Clinical trials: Myopia Progression
Myopia
The Contact Lens and Myopia Progression (CLAMP) Study
To examine the effects of rigid gas permeable contact lenses on the progression of myopia (nearsightedness) in children To determine what changes in the eyes cause certain eyes to progress in nearsightedness more slowly
- Trial name
- NCT00009529
- Where
- United States
- Sponsor
- National Eye Institute (NEI)
High Myopia
The Effect and Safety of Different Doses of Atropine on Myopic Progression of Highly Myopic Children: Multi-centered Randomized Clinical Trial
Objective: to evaluate the efficacy of different concentrations of atropine eye drops in controlling the progression (diopter, axial length) of high myopia in young children, and to compare the compliance, adverse reaction and…
- Trial name
- NCT04699357
- Testing
- Atropine
- Where
- 3 sites in China
- Volunteers
- 219 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Refractive Error - Myopia
Minimum Power and Frequency of Repeated Low-level Red-light to Effectively Control Myopia Progression
To explore the minimum power and frequency of Repeated Low-level Red-light (RLRL) to control myopia progression in low-myopic children aged 8-10 years, and the rebound effect of low-myopic children after discontinuation of RLRL…
- Conditions
- Myopia, Refractive Error - Myopia, Choroidal Thickness, Retina
- Trial name
- NCT06717048
- Testing
- Repeated Low-level Red-light, Red LED
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Myopia, Progressive
Kubota Glass Parameter Refinement Study
Length of the eye will be measured in subjects exposed to various stimulus characteristics using an electronic spectacle which presents illuminated targets to the eye.
- Conditions
- Myopia, Myopia, Progressive, Vision Disorders
- Trial name
- NCT06085430
- Testing
- Kubota Glass
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Myopia, Myopia Progression
Evaluation of Performance of MiYOSMART Photochromic and Clear Spectacle Lenses in Myopic Children
This clinical study aims to evaluate the non-inferiority of the photochromic DIMS spectacles lenses performance (PDIMS) compared to clear DIMS spectacles lenses (DIMS) in myopia management.
- Trial name
- PDIMS (NCT06717035)
- Testing
- EYE001
- Where
- Singapore
- Volunteers
- 202 people
- Sponsor
- Singapore National Eye Centre
Myopia
Discontinuation of Lens Wear in New Ortho-k Children (DOEE2)
This study aims at investigating the efficacy of myopic control using ortho-k in younger and older children.
- Trial name
- DOEE2 (NCT01236755)
- Testing
- single-vision glasses, ortho-k lenses
- Where
- China
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Association of Genetic Variants With Myopia
This study aims to identify genetic factors linked to myopia, including those that influence a person's risk of developing it and how quickly it progresses (like changes in eye length).
- Trial name
- NCT07030153
- Testing
- Oral swab DNA analyzed for myopia-related gene variants
- Where
- 2 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Visionly Plus Eye Hospital
Myopia
Evaluation of the Efficacy in Decreasing Myopia Progression of the Proposed Ophthalmic Lens Prototypes
Evaluation of the efficacy in decreasing myopia progression of the proposed ophthalmic lens prototypes.
- Trial name
- NCT05250206
- Testing
- Myopia control lens
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Indizen Optical Technologies, S.L.U.
Myopia Progression
Orthokeratology Lens Decentration with Two Designs of Corneal Refractive Therapy™ Lenses: a One-year Prospective Study
Background/Objectives: To examine the trend of treatment zone (TZ) decentration over 12 months of Orthokeratology (OK) wear using two corneal refractive therapy (CRT) lens designs: standard (STD) and dual axis (DA).
