Clinical trials: Muscles
Spastic Hemiplegia
Biomechanical Muscle Properties and Balance in Children With Spastic Hemiplegia
this study will be conducted to investigate the relationship between muscle tone and dynamic stiffness during balance control and postural stability in children with spastic hemiplegia
- Trial name
- BMPB-HCP (NCT07538297)
- Testing
- hemiplegic group, normal group
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- South Valley University
Spinal Muscular Atrophy (SMA)
Service Evaluation for Newborn Screening for Spinal Muscular Atrophy
Spinal Muscular Atrophy (SMA) is a disease that causes progressive muscle weakness. There are many types- the most severe and most common, type 1, affects very young babies, and is life-threatening if untreated.
- Trial name
- SENS (NCT07888868)
- Where
- 3 sites in United Kingdom
- Volunteers
- 750,000 people
- Sponsor
- University of Oxford
Recruitment
Chinese Regional Spinal Muscular Atrophy Patient Registration Study
The primary objectives of this study are to obtain clinically meaningful data on the survival, outcomes, prognosis and treatment effect of all the patients with spinal muscular atrophy (SMA) 5q types 1 to 3 (according to…
- Trial name
- NCT05631418
- Where
- China
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Hip Developmental Dysplasia
Effect of Cross-legged Sitting Among Patients With Unilateral Hip Developmental Dysplasia
One of the most common infant developmental diseases is Hip dysplasia which is mostly seen among female' babies and leads to hip instability due to partial or full hip dislocation [1].
- Trial name
- NCT07002840
- Testing
- Cross- legged sitting position, Physical Therapy Rehabilitation Program
- Volunteers
- 16 people
- Sponsor
- Jouf University
Graphomotor Impairment
Differences in Muscle Activity Patterns and Graphical Product Quality in Children With Graphomotor Impairment
Drawing on a vertical surface, rather than horizontal (such as blackboard) is often used by occupational therapists as a way of developing fine motor control and visual motor integration in children.
- Trial name
- NCT02501590
- Where
- 2 sites in Israel
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Loewenstein Hospital
Cerebral Palsy, Temporomandibular Disorder (TMD)
TMJ Dysfunction and Motor Severity in Children With CP
This study aims to examine the function of the temporomandibular joint (TMJ)-the jaw joint-in children with cerebral palsy (CP).
- Trial name
- NCT07043517
- Testing
- RDC/TMD
- Where
- Turkey (Türkiye)
- Volunteers
- 517 people
- Sponsor
- Istanbul Arel University
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor
Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Conditions
- Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Chordoma, Kidney Cancer
- Trial name
- NCT00003926
- Testing
- amifostine trihydrate, busulfan, filgrastim
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Chronic Pain, Spasticity, Muscle
Medtronic PSR TDD PMCF
The purpose of this study is to provide continuing evaluation and reporting of safety and performance of the SynchroMed II Infusion System within its intended use. Data will support post-market surveillance obligations.
- Trial name
- NCT04714385
- Where
- 15 sites in Belgium, Czechia and 6 more
- Volunteers
- 209 people
- Sponsor
- Medtronic
Cerebral Palsy, Spasticity
Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy
The aim of our work is to investigate whether electrical Lateral Cord Stimulation (LCS) causes an inhibitory and modulatory action by indirect cerebellar activation, so releasing spasticity and the spastic syndrome in selected…
- Trial name
- Andreani1 (NCT02199015)
- Testing
- Lateral spinal cord surgical implant of electrodes
- Where
- 2 sites in Argentina, Germany
- Volunteers
- 40 people
- Sponsor
- Juan Carlos M. Andreani MD
Pelvic Floor Disorders, Lower Urinary Tract Symptoms
Respiratory and Pelvic Floor Muscle Functions of Children With Lower Urinary Tract Dysfunction
Lower urinary tract dysfunctions (LUTD) are disorders that can occur in the storage and voiding stages of bladder function other than neurological disease or lower urinary tract obstruction.
- Conditions
- Pelvic Floor Disorders, Lower Urinary Tract Symptoms, Physical Activity
- Trial name
- NCT06728540
- Testing
- Investigation of Physical Activity Levels, Respiratory and Pelvic Floor Muscle Function
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Seda Yakit Yesilyurt
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Collecting and Storing Tissue From Young Patients With Cancer
This laboratory study is collecting and storing tissue, blood, and bone marrow samples from young patients with cancer. Collecting and storing samples of tissue, blood, and bone marrow from patients with cancer to study in the…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Central Nervous System Neoplasm, Ewing Sarcoma
- Trial name
- NCT00898755
- Testing
- Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
- Where
- 68 sites in United States, Canada
- Volunteers
- 213 people
- Sponsor
- Children's Oncology Group
Fatigue
Reliability of a Endurance and a Strength Test for Shoulder Rotation
Introduction: Verification of the progression of individuals submitted to training programs is performed by diagnostic tests with a focus on strength and muscular endurance.
- Trial name
- NCT03923608
- Testing
- Maximal muscle strength Test, Exhaustion test
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Stage IVB Adult Soft Tissue Sarcoma, Stage IIB Adult Soft Tissue Sarcoma
Isolated Limb Perfusion of Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Soft Tissue Sarcoma of the Arm or Leg
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Infusing melphalan directly to the tumor may kill more tumor cells and cause less damage to healthy tissues.
- Conditions
- Stage IVB Adult Soft Tissue Sarcoma, Stage IIB Adult Soft Tissue Sarcoma, Stage IIC Adult Soft Tissue Sarcoma, Recurrent Adult Soft Tissue Sarcoma
- Trial name
- NCT00019968
- Testing
- melphalan, tumor necrosis factor
- Sponsor
- National Institutes of Health Clinical Center (CC)
Temporomandibular Joint Disorder
Study of Etanercept and Celecoxib to Treat Temporomandibular Disorders (Painful Joint Conditions)
This 2-part study will evaluate the effectiveness and side effects of two anti-inflammatory drugs for relieving pain and improving jaw function in patients with temporomandibular disorder (TMD).
- Trial name
- NCT00001955
- Testing
- Etanercept, Celecoxib
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Muscle Spasticity
Randomized Controlled Trial of Virtual Reality
Measure pain and anxiety during a putative painful medical procedure (i.e., botulinum toxin injections) when Virtual Reality is employed compared to standard of care only using a Randomized Controlled Trial study design.
- Trial name
- NCT03521076
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Gillette Children's Specialty Healthcare
Neurofibromatosis 1 and 2 (NF1 and NF2)
A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)
Patients with clinically confirmed neurofibromatosis type 1 (NF1) or neurofibromatosis type 2 (NF2) or a known neurofibromatosis (NF) mutation aged 5 years and above will be eligible to participate and will be recruited from the…
- Trial name
- NCT03672838
- Testing
- hand-held dynamometer
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- NYU Langone Health
Mental Retardation, Body Composition, Beneficial
Resistance Training Program, Labor Inclusion, Intellectual Disability
Resistance exercise (RE) has been proposed as a possible strategy for prevention and rehabilitation of diseases. The increase in both muscle strength and the ability to perform tasks of day-to-day work environment and are…
- Conditions
- Mental Retardation, Body Composition, Beneficial, Muscle Weakness
- Trial name
- NCT01456910
- Testing
- Resistance Training Program
- Where
- 2 sites in Brazil
- Volunteers
- 40 people
- Sponsor
- University of Brasilia
Sarcopenia, COPD
Evaluate the Effect of Dietary Supplement Combined Exercise Among Patients With Sarcopenia Comorbid With Lung Disease
This trial is a prospective multi-center study. The purpose of this study is to evaluate the effect of dietary supplement combined with supervised exercised on the physical performance, body composition and lung function among…
- Conditions
- Sarcopenia, COPD, ILD
- Trial name
- NCT05926713
- Testing
- Sarcojoint®, supervised exercise
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Orient Europharma Co., Ltd.
Depressive Disorder, Fatigue Syndrome, Chronic
Glucocorticoid Effects on Cellular Cytokine Release
A variety of hormones and immune system processes are responsible for how the body responds to illness. This study concentrates on how the hormone cortisol effects the release of immune system factors called cytokines.
- Conditions
- Depressive Disorder, Fatigue Syndrome, Chronic, Fibromyalgia, Healthy
- Trial name
- NCT00001415
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Muscle Injury, Sprains and Strains
The Role of Periodic Health Examination in Determining Indirect Muscle Injury Risk in Elite Football (Soccer)
Preseason periodic health examination (PHE) is used routinely in elite football (soccer) and can be used to inform injury prevention strategies. Indirect muscle injuries (IMI) are a considerable burden to elite teams.
- Trial name
- NCT03782389
- Testing
- Preseason Periodic Health Examination Completion
- Volunteers
- 321 people
- Sponsor
- Manchester United Football Club
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