Clinical trials: Muscles
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Child, Only
Effect of Pillates on Children With Backpack Syndrome
This randomized clinical trial focuses on a sample of 139 of children diagnosed with backpack syndrome, assessing both subjective pain levels and objective measures of trunk muscle endurance before and after a structured Pilates…
- Trial name
- NCT07248514
- Testing
- Pilates exercise, General Stretching exercises
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Duchenne Muscular Dystrophy
This is a Study to Get More Information About Non Ambulatory Boys & Men With Duchenne Muscular Dystrophy
Many therapeutic trials in DMD exclude non-ambulatory boys and men. Rate of progression in these non-ambulatory patients has been studied but consensus has not been reached for what measures are most reliable and reproducible.
- Trial name
- DMD (NCT01098708)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Upper Gastrointestinal Submucosal Tumors (SMTs), Gastrointestinal Stromal Tumors (GISTs)
ESTD vs. VATS for Upper Gastrointestinal Submucosal Tumors
The purpose of this study is to determine the efficacy and safety of endoscopic submucosal tunnel dissection (ESTD) compared with video-assisted thoracoscopic surgery (VATS) in the treatment of upper gastrointestinal submucosal…
- Conditions
- Upper Gastrointestinal Submucosal Tumors (SMTs), Gastrointestinal Stromal Tumors (GISTs), Leiomyoma
- Trial name
- NCT01768104
- Testing
- ESTD, VATS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Becker Muscular Dystrophy
Safety and Biomarker Response to (+)-Epicatechin in Becker Muscular Dystrophy
This is a Phase 1, open-label, dose escalation study aimed at evaluating the safety, early efficacy and potential biomarkers of (+)-epicatechin in patients with Becker or Becker-like Muscular Dystrophy (BMD).
- Trial name
- NCT04386304
- Testing
- (+)-Epicatechin
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Epirium Bio Inc.
Migraine
Effects Of Dry Needling On Sternocleidomastoid Muscle For Pain And Disability In Migraine
To determine the effects, sequel of dry needling in migraine by resolving MTrPs in sternocleidomastoid muscle. To determine the possession of dry needling technique to mitigate the frequency, intensity and duration of headache.
- Trial name
- NCT05285852
- Testing
- Dry Needling
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Cerebral Palsy (CP)
Comprehensive Hand Repetation Intensive Strength Training on Upper Limb in Children With Cerebral Palsy
Hemiplegia is the medical term for paralysis of one side of the body This means their shoulder; arm, hand, leg and foot are all completely paralyzed..
- Trial name
- CHRIST (NCT06748235)
- Testing
- Intensive Strength Training, Routine Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Duchenne Muscular Dystrophy, Cardiomyopathy
HOPE-Duchenne (Halt cardiomyOPathy progrEssion in Duchenne)
Male participants with cardiomyopathy secondary to Duchenne muscular dystrophy (DMD) meeting all inclusion and no exclusion criteria will be randomized. All participants will be at least 12 years of age.
- Trial name
- HOPE (NCT02485938)
- Testing
- Allogeneic Cardiosphere-Derived Cells (CAP-1002)
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Capricor Inc.
Spinal Muscular Atrophy
Long Term Trajectories of SMA Patients Receiving or Not Disease-modifying Treatments
This is an observational multicenter retrospective and prospective study on natural history of SMA also considering the 'new natural history' secondary to the availability of commercially available therapies.
- Trial name
- NCT05768048
- Where
- 5 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Muscle Disease
Standardization of Quantitative Muscle Ultrasonographic Parameters Among Egyptian Population
1-standardization of semi quantitative muscle ultrasonographic parameters ( muscle thickness (MT) and echo intensity (EI) ) in healthy adults and to obtain a set of normal values of all accessible muscle in both upper and lower…
- Trial name
- NCT05200780
- Testing
- ultrasound
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
ACL Reconstruction, ACL Surgery
Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients
This study is being conducted to learn about how neuromuscular electrical stimulation (NMES) in addition to standard of care aids in the recovery of muscle strength in patients undergoing ACLR procedure.
