Clinical trials: Neoplasia Prostate
Patients Scheduled for Prostate Biopsy Because of Increased Serum PSA and/or Abnormal Digital Rectal Examination
Medical Economics of Urinary PCA3 Test for Prostate Cancer Diagnosis
The ultrasound-guided biopsies of the prostate is the validated technique for the diagnosis of prostate cancer, the first human cancer and second leading cause of cancer death.
- Trial name
- NCT01632930
- Testing
- urinary PCA3 test using Progensa® PCA3 assay kit (Gen-Probe)
- Where
- 10 sites in France
- Volunteers
- 962 people
- Sponsor
- Hospices Civils de Lyon
Prostate Cancer
Family History in Prostate Cancer Patients in Taiwan
To investigate the prevalence of family history in prostate cancer patients in Taiwan and evaluate the association of variation of diseases and family history
- Trial name
- NCT00155025
- Where
- Taiwan
- Volunteers
- 1,500 people
- Sponsor
- National Taiwan University Hospital
Prostate Cancer
Postoperative Pain Control for Prostatectomy
The researchers propose to investigate a relatively new anesthetic procedure, in order to maximize patient comfort and minimize the use of narcotics after a radical prostatectomy.
- Trial name
- TAP (NCT00913068)
- Testing
- Transverse Abdominal Plan (TAP), standard post op pain control
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Nova Scotia Health Authority
Prostate Cancer
Cabozantinib and Androgen Ablation in Patients With Androgen-Dependent Metastatic Prostate Cancer
The goal of this clinical research study is learn if adding cabozantinib (also known as XL184) to hormonal therapy can help to control prostate cancer. The safety of this drug will also be studied.
- Trial name
- NCT01630590
- Testing
- Cabozantinib, Androgen Ablation Therapy
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer (Adenocarcinoma)
Predictive Factors for 10-year Biochemical Recurrence and Urinary Continence Following Robot-assisted Radical Prostatectomy for Prostate Cancer
The aim of the present project is to evaluate long-term oncological and functional treatment outcomes, as well as patient satisfaction, ten years after radical prostatectomy in patients initially enrolled in CPRRP study.
- Trial name
- NCT07439913
- Testing
- Radical prostatectomy
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica
Obesity, Prostate Cancer
Effect of Weight Loss on Prostate Cancer Pathology
The purpose of this study is to determine if weight loss prior to radical prostatectomy effects chemical substances in the blood stream and prostate tissue that may affect prostate cancer development and progression.
- Trial name
- NCT00475982
- Testing
- Weight Loss, No Weight Loss Group
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Prostate Cancer
Pathological Positivity Rate in Prostate Cancer Patients with PI-RADS 4 and First Negative Biopsy
The purpose of this prospective, single-center, single-arm trial was to evaluate the pathologic type of re-treatment based on a clear PI-RADS score of ≥4 with a first negative prostate biopsy, belonging to the high-risk group of…
- Trial name
- NCT06677775
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Anhui Provincial Hospital
Metastatic Cancer, Prostate Cancer
Docetaxel and Imatinib Mesylate in Treating Patients With Androgen-Independent Prostate Cancer and Bone Metastases That Progressed on the Docetaxel and Placebo Group of MDA-ID-030008
RATIONALE: Drugs used in chemotherapy such as docetaxel work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00084825
- Testing
- Docetaxel, Imatinib mesylate
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Cancer, Breast Cancer
Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis
The aim of this observational study is to comprehensively analyze the metabolites in plasma samples from multi-cancer patients using advanced mass spectrometry detection technology, in conjunction with metabolomics approaches.
- Conditions
- Lung Cancer, Breast Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT06363123
- Where
- 4 sites in China
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Prostate Cancer
Coping in African American Prostate Cancer Survivors
This study will test the effectiveness of an 8-week group intervention for African American men who have been treated for prostate cancer.
- Trial name
- CAAPS (NCT00589966)
- Testing
- Coping Skills Training, Prostate Cancer Education
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Duke University
Prostatic Neoplasms, Lymphatic Metastasis
Prospective Validation of Pathology-based Artificial Intelligence Diagnostic Model for Lymph Node Metastasis in Prostate Cancer
The goal of this diagnostic test is to prospectively test the performance of pre-developed artificial intelligence (AI) diagnostic model for detecting pathological lymph node metastasis (LNM) of prostate cancer.
