Clinical trials: Neural Responses
Depression
Neural Alteration Response to Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Depressed Patients
Electrical vagus nerve stimulation (VNS) was approved by FDA for treatment of chronic recurrent depression in 2005. Recently, non-invasive, transcutaneous auricular vagus nerve stimulation （taVNS） has already been used for…
- Trial name
- NCT03592446
- Testing
- Transcutaneous electrical vagus nerve stimulation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xidian University
Obsessive-Compulsive Disorder (OCD)
Neural Predictors and Neural Changes Associated With Cognitive Behavior Therapy for Obssesive Compulsive Disorder
The goals of the project are 1) to understand what are the neural mechanisms involved in the psychological treatment of obsessive-compulsive disorder (OCD) in children/adolescents and adults, 2) to assess potential differences in…
- Trial name
- NCT04042038
- Testing
- Cognitive-behavior therapy (psychological treatment)
- Where
- 3 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut d'Investigació Biomèdica de Bellvitge
Cannabis, Cannabis Intoxication
Do Adolescents and Adults Differ in Their Acute Response to Cannabis?
The acute effects of cannabis may differ between adolescents and adults. Furthermore, these effects may be tempered by the presence of cannabidiol.
- Conditions
- Cannabis, Cannabis Intoxication, Cannabis Use, Cannabis Dependence
- Trial name
- CannTeenA (NCT04851392)
- Testing
- Cannabis with delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), Cannabis with THC without CBD
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University College, London
Autism Spectrum Disorder
Behavioral and Neural Response to Memantine in Adolescents With Autism Spectrum Disorder
This study is a 12-week, randomized-controlled trial of memantine hydrochloride (Namenda) for the treatment of social impairment in adolescents with autism spectrum disorder (ASD).
- Trial name
- NCT01972074
- Testing
- Memantine
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pediatric Obesity
Neural Mechanisms Underlying Children's Responses to Food Portion Size and Energy Density
Increased portion sizes of foods high in energy density (calories per gram of food) have been implicated in the obesity epidemic.
- Trial name
- NCT02759523
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Penn State University
Exercise Condition (EX), Control Session (CON)
Exercise and Neural Response to Food Cues in Children
Physical exercise has been shown to significantly reduce subsequent energy intake in obese adolescents but not in lean, without altering their appetite feelings.
- Trial name
- NCT02100878
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Université Blaise Pascal, Clermont-Ferrand
Cochlear Function Disorder
Correlation Between NRT and Radiological Measurements in Detection of Position of the Electrode Inside the Cochlea.
The study will be conducted as Prospective study including 50 patients (aged <6years ) at Otorhinolaryngology department, Assuit University Hospital (aged <6years ) who will undergo cochlear implantation.
- Trial name
- NCT03306108
- Testing
- NRT
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy
Effects of Oxytocin Dose Frequency on Behavioral and Neural Responses
The main aim of the study is to examine effects of different dose frequencies of repeated oxytocin administration on neural and behavioral markers of oxytocin in healthy male subjects.
- Trial name
- NCT03610919
- Testing
- Nasal Sprays
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Electromechanical Dissociation
Electromyographic Responses by Static Stretching and Neural Mobilization
The objective of this experimental study was to compare the electromyographic responses of sedentary youth with and without the administration of static stretching and neural mobilization.
- Trial name
- NCT01379105
- Testing
- neural mobilization, Static Stretching
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Euro-American Network of Human Kinetics
Depression, Parent-Child Relations
Parent Encouragement And Coaching of Happiness in Youth
The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response to reward. The main questions it aims to answer are: Aim 1.
- Trial name
- PEACHY (NCT06725160)
- Testing
- Parent Coaching, Active Control
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Eating Disorders
Comparing Neural Responses to Food Images in EDNOS Patients and Healthy Controls Using fMRI
Currently, there is not a robust, testable neural model available that sufficiently explains the development and maintenance of anorexia nervosa (AN) a severe, often fatal, adolescent-onset eating disorder.
- Trial name
- ANfMRI (NCT01882023)
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Cochlear Hearing Loss
Changes in the Threshold of Electrically Evoked Compound Action Potential in Children Following Cochlear Implantation
After cochlear implantation, cochlear nerve is stimulated by giving a current over the electrodes placed in the cochlea and the current is measured by electrically evoked Compound Action Potential (ECAP).This ECAP is measured…
- Trial name
- NCT03500718
- Testing
- Cochlear implant
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Alcohol Approach/Avoidance Task, Sham Approach/Avoidance Task
Marijuana Approach Bias Retraining and Neural Response in Youth
This study aims to determine if a marijuana (MJ) Approach Avoidance Task (AAT) intervention reduces cannabis use compared to a control condition containing no active components of AAT.
- Trial name
- MJ-AAT (NCT02723149)
- Testing
- Marijuana Approach Avoidance Training
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina