Clinical trials: Neglect
Malaria Transmission
Assessing the Effect of Neglected Tropical Diseases on Plasmodium Falciparum Transmission in an Area of Co-endemicity
Assessing the effect of neglected tropical diseases on Plasmodium falciparum transmission in an area of co endemicity.
- Trial name
- TRANSMAL (NCT02769013)
- Testing
- Pre-treatment follow up, S. haematobium treatment, Post treatment follow up
- Where
- 2 sites in Gabon, Ghana
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Child Development, Child Behavior
Catholic Health Initiatives (CHI) St. Joseph's Children Home Visiting Longitudinal Study
This study involves a long-term outcome study of the Catholic Health Initiative St. Joseph's Children (CHI SJC) program using a randomized control study.
- Conditions
- Child Development, Child Behavior, Child Abuse, Child Neglect
- Trial name
- NCT05729945
- Testing
- home visiting
- Where
- United States
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Child Abuse
A Medical Home-Based Intervention to Prevent Child Neglect in High-Risk Families
Child maltreatment, particularly neglect, disproportionally affects low-income children with special health care needs (CSHCN) and has serious short and long-term consequences.
- Trial name
- NCT02857673
- Testing
- Child Abuse Prevention Problem Solving, Active Control Group
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Medical Center
Cartilage Injury, Orthopedic Disorder
CAsting and REhabilitation Versus Supervised Neglect for Osteochondral Lesions of the Talus in the Pediatric Population
Rationale: OCLs (osteochondral lesions) of the talus can be congenital or can occur after trauma or in patients with juvenile idiopathic arthritis (JIA). The main complaint of an OCL is pain during weightbearing activities.
- Conditions
- Cartilage Injury, Orthopedic Disorder, Skeletal Injury, Rehabilitation
- Trial name
- CARE (NCT06220539)
- Testing
- Casting and supervised rehabilitation
- Where
- 2 sites in Netherlands
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Tristan Buck
Child Neglect, Internalizing Disorder
Child and Parent-directed Individualized Psychotherapy (CPIP)
With CPIP the investigators opt for a manualized modular psychotherapy designed especially to meet the needs of children with internalizing disorders that suffered or still suffer from emotional or physiological neglect.
- Trial name
- AMIS-II-RCT (NCT05128669)
- Testing
- CPIP, ECS
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- University of Leipzig
Child Maltreatment, Interpersonal Relations
Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents
The goal of this clinical trial is to investigate how the friendship experiences of maltreated (i.e., abused and/or neglected) and non-maltreated adolescents differentially influence their risk for adverse outcomes.
- Conditions
- Child Maltreatment, Interpersonal Relations, Victimisation, Psychopathology
- Trial name
- BFFs (NCT05893459)
- Testing
- Debrief
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Emotion Regulation, Emotional Neglect
How do You Feelee? Emotion-based Smartphone App in the Forensic Outpatient Setting
This intervention study aims to explore the addition of the Feelee app (using active emoji data with passive behavioral data through phone sensing) in treatment as usual for adolescents in the forensic outpatient setting.
- Trial name
- NCT06509360
- Testing
- Feelee app
- Where
- 2 sites in Netherlands
- Volunteers
- 24 people
- Sponsor
- Amsterdam UMC, location VUmc
Leprosy, Buruli Ulcer
Integrated Mapping of Skin-presenting Neglected Tropical Diseases in Liberia
Appropriate targeting of interventions for neglected tropical diseases (NTDs) that require innovative and intensified disease management (IDM) requires accurate data on the distribution of these diseases within endemic countries.
- Conditions
- Leprosy, Buruli Ulcer, Yaws, Lymphatic Filariases
- Trial name
- NCT03683745
- Where
- Liberia
- Volunteers
- 56,285 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Rabies in Animals, Worms; Intestine
Integrating Community Interventions to Eliminate Neglected Tropical Diseases
The overarching goal of this project is the elimination of two neglected tropical diseases (NTD): soil-transmitted helminthiasis and rabies.
- Trial name
- NCT03667079
- Testing
- integrated delivery of deworming and vaccination, Mass deworming only, Mass vaccination of dogs
- Where
- United States
- Volunteers
- 28,143 people, healthy volunteers welcome
- Sponsor
- Washington State University
S. Aureus Oropharyngeal Colonization
Decolonization of the Oropharynx, an Important and Neglected Reservoir of S. Aureus Colonization
The problem of interest is the high rate of recurrent SSTIs in children caused by S. aureus despite the use of systemic antibiotic treatment, due to difficulties in decolonization and the prevalence of antibiotic-resistant…
- Trial name
- NCT02589067
- Testing
- Chlorhexidine gluconate
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Chronic Chagas
Prospective Evaluation of Rapid Diagnostic Tests for Trypanosoma Cruzi Infection
Chagas disease (CD) is the most significant endemic zoonosis in Argentina. Two-thirds of affected individuals live in urban areas but only 10% globally are aware of their infection.