- Trial name
- NCT06726499
- Testing
- Spherical CRT, Toric CRT
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Myopia
A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children
A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children
- Trial name
- NCT06305663
- Testing
- Bausch + Lomb (kalifilcon A) Myopia Control Soft (Hydrophilic), CooperVision MiSight (omafilcon A/60%) Myopia Control one day Soft Contact Lens
- Where
- 11 sites in China
- Volunteers
- 418 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia (Disorder), Astigmatism
Optical Quality of the Cornea in Orthokeratology
Analyzing Optical Quality After the Use of Overnight Orthokeratology (Ortho-K)
- Trial name
- COPCORTO (NCT06775509)
- Testing
- Ortho-K
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Children With Myopia, Treatment
Clinical Study on the Effectiveness of Diverse Segments Defocus Optimization in Spectacle Lenses for Slowing Myopia Progression
Clinical Trial The goal of this clinical trial is to evaluate the effectiveness of two types of Diverse Segments Defocus Optimization (D.S.D.O.) spectacle lenses in slowing myopia progression in children.
- Conditions
- Children With Myopia, Treatment, Multizone Lens Design for Myopic Defocus, Visual Quality
- Trial name
- NCT07323251
- Testing
- Diverse Segments Defocus Optimization (D.S.D.O.) spectacle lenses
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Effectiveness of 0.01% Atropine Sulfate Solution in Controlling of Myopia Progression in Children
Increasing number of myopic children and significant complications of high myopia enhance the necessity of effective control strategy.
- Trial name
- NCT04338373
- Testing
- 0.01% Atropine sulfate solution in "Comfort Drops" ("AVIZOR S.A.", Spain)
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- The V.P. Vyhodcev Eye Hospital
Intermittent Exotropia, Myopia Overcorrection
Overminus Lens Therapy in Intermittent
In this prospective study, entitled "The Long-Term Efficacy of Overminus Lens Therapy in Intermittent Exotropia",the investigators examined the long-term impact of overminus lenses on the management of intermittent exotropia…
- Conditions
- Intermittent Exotropia, Myopia Overcorrection, Over-minus Therapy, Myopia Progression
- Trial name
- NCT03952702
- Testing
- Myopic overcorrection
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ege University
Myopia
Impact of Electronic Devices on Myopia Development and Progression
The aim of the stuy is to investigate the effects of the adoption of a curriculum with electronic devices for teaching materials and textbooks in Hong Kong schoolchildren on their changes in refractive error and visual function.
- Trial name
- NCT02150421
- Where
- China
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
High Myopia
SmoothCore Orthokeratology Plus M.O.V.E. Lenses vs. M.O.V.E. Lenses Alone for Myopia Control in Children With High Myopia
This clinical trial aims to determine whether a combination of overnight orthokeratology lenses and daytime myopia-control spectacles is more effective than myopia-control spectacles alone in slowing myopia progression and…
- Trial name
- NCT07854366
- Testing
- SmoothCore Technology Orthokeratology Combined with M.O.V.E. Lenses, M.O.V.E. Lenses Alone
- Volunteers
- 100 people
- Sponsor
- Beijing Tongren Hospital
Myopia, Orthokeratology
Effectiveness of Myopia Control by Breath-O Correct Orthokeratology Lenses
This is a 24-month longitudinal randomized controlled trial aiming to evaluate the effectiveness of myopia control by Breath-O correct orthokeratology lenses in different myopia progression groups classified according to their…
- Trial name
- NCT03919396
- Testing
- Breath-O orthokeratology lenses
- Where
- Hong Kong
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
Myopia Control With a Innovative Spectacle Lens
The purpose of this study is to demonstrate that the test spectacle lens is safe and effective in slowing myopia progression in children.
- Trial name
- NCT05174780
- Testing
- innovative myopia control spectacle lens, Single vision spectacle lens
- Where
- 9 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Juvenile Myopia
Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens
This is a conventional efficacy trial to validate the results from previous clinical trials for younger children; the 12-month efficacy results will be used to predict the 3-year treatment efficacy.
- Conditions
- Myopia, Juvenile Myopia, Myopia Progression
- Trial name
- EUCALYPTUS (NCT06034327)
- Testing
- Single vision, impact-resistant spectacle lenses; Test Arm, Single vision, impact-resistant spectacle lenses; Control Arm
- Where
- 14 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
Controlling Myopia Progression With Soft Contact Lenses
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression.
- Trial name
- NCT01787760
- Testing
- Test Soft Contact Lens B, Test Soft Contact Lens C, Active Comparator
- Where
- Hong Kong
- Volunteers
- 221 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.