Clinical trials: Neonatal Mortality
Screening, Aortic Aneurysm and Dissection
A Study to Evaluate the Feasibility of Screening Relatives of Patients Affected by Non-Syndromic Thoracic Aortic Diseases
The primary hypothesis is that a tailored programme of genetic and imaging screening of first- and second-degree relatives of patients affected by non-syndromic forms of thoracic aortic diseases will identify individuals at risk…
- Conditions
- Screening, Aortic Aneurysm and Dissection, Genetic Disease
- Trial name
- ReST (NCT03861741)
- Testing
- WES, MRI, TTE
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Premature Birth
Assessment of the Impact of the Return Home of Premature Newborns Less Than 2 Kilos Morbidity/Mortality
The aim of this study is to evaluate the impact of discharge from hospital with a weight of less than 2 kilos. To do this, the investigator will look at the short-term and long-term outcome of newborns weighing less than 2 kilos…
- Trial name
- Petit-Poids (NCT06224764)
- Testing
- Mother and Father questionnaires
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hôpital NOVO
Prematurity, Neonatal Encephalopathy
Evaluating the NeoTree in Malawi and Zimbabwe
Neonatal mortality remains unacceptably high. Globally, the majority of mothers now deliver in health facilities in low resource settings where quality of newborn care is poor.
- Conditions
- Prematurity, Neonatal Encephalopathy, Neonatal Sepsis, Neonatal Death
- Trial name
- NCT05127070
- Testing
- Neotree
- Where
- 5 sites in Malawi, Zimbabwe
- Volunteers
- 19,000 people
- Sponsor
- University College, London
Bronchopulmonary Dysplasia (BPD), Mortality Prediction
Chloride Imbalance in Preterm Infants
In adults and children low or high blood chloride levels are linked to the risk of death. The aim of this observational study is to determine whether there is a relationship between low or high blood chloride levels and the risk…
- Conditions
- Bronchopulmonary Dysplasia (BPD), Mortality Prediction, Chloride Disorder
- Trial name
- NCT06940856
- Testing
- Incomplete response, Complete response, Bad response
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Mortality
Impact of the Integrated Management of Neonatal and Childhood Illness Strategy on Neonatal and Infant Mortality
This study is a cluster-randomized trial being conducted in the state of Haryana in North India. Eighteen geographical areas served by Primary Health Centres (PHCs) have been randomized to intervention or comparison areas.
- Trial name
- IMNCI-India (NCT00474981)
- Testing
- IMNCI
- Where
- India
- Volunteers
- 66,600 people, healthy volunteers welcome
- Sponsor
- Society for Applied Studies
Perinatal Morbidity, Morbidity;Perinatal
Multicentric Retrospective Study of Perinatal Mortality
Background: Perinatal mortality ranges mortality from 22 gestational weeks up to the first 7 days of life and extended mortality goes up to 28 days of life.
- Conditions
- Perinatal Morbidity, Morbidity;Perinatal, Stillbirth, ICD
- Trial name
- PM-PHD-NTM (NCT05491772)
- Where
- Spain
- Volunteers
- 468 people
- Sponsor
- Corporacion Parc Tauli
Premature Birth, Perinatal Mortality
Assessing the Impact of Smoke-free Legislation on Perinatal Health in the Netherlands
The purpose of this study is to investigate whether there has been a change in perinatal outcomes following the phased smoking ban introduction (January 2004 for workplaces; July 2008 for bars and restaurants) workplaces in the…
- Conditions
- Premature Birth, Perinatal Mortality, Infant, Low Birth Weight, Stillbirth
- Trial name
- NCT02189265
- Testing
- Smoke-free legislation
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 2,069,695 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Newborns
Intervention of Psychological and Ethical Professionals of Human Science in Obstetrical Morbidity and Mortality Conferences (OPERA)
This cluster-randomised controlled trial will test the hypothesis that a multifaceted program with psychological intervention in morbidity mortality conferences (MMC) improve care quality and reduce the rate of morbidity…
- Trial name
- OPERA (NCT02584166)
- Testing
- multifaceted program
- Volunteers
- 4,929 people
- Sponsor
- Hospices Civils de Lyon
Morbidity;Newborn
Antenatal Steroids Effect on Mortality and Respiratory Outcomes in Preterm Infants
The aim is to evaluate the impact of a complete course of antenatal steroids treatment on mortality and main morbidities in a current population of preterm infants.
- Trial name
- NCT04214795
- Testing
- Observational study. Postnatal variables are recorded
- Where
- Spain
- Volunteers
- 710 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Vitamin A Deficiency
Newborn Vitamin A (VA) Supplementation Pilot Project, Pakistan
Vitamin A is an essential micronutrient for the normal functioning of the visual system, growth and development, immunity and reproduction. Its deficiency causes anemia, growth retardation and xerophthalmia.
- Trial name
- VA (NCT00674089)
- Testing
- Vitamin A
- Where
- Pakistan
- Volunteers
- 7,400 people, healthy volunteers welcome
- Sponsor
- Aga Khan University