Clinical trials: Near-Infrared Spectroscopy
Hypoxic-Ischemic Encephalopathy, Congenital Heart Disease
Evaluating a Wireless NIRS Device in the Neonatal Intensive Care Unit
The wireless NIRS sensor will be placed on the participant's forehead, directly underneath the INVOS wired sensor. The wireless NIRS sensor will remain in place for 4 consecutive hours, over 2 consecutive days.
- Conditions
- Hypoxic-Ischemic Encephalopathy, Congenital Heart Disease, Stroke Hemorrhagic, Aneurysm Cerebral
- Trial name
- NCT07732244
- Testing
- Wireless NIRS
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Preterm Infant, Music
The Effects of Music Therapy on Near-infrared Spectroscopy and Electroencephalogram in Premature Infants
Music has been consistently shown magic power in brain plasticity. Several study proved music can influence electronic activity of preterm infants' brain, while none study covered region oxygen metabolic.
- Conditions
- Preterm Infant, Music, Near-infrared Spectroscopy, Electroencephalogram
- Trial name
- NCT04009655
- Testing
- music
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Children's Hospital of Fudan University
ADHD
fNIRS Neurofeedback Training Using Virtual Reality in Children With ADHD
The study aims to explore the effectiveness of neurofeedback training on improving attention and inhibitory control of children with attention-deficit/hyperactivity disorder (ADHD) in Hong Kong.
- Trial name
- NCT05906485
- Testing
- fNIRS Neurofeedback-VR Training, Computerized Cognitive Training
- Where
- Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Respiratory Distress Syndrome, Prematurity
The Effect of Surfactant Administration on Cerebral Oxygenation
The purpose of this study is to assess changes in cerebral oxygenation during two different types (beractant and poractant) and two different routes (double lumen or single lumen endotracheal tube) of surfactant administration…
- Trial name
- NCT01258517
- Testing
- near infrared spectroscopy (INVOS 5100)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Placenta Diseases
Near-infrared Spectroscopy: Differences in Placental Oxygenation in Relation to Ultrasound Maturation Grade in physiologIcal Term Pregnancies
The aim was to compare placental oxygenation in low risk, uncompli-cated, term pregnancies measured by near-infrared spectroscopy (NIRS) in relation to the placental maturity grade determined by ultrasound assessment according to…
- Trial name
- NCT05771415
- Where
- Croatia
- Volunteers
- 34 people
- Sponsor
- University of Palermo
Congenital Heart Disease
NIRS Predict Low Cardiac Output State in Neonates and Infants in Cardiac Surgery
Neonates and infants that have cardiac surgery with cardiopulmonary bypass (CPB) for congenital heart disease are at great risk for experiencing life-threatening low cardiac output syndrome (LCOS) in the first 24 hours after…
- Trial name
- NCT01849120
- Testing
- EQUANOX Advance 8004CB sensor
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Mayo Clinic
Congenital Heart Defects
Near Infrared Spectroscopy in Cyanotic Congenital Heart Disease
We are conducting a prospective cohort study of 20 children with cyanotic congenital heart disease who are admitted for cardiac surgery.
- Trial name
- NCT02417259
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital
Autism Spectrum Disorder (ASD)
Expression Intensity Modulates Social Intention Understanding in ASD Children
Children watch videos of a single model playing with toys, judge whether the model desires a new toy based on observing the model's varying expression intensities, and form a judgment on whether the model intends to obtain a new…
- Trial name
- NCT07884032
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Syncope
Multi-Site Near Infrared Spectroscopy (NIRS) Monitoring of Children During Tilt Table Testing
PURPOSE OF THE STUDY This study will explore the use of multi-site NIRS monitoring during tilt table testing, combining somatic and cerebral saturations data with hemodynamic data to establish the non-invasive assessment of…
- Trial name
- NIRS & Tilt (NCT00659464)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Juvenile Neuronal Ceroid Lipofuscinosis, Smith-Lemli-Opitz Syndrome
Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls
Background: Neurocognitive disorders affect how the brain uses oxygen. They may affect mental development in children. These disorders can be studied with imaging scans that use radiation; however, these methods are not ideal for…
- Conditions
- Juvenile Neuronal Ceroid Lipofuscinosis, Smith-Lemli-Opitz Syndrome, Creatine Transporter Deficiency, Niemann-Pick Disease Type C1
- Trial name
- NCT05642221
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Arterial Hypotension, Shock
Cerebral Circulation in Critically Ill Children
The principal purpose of this study is to describe the changes in cerebral circulation (assessed by transcranial ultrasound) and oxygenation (assessed by Near InfraRed spectroscopy, NIRS) during resuscitation for hemodynamic…
- Conditions
- Arterial Hypotension, Shock, Cerebral Lesion
- Trial name
- CIRCU-REAPED (NCT03731104)
- Testing
- Near InfraRed Spectroscopy assessment, Transcranial Doppler Ultrasound assessment, Cardiac output assessment
- Where
- 3 sites in France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ADHD - Attention Deficit Disorder With Hyperactivity
Brain Stimulation and Attention Control in Children With ADHD
The goal of this clinical trial is to learn if brain stimulation can help children ages 6 to 12 with attention-deficit/hyperactivity disorder (ADHD) improve their attention and self-control.
