Clinical trials: Near Vision
Developmental Coordination Disorder
Effects of Acute Exercise on Motor Learning and Brain Activity in Children With DCD
The aim of this study is to investigate the impact of an acute intense physical exercise bout on the learning ability of children with typical motor development (TD) and children with developmental coordination disorder (DCD).
- Trial name
- ExLeBrainDCD (NCT05936372)
- Testing
- Acute intense aerobic exercise
- Where
- 3 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut Nacional d'Educacio Fisica de Catalunya
High Myopia
Screening and Identification of Biomarkers for High Myopia by a Rapid Method
To screen and identify sensitive biomarkers for high myopia via a robust, convenient, and cost-effective approach according to the association between high myopia and concentration of biomarkers in tear fluid, saliva and blood…
- Trial name
- NCT05803174
- Testing
- blood sample
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia, Dental Caries
Bedtime Routines and Children's Health
In Taiwan, the prevalence of sleep problems, myopia, and dental caries in school-age children is high. Little is known regarding the implementation of oral and vision health outcomes around bedtime.
- Conditions
- Myopia, Dental Caries, Sleep, Asthenopia
- Trial name
- NCT05201924
- Testing
- Bedtime routine, Control
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
Cutaneous Metastatic Melanoma
Intratumoral Targeted Hyperthermia Therapy (THT) for Cutaneous Metastatic Melanoma
This device phase I/II, first in human, early feasibility study (EFS), open-label, single-arm trial aims to evaluate the safety, tolerability, and preliminary efficacy of Gold Nanorod (GNR)-enabled sub-ablative targeted…
- Trial name
- NCT06870994
- Testing
- Targeted Hyperthermia Therapy
- Volunteers
- 10 people
- Sponsor
- Sona Nanotech Inc
Myopia
Comparing a Monthly Replacement Lens Versus a Daily Disposable Lens
The purpose of this study was to compare subjective ratings of lens handling at insertion for a monthly replacement lens versus a daily disposable lens in habitual soft lens wearers.
- Trial name
- NCT06046209
- Testing
- Control Lens, Test Lens
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Myopia
Myopia Prevalence in Canadian School Children - a Pilot Study
The goal of this study is to determine the prevalence of nearsightedness in Canadian school children living in the Waterloo Region.
- Trial name
- Falcon (NCT01942057)
- Where
- Canada
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia, Light; Therapy, Complications
Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)
The goal of this clinical trial is to evaluate whether the optimization of daily exposure to light in primary school children can lead to better myopia prevention and control.
- Conditions
- Myopia, Light; Therapy, Complications, Myopia Progression, Short-Sighted
- Trial name
- LightSPAN (NCT06631339)
- Testing
- Light Intervention, Digital Intervention, Control Group
- Where
- 5 sites in Singapore
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Myopia, Child Myopia Progression
Effect of MiYOSMART iQ Spectacle Lenses on Myopia Progression in Children
This prospective, single-center study aims to evaluate the efficacy and safety of MiYOSMART iQ spectacle lenses with DIMS (Defocus Incorporated Multiple Segments) and Triple Enhanced Design (TED) technology in slowing myopia…
- Trial name
- NCT07387159
- Testing
- MiYOSMART iQ spectacle lenses
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Hoya Lens Rus LLC
Congenital Cataract
Guangke Lenses in Congenital Cataract
This study aims to investigate whether individually customized bifocal + defocus spectacles can slow myopic shift in children after congenital cataract surgery.
- Trial name
- NCT07778797
- Testing
- Conventional Bifocal Lenses, Individually Customized Bifocal + Defocus Lenses
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Neonatal Jaundice
Efficacy of Zinc in Reducing Hyperbilirubinemia Among High Risk Neonates - A Double Blind Randomized Trial
The purpose of this study is to determine the effect of 10 mg of oral zinc given daily between days 2 and 7 of life to term or near term neonates with serum bilirubin levels of more than 6 mg/dL at 24 ± 6 hours of life on…
- Trial name
- NCT00692224
- Testing
- zinc gluconate
- Where
- India
- Volunteers
- 294 people
- Sponsor
- All India Institute of Medical Sciences
Myopia
SEED-LVPEI Myopia Study
This randomized clinical trial study aims to investigate the efficacy of novel SEED's EDOF based mid-lens design in controlling the myopia progression in Indian children with these specific objectives: 1.
