Clinical trials: Neonatal Mortality
Patients Who Underwent Surgery for Congenital Heart Disease
Influence of Tidal Volume During Mechanical Ventilation on Postoperative Clinical Outcome in Pediatric Patients Undergoing Congenital Heart Surgery
High tidal volume during mechanical ventilation has been reported to increase mortality in patients with acute lung injury or acute respiratory distress syndrome.
- Trial name
- NCT02081274
- Testing
- Surgery for congenital heart disease
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Samsung Medical Center
Maternal; Procedure
Total Placenta Previa Associated With the Placenta Accreta Spectrum.
To assess the reliability of placental magnetic resonance imaging measurements in predicting peripartum hysterectomy and neonatal outcomes in patients with total placenta previa.
- Trial name
- PAS (NCT06219564)
- Testing
- Peripartum total abdominal hysterectomy (p-TAH), Cesarean Section (C/S), Neonatal mortality
- Where
- Turkey (Türkiye)
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Bacterial Vaginosis, Fetal Membranes, Premature Rupture
Perinatal Infections in Pakistan
There are large differences in health outcomes related to pregnancy and birth between developed and developing countries. This study will investigate how infections, medical history, health care behavior and psychosocial issues…
- Conditions
- Bacterial Vaginosis, Fetal Membranes, Premature Rupture, Chorioamnionitis, Pregnancy
- Trial name
- NCT00070746
- Where
- Pakistan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Mortality Through Six Months of Age, Vitamin A Deficiency
Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural Bangladesh
The purpose of this trial is determine whether a 50,000 IU oral dose of vitamin A delivered to newborn infants within the first days of life, reduces six-month infant mortality by at least 15%.
- Trial name
- NCT00128557
- Testing
- vitamin A supplementation (15,000 ug retinol equivalents or 50,000 IU)
- Where
- Bangladesh
- Volunteers
- 15,937 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Premature Birth, Mortality
Trial to Evaluate a Specified Type of Apgar (TEST-APGAR) Follow Up Study
A specified version of the Apgar-Score, that can be used in newborns under resuscitation, was developed and its value to predict chronic damage in preterm infants will be tested.
- Conditions
- Premature Birth, Mortality, Apgar Score
- Trial name
- NCT01186627
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- Technische Universität Dresden
Perinatal Morbidity, Morbidity;Perinatal
Multicentric Retrospective Study of Perinatal Mortality
Background: Perinatal mortality ranges mortality from 22 gestational weeks up to the first 7 days of life and extended mortality goes up to 28 days of life.
- Conditions
- Perinatal Morbidity, Morbidity;Perinatal, Stillbirth, ICD
- Trial name
- PM-PHD-NTM (NCT05491772)
- Where
- Spain
- Volunteers
- 468 people
- Sponsor
- Corporacion Parc Tauli
Gastroschisis, Anorectal Malformation
Children's Surgery in Sub-Saharan Africa
Background: Five billion people worldwide do not have access to safe, affordable surgical care. A significant proportion live in sub-Saharan Africa (SSA), where up to 50% of the population are children.
- Conditions
- Gastroschisis, Anorectal Malformation, Appendicitis, Intussusception
- Trial name
- PaedSurgAfrica (NCT03185637)
- Testing
- Various interventions for each of the conditions.
- Where
- United Kingdom
- Volunteers
- 1,407 people
- Sponsor
- King's College London
Acute Respiratory Tract Infections, Diarrhea
Home Based Child Care to Reduce Mortality and Malnutrition in Tribal Children of Melghat, India: CRCT
Melghat is poorly developed tribal area in India with very high child mortality \& malnutrition prevalence (grossly inadequate medical facilities). Important health problems.
- Conditions
- Acute Respiratory Tract Infections, Diarrhea, Malaria, Neonatal Sepsis
- Trial name
- HBCC (NCT02473796)
- Testing
- Home based child care
- Where
- India
- Volunteers
- 7,594 people
- Sponsor
- MAHAN Trust
Prenatal Care
Group Antenatal Care: The Power of Peers for Increasing Skilled Birth Attendance in Achham, Nepal
In rural Nepal, the major drivers of underutilization of skilled birth attendance are poverty, poor social support and inadequate birth planning.
- Trial name
- NCT02330887
- Testing
- Group Antenatal Care, Individual Antenatal Care
- Where
- Nepal
- Volunteers
- 2,184 people, healthy volunteers welcome
- Sponsor
- Possible
Neonatal Mortality
Ghana Newborn Home Visits Neonatal Mortality Trial
Introduction: Just under four million infants die each year before reaching one month of age; neonatal deaths now account for 38% of the 10.8 million deaths among children younger than 5 years of age.