- Trial name
- NCT07304349
- Where
- 4 sites in Argentina
- Volunteers
- 3,234 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Parasitologia Dr. Mario Fatala Chaben
Neglect, Child, Non-Accidental Trauma
Supervisory Neglect, Non-Accidental Trauma, Brief Intervention, and Treatment Referral
The Supervisory Neglect, Non-Accidental Trauma, Brief Intervention, and Treatment Referral (SunBrite) protocol is a family-empowered, risk mitigation strategy that targets families with young children who present to the ED with…
- Conditions
- Neglect, Child, Non-Accidental Trauma, Non-Accidental Injury to Child, Head Trauma
- Trial name
- SunBrite (NCT03704272)
- Testing
- SunBrite
- Sponsor
- Phoenix Children's Hospital
Prostate Cancer
Prevalence of Neglected Side Effects to Radical Prostatectomy
The purpose of this exploratory data collection is to strengthen our knowledge of some of the rarer distresses following surgical removal of the prostate.
- Trial name
- NCT01742962
- Testing
- Radical prostatectomy for prostate cancer
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Copenhagen University Hospital at Herlev
Child Neglect
Effectiveness Trial for Project SafeCare for Child Neglect
The study is a field trial comparing the SafeCare family preservation model to a comparable usual care model for parents in child welfare. The study also compares two levels of service quality control.
- Trial name
- NCT01391754
- Testing
- SafeCare, In vivo coached quality control, Services As Usual
- Where
- 3 sites in United States
- Volunteers
- 2,175 people
- Sponsor
- University of Oklahoma
Conduct Disorder, ADHD
Intervening Early With Neglected Children
This study will assess early and middle childhood outcomes of an intervention for neglecting parents that was implemented in the children's infancy.
- Conditions
- Conduct Disorder, ADHD, Depression
- Trial name
- NCT02093052
- Testing
- Attachment and Biobehavioral Catch-up, Developmental Education for Families
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Delaware
Malaria,Falciparum, Neglected Tropical Diseases
Adjunctive Ivermectin Mass Drug Administration for Malaria Control
This is a cluster-randomized placebo-controlled clinical trial to evaluate the additive benefit of Ivermectin (IVM) (or Placebo) mass drug administration (MDA) to dihydroartemisinin-piperaquine (DP) MDA for malaria control in a…
- Conditions
- Malaria,Falciparum, Neglected Tropical Diseases, Strongyloidiasis, Lymphatic Filariasis
- Trial name
- MATAMAL (NCT04844905)
- Testing
- Ivermectin, Dihydroartemisinin-piperaquine
- Where
- Guinea-Bissau
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Unspecified Child Maltreatment, Suspected, Unspecified Child Maltreatment, Confirmed
Northwell Health Visits: A Family Connects Pilot Implementation at Northwell Health
Northwell Health Visits (NHV) is a three year pilot replication of the evidence-based model, Family Connects, which is a brief universal Nurse Practitioner home visiting program for new mothers and their infants.
- Conditions
- Unspecified Child Maltreatment, Suspected, Unspecified Child Maltreatment, Confirmed, Postpartum Depression
- Trial name
- NCT03887910
- Testing
- Enhanced Intervention, Intervention
- Where
- United States
- Volunteers
- 840 people
- Sponsor
- Northwell Health
Onchocerciasis (River Blindness), Schistosomiasis
Expanding Access to Preventive Chemotherapy Among Mobile and Migrant Populations
Neglected Tropical Diseases (NTDs) are among the most common groups of diseases affecting over one billion people globally and are disproportionately concentrated in remote, underserved, and marginalized communities.
- Conditions
- Onchocerciasis (River Blindness), Schistosomiasis, Soil Transmitted Helminth (STH) Infections, Lymphatic Filariasis
- Trial name
- MISSION (NCT07707817)
- Testing
- Modified Mass Administration of Medicines Strategy, Albendazole 400 mg, Praziquantel 40 mg/kg
- Where
- Nigeria
- Volunteers
- 5,760 people, healthy volunteers welcome
- Sponsor
- Uwemedimo Friday Ekpo
Foreign Body; Inhalation
Presentation And Management Of Neglected Inhaled Foreign Body At Sohag University Hospital
Delayed presentation is not uncommon in children and may have been treated as asthma due to associated with low-grade cough and noisy breathing.
- Trial name
- NCT04988113
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University