- Trial name
- NCT07182344
- Testing
- Intermittent Theta Burst Stimulation to Right DLPFC
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Neurolab Plus
Cardiac Failure
Near Infrared Spectroscopy (NIRS) for Heart Failure Assessment.
It is routine practice for a cardiologist to perform a battery of tests to assess the degree of heart failure. The purpose of this study is to establish a non-invasive method to reliably predict cardiac output state in real-time…
- Trial name
- NCT01577810
- Testing
- Near Infrared Spectroscopy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Phoenix Children's Hospital
Blood Pressure
The Newborn Project: Examining the Oxygenation of Brain Tissue During General Anesthesia
This study will be an observational, prospective trial that will measure the cerebral oxygenation of infants scheduled to undergo general anesthesia at Boston Children's Hospital.
- Trial name
- NCT03057587
- Testing
- NIRS Monitoring
- Where
- United States
- Sponsor
- Boston Children's Hospital
Cardiac Catheterization
Validation of Brain Oxygenation Monitor on Pediatric Patients
The aim of this study is calibrate (adjust and tune) the CAS FORE-SIGHT Near-Infrared Spectroscopy (NIRS) monitor when used to measure the tissue oxygen saturation of internal organs (StO2).
- Trial name
- NCT00849940
- Testing
- CAS NIRS FORE-SIGHT oximeter
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Duke University
Acute Kidney Injury, Hypoxia-Ischemia, Brain
Tissue Oxygenation During Treatment of Infant Congenital Heart Defects
Background: Acute kidney injury (AKI) is a common and serious postoperative complication in children with congenital heart disease.
- Conditions
- Acute Kidney Injury, Hypoxia-Ischemia, Brain, Mesenteric Ischemia
- Trial name
- NCT03941015
- Where
- China
- Volunteers
- 245 people
- Sponsor
- Beijing Anzhen Hospital
Child, Only, Inhalation; Vapor
Cerebral and Peripheral Near Infrared Spectroscopy Monitoring in Low and High Flow Anaesthesia in Pediatric
To investigate the effects of non-invasive cerebral and peripheral NIRS monitoring and low and high flow sevoflurane anaesthesia on cerebral and peripheral NIRS in paediatric patients.
- Conditions
- Child, Only, Inhalation; Vapor, Anesthesia, Cerebral Oxygenation
- Trial name
- NCT06320743
- Testing
- NIRS ,Ventilation parameters, Oxygen concentration
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara City Hospital Bilkent
Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder
Near Infrared Spectroscopy in Children With Autism and ADHD
Background: Near-infrared spectroscopy (NIRS) is a functional imaging technique that can be uses light to study brain function while allowing for movement.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder, Autism
- Trial name
- NCT01730079
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Intermittent Hypoxemia, Apnea of Prematurity
Influence of Oxygen Target Range on Intermittent Hypoxemia in Preterm Infants
In this randomized crossover trial, preterm infants with intermittent hypoxemia and need for supplemental oxygen will be randomized to either Sequence of two different oxygen target ranges (low: 85-89%; high: 91-95%) for a total…
- Trial name
- NCT02743988
- Testing
- Oxygen
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University of Ulm
Testicular Torsion, Healthy
Light-Based Monitoring (SR-NIRS) for Suspected Testicular Torsion in Children
The goal of this clinical trial is to learn whether a non-invasive light-based test called Spatially Resolved Near-Infrared Spectroscopy (SR-NIRS) can measure blood flow and oxygen levels in the testicles of children.
- Trial name
- SR-NIRS (NCT07548086)
- Testing
- SR-NIRS
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- Kourosh Afshar