- Trial name
- Newhints (NCT00623337)
- Testing
- Home visits
- Where
- Ghana
- Volunteers
- 15,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Microbial Colonization, Microbial Superinvasion
Metagenomic Analysis of Gut Microbiome in Preterm
This is single center study. The investigators will try to know that relationships between intestinal microbiome and mortality in preterm infants and what relationships is between intestinal microbiome in preterm infants and…
- Conditions
- Microbial Colonization, Microbial Superinvasion, Microbial Substitution, Newborn Morbidity
- Trial name
- MAGMP (NCT03235635)
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Wonju Severance Christian Hospital
Perinatal Death
Evaluation of Enhanced Delivery and Newborn Kit
The evidence is required to assess the effectiveness of enhanced delivery and newborn kits as compared to standard delivery kits in the flood affected districts that can increase the utilization of services and reduce the delays…
- Trial name
- NCT05640063
- Testing
- Enhanced Delivery and Newborn kit
- Where
- Pakistan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Extracorporeal Life Support, Extracorporeal Membrane Oxygenation
Quality Improvement to Reduce Mortality or Severe Intracranial Hemorrhage in Neonatal Extracorporeal Life Support
This is a three-year pre- and post- interventional study to assess the effectiveness of collaborative quality improvement interventions on reducing mortality and severe intracranial hemorrhage (ICH) for neonates receiving…
- Conditions
- Extracorporeal Life Support, Extracorporeal Membrane Oxygenation, Quality Improvement, Intracranial Hemorrhage
- Trial name
- NCT05075486
- Testing
- Collaborative quality improvement
- Sponsor
- Children's Hospital of Fudan University
Pregnancy Complications
Operations Research to Improve Newborn Health
This study is designed to look at how operations are carried out in relation to improving the health and survival of newborn babies in India.
- Trial name
- NCT00198887
- Testing
- Operations research
- Where
- India
- Volunteers
- 59,651 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Neurodevelopment, Neonatal Mortality
Newborn Kit to Save Lives and Brains in Kenya
Each year, more than 3 million neonatal deaths occur worldwide and greater than 200 million children under the age of 5, almost all in low- and middle-income countries, are not fulfilling their developmental potential.
- Trial name
- NCT02208960
- Testing
- Neonatal Kit, Neonatal Stimulation
- Where
- Kenya
- Volunteers
- 2,294 people
- Sponsor
- The Hospital for Sick Children
Maternal Death, Maternal Morbidity
BetterBirth: A Trial of the WHO Safe Childbirth Checklist Program
The purpose of this study is to measure the impact of a checklist-based childbirth safety program (the WHO Safe Childbirth Checklist Program) on reduction of severe maternal, fetal, and newborn harm in institutional deliveries in…
- Conditions
- Maternal Death, Maternal Morbidity, Stillbirth, Neonatal Death
- Trial name
- BetterBirth (NCT02148952)
- Testing
- WHO Safe Childbirth Checklist Program
- Where
- India
- Volunteers
- 157,689 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Sepsis, Pneumonia
Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project
The purpose of this study is to determine whether an integrated EmONC package (community mobilization, training of community-based health care providers and a maternal and neonatal health pack) reduce perinatal and neonatal…
- Conditions
- Sepsis, Pneumonia, Omphalitis, Birth Asphyxia
- Trial name
- EmONC (NCT01751945)
- Testing
- EmONC package
- Where
- Pakistan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Morbidity;Newborn, Morality
Improving Outcome of Very Preterm Infants Using Collaborative Quality Improvement
A multicenter interventional study using evidence-based collaborative quality improvement to reduce mortality and major morbidities of very preterm infants in six neonatal centers in Shanghai
- Trial name
- NCT04531839
- Testing
- Evidence-based collaborative quality improvement
- Where
- 6 sites in China
- Sponsor
- Children's Hospital of Fudan University
Eisenmenger Syndrome
Eisenmenger Syndrome in the Nordic Countries
This is a historical cohort study with retrospective collection of data comprising all Nordic patient's diagnosed with Eisenmengers syndrome in the period 1977 through 2011.
- Trial name
- NCT01976533
- Where
- 4 sites in Denmark, Finland and 2 more
- Volunteers
- 714 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Perinatal Mortality, Cause of Neonatal Death
Verbal Autopsy to Assess Early Neonatal Death and Stillbirth
The NICHD Global Network (GN) for Women's and Children's Health Research, a multi-site, international research network, provides a unique infrastructure to implement an expanded perinatal verbal autopsy study using the FIRST…
- Conditions
- Perinatal Mortality, Cause of Neonatal Death, Cause of Stilbirth
- Trial name
- VA (NCT00640055)
- Testing
- Coordinator, Physician-assigned cause of death
- Where
- 4 sites in Guatemala, Pakistan and 2 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health