Clinical trials: Nerve Block
Inferior Alveolar Nerve Block in Children
Clinical Success of 12 mm Needle IANB in Children
This prospective single-arm pilot study will evaluate the clinical success of an inferior alveolar nerve block performed using a 12 mm 30-gauge extra-short dental needle in children aged 4 to 12 years.
- Trial name
- NCT07791082
- Testing
- 12 mm 30-Gauge Extra-Short Dental Needle
- Where
- Egypt
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Complication Following Peripheral Nerve Block
Nalbuphine as Adjuvant During Bilateral Suprazygomatic Maxillary Nerve Block for Pediatric Cleft Palate Repair
The aim of this study is to evaluate the efficacy of adding nalbuphine to bupivacaine via suprazygomatic nerve block for postoperative pain control and emergence agitation management in pediatrics aged from to 1 to 7 years who…
- Trial name
- NCT06100315
- Testing
- Nalbuphine, Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Nerve Block/Methods
Comparing Suprascapular Nerve Block and Interscalene Block for Post-thoracotomy Pain in Pediatric Patients.
The goal of this clinical trial is to determine which regional block provides superior analgesia in pediatric patients undergoing thoracic surgery.
- Trial name
- NCT07796399
- Testing
- Interscalene brachial plexus block, anterior Supraclavicular nerve block, Thoracic Epidural Analgesia (TEA) only
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Pericapsular Nerve Group Block
Combined Pericapsular Nerve Group Block and Lateral Femoral Cutaneous Nerve Block for Pediatric Hip Surgeries
combined pericapsular nerve group PENG block and lateral femoral cutaneous nerve block may be effective in reducing post-operative pain after open hip surgery in children.
- Trial name
- NCT06417268
- Testing
- Caudal epidural analgesia, Ultrasound-guided Combined Pericapsular Nerve Group Block, Ultrasound-guided Lateral Femoral Cutaneous Nerve Block
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Kasr El Aini Hospital
Hypospadias, Pudendal Nerve Block
Ultrasound-Guided Pudendal vs Dorsal Penile Nerve Block for Pediatric Hypospadias Surgery
The goal of this clinical trial is to compare the effectiveness and safety of two regional anesthesia techniques, ultrasound-guided pudendal nerve block and dorsal penile nerve block, for postoperative pain management in children…
- Conditions
- Hypospadias, Pudendal Nerve Block, Penile Nerve Block, Postoperative Pain
- Trial name
- NCT07575204
- Testing
- Ultrasound-Guided Pudendal Nerve Block, Ultrasound-Guided Dorsal Penile Nerve Block
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Quadratus Lumborum Nerve Block, Erector Spinae Block
Comparison of ESP and QL Blocks for Postoperative Pain in Pediatric Appendectomy (ESP-QLB)
This prospective randomized controlled clinical trial aims to compare the analgesic effectiveness of the Erector Spinae Plane (ESP) block and the Quadratus Lumborum (QL) block in pediatric patients undergoing appendectomy.
- Trial name
- ESP-QLB (NCT07301528)
- Testing
- Quadratus Lumborum Block (QLB), Erector Spinae Plane Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Zeycan Kahya
Regional Anesthesia Success, Pain Monitor During Anesthesia
Comparison of Caudal and Quadratus Lumborum Blocks With Pain Monitoring in Children
Study Type: Prospective, Randomized, Observational Clinical Study Primary Purpose: The primary objective of this study is to compare the analgesic efficacy of caudal block (CB) and quadratus lumborum block (QLB) in children…
- Conditions
- Regional Anesthesia Success, Pain Monitor During Anesthesia, Quadratus Lumborum Nerve Block, Caudal Block for Postoperative Analgesia
- Trial name
- NCT07398573
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara Etlik City Hospital
Chronic Migraine Headache, Radiofrequency Ablation
The Effect of Interventional Procedures on Serum CGRP and PACAP-38 Levels in Chronic Migraine
The study included 100 patients diagnosed with chronic migraine (CM) who received a diagnosis from the headache clinics of the Neurology Department of Adnan Menderes University Hospitals between May 2025 and May 2026.
- Conditions
- Chronic Migraine Headache, Radiofrequency Ablation, Greater Occipital Nerve Block, Calcitonin Gene-related Peptide
- Trial name
- NCT07395908
- Testing
- Greater occipital nerve Pulse radiofrequency, Greater occipital nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Caries, Dental, Local Anesthesia
Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients
This study compares the effects of traditional behavior management techniques and AI-assisted child-friendly communication on dental anxiety, physiological stress, and pain perception during local anesthesia in healthy children…
- Conditions
- Caries, Dental, Local Anesthesia, Inferior Alveolar Nerve Block, Dental Anxiety
- Trial name
- NCT07133919
- Testing
- AI-Assisted Child-Friendly Communication, Traditional Behavior Management Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Nerve Block
Opioid-Free Pain Management After NUSS Surgery in Adolescents
The investigators applied ultrasound-guided bilateral transverse thoracic fascia block combined with intercostal nerve block-a previously unreported analgesic approach for post-thoracic surgery-to NUSS patients.
