evaluated the effects of progressive muscle relaxation exercise, kinesio taping, and their combined application on premenstrual symptoms, perceived stress, severity of depressive symptoms, and…
- Trial name
- NCT07791121
- Testing
- Progressive Muscle Relaxation Exercise, Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 194 people
- Sponsor
- ASLI ER KORUCU
Immune Responses, Post Operative Recovery
Comparative Study Between the Effects of Deep Versus Moderate Neuromuscular Blockade on Postoperative Recovery and Immune Function in Patients Undergoing Total Hip Replacement Surgery.
. The investigators hypothesized that DNMB ( Deep NeuroMuscular Block) would yield superior postoperative recovery quality and attenuate the surgery-induced immune suppression compared to MNMB ( Moderate NeuroMuscular Block)in…
- Trial name
- NCT07870954
- Testing
- ToF ( Train of Four) Scan
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Caregiver Burden, Dementia
Progressive Muscle Relaxation Exercise on Care Burden, Depression, Anxiety, and Stress Levels in Dementia Caregivers
Dementia, which leads to deterioration in cognitive and behavioral functions, is a chronic progressive disease. Since the diagnosis is made, the care needs of the patients increase.
- Trial name
- NCT06143826
- Testing
- Progressive muscle relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Atlas University
ARDS
Paediatric Ards Neuromuscular Blockade Study
Paediatric acute respiratory distress syndrome (ARDS) is a manifestation of severe, life-threatening lung injury. Care for paediatric patient is mainly supportive and based on what works in adults and personal experiences…
- Trial name
- PAN (NCT02902055)
- Testing
- Neuromuscular Blocking Agents, Isotonic saline
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- University Medical Center Groningen