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy
- Trial name
- NCT07171346
- Testing
- Zynex NexWave Electrotherapy Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas Medical Center
Injury;Sports, Athletic Injuries
Investigation of Injury Risk and Related Factors in Adolescent Male Soccer Players
The aim of this study is to examine the relationship between injury risk and muscle strength, functional performance, and balance in adolescent male soccer players.
- Trial name
- NCT07843680
- Testing
- Physical evaluations in footballers
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Izmir Democracy University
Polyneuropathy, Charcot Marie Tooth Disease (CMT)
Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease)
The goal of this clinical trial is to compare the effects of an 8-week resistance exercise training program on skeletal muscle quality, functional capacity, and quality of life in young individuals aged 15 to 29 years, with and…
- Trial name
- PNP (NCT07152197)
- Testing
- Progressive Resistance Exercise Training
- Where
- 2 sites in Chile
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Duchenne Muscular Dystrophy
Evaluate the Efficacy and Safety of EN001 in Patients With Duchenne Muscular Dystrophy
A Multi-center, Randomized, Double-blind, Placebo-controlled, Phase 1/2 Trial to Evaluate the Efficacy and Safety of EN001 in Patients with Duchenne Muscular Dystrophy
- Trial name
- NCT06328725
- Testing
- EN001
- Where
- 2 sites in South Korea
- Volunteers
- 88 people
- Sponsor
- ENCell
Uterine Fibroid
The Efficacy and Safety of Preoperative Misoprostol in Blood-loss Reduction During Myomectomy.
Open myomectomy remains the principal treatment for symptomatic fibroids in sub-Saharan countries irrespective of fertility desires.
- Trial name
- MM (NCT03509168)
- Testing
- Misoprostol Pfizer Brand, Non-insertion of Misoprostol Pfizer Brand
- Where
- Uganda
- Volunteers
- 46 people
- Sponsor
- Makerere University
Autism
The Relationship Between Sensory Profile and Ankle Muscle Shortness in Children With Autism
The aim of this study was to investigate the relationship between sensory profile and ankle muscle shortness in children with autism.
- Trial name
- NCT07159113
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Abant Izzet Baysal University
Copd, Athletes
Effects of CreaSafe® on Kidney, Muscle, and Cardiopulmonary Function in Athletes and COPD Patients
Creatine supplementation (CS) offers numerous health benefits, with no proven side effects reported to date. CS positively impacts all organs and systems of the body.
- Trial name
- NCT06991426
- Testing
- CreaSafe® creatine
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Pompe Disease
A Pilot Study of Pyridostigmine in Pompe Disease
Pyridostigmine is an acetylcholinesterase inhibitor, which degrades acetylcholine at the neuromuscular junction. Based on recent studies, pyridostigmine may be an effective adjuvant treatment for people with Pompe disease, as it…
- Trial name
- NCT02357225
- Testing
- Pyridostigmine Bromide
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Central Core Disease, Multi-Minicore Disease
The Natural History and Muscle Fatigability of Patients With Congenital Myopathies.
Core myopathies (CCD/MmD), nemaline myopathies (NEM) and centronuclear myopathies (CNM) are three types of rare congenital myopathies.
- Conditions
- Central Core Disease, Multi-Minicore Disease, Nemaline Myopathy, Centronuclear Myopathy
- Trial name
- READYCOM (NCT06157268)
- Testing
- Natural history and non therapeutical therapy
- Where
- 2 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Cerebral Palsy Spastic Diplegia
Effect of Botulinum Toxin on Selective Motor Control and Pain in Diplegic Cerebral Palsy
The aim of this study is to investigate the effects of Botulinum Neurotoxin-A (BoNT-A) injection applied to spastic muscles on pain sensation and Selective Motor Control (SMC) in cases diagnosed with diplegic spastic Cerebral…
- Trial name
- NCT06583343
- Testing
- OnabotulinumtoxinA, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
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