- Trial name
- SLIMS (NCT04618510)
- Testing
- SEED 1-dayPure EDOF soft contact lens, Single Vision Spectacles
- Where
- India
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- L.V. Prasad Eye Institute
Myopia Progressing, Childhood
Topical 0.01% Atropine for the Control of Fast Progressing Myopia
Myopia prevalence has dramatically increased worldwide in recent years in the general population and among children. Progressive myopia increases gradually with growth until the age of 20-25 years.
- Trial name
- Myopie-STOP (NCT04173780)
- Testing
- Atropine 0.01%
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Myopia
The Role of SNP of ECM and MMP on the Development of Pathological High Myopia
To study the clinical characteristics and inheritance of pathological myopia in Taiwanese patients.
- Trial name
- NCT00172952
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diagnostic Test, NIRS
Near Infrared Spectroscopy and Testicular Torsion in Children
NIRS estimates tissue saturation of oxygenation in tissue beds. Animals studies suggested that transscrotal NIRS measurements can quantify testicular hypoxia and differentiate between torsed and non torsed testicles.
- Conditions
- Diagnostic Test, NIRS, Testicular Torsion, Diagnosis
- Trial name
- SPIRETTE (NCT05769244)
- Testing
- near-infrared spectroscopy (NIRS)
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Transient Tachypnea of the Newborn
Positive End Expiratory Pressure With A T-piece Resuscitator For Near-Term and Term Infants With Respiratory Distress
Evaluating the effect of early application of Continuous positive airway pressure (CPAP) via Neopuff in cases of transient tachypnea of the newborn(TTN) and its role in decreasing the duration and complication of TTN.
- Trial name
- NCT01859533
- Testing
- Neopuff
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Major Depressive Disorder
The Effect of Intradermal Acupuncture on Gallbladder Meridian Points on Cerebral Hemodynamics in Relevant Brain Regions for Major Depressive Disorder Based on fNIRS Technology
Gallbladder meridian(GB) acupoints may play an important role in the treatment of major depressive disorder (MDD). Therefore, this study is designed to focus on the traditional Chinese medicine (TCM) theory of " gallbladder…
- Trial name
- NCT05707299
- Testing
- Intradermal acupuncture
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Myopia
Orthokeratology and 0.01% Atropine Sequential Treatment for Myopia Control
The purpose of this multicenter randomized clinical trial is to evaluate the myopia control effect of orthokeratology and 0.01% atropine sequential treatment in children and adolescents, as compared to continuous treatment with…
- Trial name
- NCT06667037
- Testing
- Ortho-k lenses, 0.01% Atropine
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Daily Disposable Comparison Study
The objective of the study is to compare the overall subjective preference between two Daily Disposable hydrogel lenses when refitted into a third hydrogel lens.
- Trial name
- NCT02094677
- Testing
- filcon II 3, etafilcon A, nelfilcon A
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
Toric Orthokeratology - Slowing Eye Elongation
The aims of this study are to investigate the effects of ortho-k for astigmatic and myopic reduction and myopic control in children, and the long term effects on corneal curvatures and biomechanics.
- Trial name
- TO-SEE (NCT00978692)
- Testing
- Toric Orthokeratology lenses, Single-vision spectacles
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Visual Acuity
Evaluating Accommodative Responses of Soft Contact Lenses for Myopia Control
This is a bilateral, non-dispensing, randomized, controlled, double-masked, 7x7 cross-over study. Each subject will be bilaterally fitted with one of the 7 test articles in each of the 7 periods for a total of four visits.
- Trial name
- NCT03635528
- Testing
- Test Lens 1, Test Lens 2, Test Lens 3
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.