- Trial name
- NCT06253065
- Testing
- Artificial intelligence (AI)-based diagnostic model (developed)
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Prostatic Cancer
Cleaning the Biopsy Needle in TRUS Bx
Prostate cancer(PCa) is the second most common cancer diagnosed in men. Clinical suspicion of PCa is mentioned in patients with digital rectal examination findings and elevated serum PSA.
- Trial name
- NCT06836271
- Testing
- Isopropyl Alcohol, Povidine-iodine, formaldehit
- Volunteers
- 200 people
- Sponsor
- Hitit University
Prostate Cancer
Evaluation of a Blood Biomarker to Try and Distinguish Between the Presence or Absence of Aggressive Prostate Cancer
A Laboratory Study to Evaluate Urine and Blood Biomarkers That Can Distinguish Between the Presence or Absence of Aggressive Prostate Cancer
- Trial name
- NCT03256630
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Genomic Health®, Inc.
Castration-resistant Prostate Cancer
Study to Gather Information on the Safety and How Radium-223 Dichloride, an Alpha Particle-emitting Radioactive Agent, Works Under Routine Clinical Practice in Taiwan in Patients With Castration-resistant Prostate Cancer (CRPC) Which Has Spread to the Bone
In this observational study researchers want to gather more information about safety and survival in patients suffering from castration-resistant prostate cancer (CRPC) which has spread to the bone and were treated with…
- Trial name
- RAPIT (NCT04232761)
- Testing
- Radium-223 dichloride (Xofigo, BAY88-8223)
- Where
- Taiwan
- Volunteers
- 194 people
- Sponsor
- Bayer
Prostate Cancer, Prostate Cancer Stage
Comparison of Multiparametric Prostate MRI and Ga-68 PSMA PET Imaging in Prostate Cancer Staging
In this study, it is aimed to compare the lesion location, lesion size, local and distant metastases detection rates of Ga68 PSMA PET and Multiparametric Prostate MR imaging tests used in staging in patients diagnosed with…
- Trial name
- NCT05427864
- Testing
- Multiparametric Prostate MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Gulhane Training and Research Hospital
Prostate Cancer
Prostate Cancer Diagnosis Through NMR Spectroscopy of Semen and Prostatic Secretions
To develop the hypothesis that quantitative NMR spectroscopy of human semen can be used to diagnose prostate cancer.
- Trial name
- NCT00250757
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- New Mexico Cancer Research Alliance
Prostate Cancer
Rectal Spacer for Prostate Cancer Radiation Image Guidance
The purpose of the study is to determine if a radiopaque hydrogel rectal spacer, SpaceOAR Vue®, can be used in place of fiducial markers when aligning patients for radiotherapy.
- Trial name
- NCT05650021
- Testing
- SpaceOAR Vue
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Milton S. Hershey Medical Center
Prostatic Neoplasms
Impact of Adjuvant Statin Therapy in Patients Who Underwent Radical Prostatectomy for Locally Advanced Prostate Cancer
Biochemical recurrence develops in approximately 30-40% of men with locally advanced prostate cancer who undergo radical prostatectomy.
- Trial name
- NCT01759836
- Testing
- Atorvastatin 20mg
- Where
- South Korea
- Volunteers
- 364 people
- Sponsor
- Asan Medical Center
Prostate Cancer
Biological Therapy in Treating Patients With Prostate Cancer
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop tumor cells from growing. Treating a person's T cells in the laboratory and then reinfusing them may cause a stronger immune response and…
- Trial name
- NCT00039299
- Testing
- therapeutic autologous lymphocytes
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment
Group Therapy Compared With Educational Materials in Patients With Prostate Cancer
RATIONALE: Developing coping strategies may help improve the quality of life of patients with prostate cancer. PURPOSE: This randomized clinical trial is comparing the effect of group therapy with written educational materials on…
- Trial name
- NCT00002848
- Testing
- psychosocial assessment and care, quality-of-life assessment
- Where
- 7 sites in United States
- Volunteers
- 480 people
- Sponsor
- Gary Morrow