- Trial name
- NCT07288424
- Testing
- Nerve block
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Qin Zhang
Laparoscopic Abdominal Surgeries, Erector Spinae Plane Block
Erector Spinae Plane Block Versus Modified Thoracoabdominal Nerve Block for Analgesia in Pediatric Laparoscopic Abdominal Surgeries
Laparoscopic abdominal surgeries are frequently performed in pediatric patients and are often associated with significant postoperative pain, which, if inadequately managed, may delay recovery and increase the risk of chronic…
- Conditions
- Laparoscopic Abdominal Surgeries, Erector Spinae Plane Block, Modified Thoracoabdominal Nerve Block (M-TAPA)
- Trial name
- NCT07240064
- Testing
- Erector Spinae Plane Block, Modified thoracoabdominal plane block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Nerve Blocks, Medical Education, Simulation, Crisis Resource Management
Ultrasound-guided Nerve Block Training Model and Evaluation Method
The aim of this study is to assess emergency medicine physician knowledge and technical skill in performance of ultrasound-guided serratus anterior nerve block in a low-fidelity simulation model workshop and to determine the…
- Conditions
- Nerve Blocks, Medical Education, Simulation, Crisis Resource Management, Medical Education in Emergency Ultrasound
- Trial name
- NCT06219005
- Testing
- ultrasound education and simulation workshop
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Duke University
Nerve Block, Hip Fracture Surgeries
Self-Guided Immersive Virtual Reality Versus Mannequin-based Simulators to Teach the Ultrasound-Guided Supra-Inguinal Fascia Iliaca Block
This research project aims to see if using immersive virtual reality (iVR) is as good as using traditional mannequins to teach medical staff how to perform a specific nerve block called an ultrasound-guided supra-inguinal fascia…
- Trial name
- NCT07035015
- Testing
- VR UGRA, Mannequin-based simulation
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- The Ottawa Hospital
Ultrasound, Pectoral Nerve Block
Ultrasound Guided Bilateral Pectoral Nerve Block Versus Bilateral Transverse Thoracic Plane Block In Pediatric Patients Undergoing Corrective Cardiac Surgeries Requiring Cardiopulmonary Bypass Via Median Sternotomy
This randomized, double-blinded, study aims to compare the efficacy of intraoperative and postoperative pain control while using bilateral ultrasound guided the pectoral nerves (PECS) versus transversus thoracic muscle plane…
- Conditions
- Ultrasound, Pectoral Nerve Block, Transverse Thoracic Plane Block, Pediatric Patients
- Trial name
- NCT06984276
- Testing
- Control, Pectoral nerves (PECS), Transversus thoracic muscle plane block (TTPB)
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Cairo University
Appendectomy, Laparoscopic, Pediatric Anesthesia
Rectus Sheath Block and Local Wound Infiltration in Pediatric Laparoscopic Appendectomies
Laparoscopic appendectomy surgeries are among the most commonly performed procedures in childhood. However, they are associated with moderate to severe postoperative pain.
- Conditions
- Appendectomy, Laparoscopic, Pediatric Anesthesia, Nerve Block/Methods, Regional Anesthesia
- Trial name
- NCT06913205
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people
- Sponsor
- Bursa City Hospital
Peripheral Nerve Block, Post Operative Analgesia
Transversus Abdominis Plane Lock Versus Quadratus Lumborum Block in Children
Although abdominal wall surgeries are also as routinely performed on pediatric patients, postoperative pain in children has remained under-researched compared to adults.
- Conditions
- Peripheral Nerve Block, Post Operative Analgesia, Ultrasound-guided Regional Anesthesia
- Trial name
- NCT06861556
- Testing
- Ultrasound guided Transversus Abdominis Plane block with 0.2ml/kg bupivacaine 0.25%, Ultrasound-guided Quadratus Lumborum block with 0.2ml/kg bupivacaine 0.25%
- Where
- Tunisia
- Volunteers
- 90 people
- Sponsor
- Tunis University
fMRI Research, Transcranial Magnetic Stimilation
The Relationships Between Neural Correlates of Effort Perception and Physical Activity Engagement
Objectives and research hypothesis Physical inactivity is a major health concern that has been linked to a variety of chronic diseases, including obesity, diabetes, cancer, cardiovascular diseases, and mental disorders.
- Conditions
- fMRI Research, Transcranial Magnetic Stimilation, EEG Brain Oscillations, Motor Task
- Trial name
- EffortLESS (NCT06691490)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Perfusion Index, Plethysmography
Evaluation of Caudal Block and Ilioinguinal-ilioohypogastric Nerve Block Efficacy with Perfusion Index (PI)
The study is a prospective, randomised, controlled double-blind clinical trial. The primary aim was to evaluate the efficacy of caudal block and ilioinguinal-iliohypogastric nerve block with PI and PVI in pediatric inguinal…
- Conditions
- Perfusion Index, Plethysmography, Anesthesia, Caudal, Nerve Block
- Trial name
- NCT06203743
- Testing
- caudal block group, ilioinguinal-iliohypogastric nerve block group
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Computer-controlled Intraligamentary Anaesthesia, Inferior Alveolar Nerve Block
Comparison of the Computer Controlled and Conventional Local Anesthesia Techniques in Primary Molar Extraction in Children Aged 5 to 9 Years Old
The goal of this clinical trial is to assess pain perception, child stress level and compare the effectiveness between periodontal ligament anesthesia using Computer-controlled Local Anesthetic delivery system and the…
- Conditions
- Computer-controlled Intraligamentary Anaesthesia, Inferior Alveolar Nerve Block, Pain Perception, Anesthesia Effectiveness
- Trial name
- RCT (NCT06669039)
- Testing
- Computer-controlled Local Anesthetic delivery system, Inferior Alveolar Nerve Block
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Optic Nerve Sheath Diameter, Caudal Block
Effect of Caudal Block Injection Rate on Optic Nerve Sheath Diameter in Pediatric Surgeries
Our prospective observational study will include patients between the ages of 1-7 years, ASA 1-2, who will undergo elective surgery under general anesthesia, whose consent was obtained by their parents for the procedure to be…
- Trial name
- NCT06187714
- Testing
- caudal block rate
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization