Clinical trials: Neurodevelopmental Disability
Reading Disability, Dyslexia
Eye Movements and Reading Disabilities
The mechanism of the eye movement anomalies seen in dyslexic patients is not well defined. Some optometrists use observational eye movement tests as screening devices for dyslexia and advocate eye movement therapy as a treatment…
- Trial name
- EOMRD (NCT01860027)
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Brain Disorders, Aicardi Syndrome
Brain Development Research Program
Dr. Elliott Sherr and his collaborators at University of California, San Francisco (UCSF) are studying the genetic causes of disorders of cognition and epilepsy, in particular disorders of brain development that affect the corpus…
- Trial name
- NCT00305305
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- University of California, San Francisco
Klinefelter Syndrome, Trisomy X
The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy
This study is designed to research the natural history of neurodevelopment, health and early hormonal function in infants with XXY/Klinefelter syndrome, XYY, XXX and other sex chromosome variations in an effort to identify early…
- Conditions
- Klinefelter Syndrome, Trisomy X, XYY Syndrome, XXXY and XXXXY Syndrome
- Trial name
- NCT03396562
- Testing
- Assessments of Development and Growth
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Apnea of Prematurity
Caffeine for Apnea of Prematurity (CAP)
At least 5 of every 1000 live-born babies are very premature and weigh only 500 to 1250 grams at birth. Approximately 30-40% of these high-risk infants either die or survive with lasting disabilities.
- Trial name
- NCT00182312
- Testing
- Caffeine citrate injection
- Where
- 34 sites in United States, Australia and 7 more
- Volunteers
- 2,000 people
- Sponsor
- McMaster University
Encephalopathy, Birth Defect
Clinical Utility of Pediatric Whole Exome Sequencing
The investigator aims to examine the clinical utility of WES, including assessment of a variety of clinical outcomes in undiagnosed pediatric cases.
- Conditions
- Encephalopathy, Birth Defect, Intellectual Disability, Multiple Congenital Anomaly
- Trial name
- NCT03525431
- Testing
- Whole Exome Sequencing
- Where
- 4 sites in United States
- Volunteers
- 529 people
- Sponsor
- University of California, San Francisco
Velocardiofacial Syndrome
Computerized Cognitive Skills Training for Adolescents With Velocardiofacial Syndrome
This study will test a computer-based treatment for youth with the genetic disorder velocardiofacial syndrome (VCFS) to help them improve skills in memory, attention, and executive functioning.
- Trial name
- NCT00917189
- Testing
- Challenging Our Minds Program
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- State University of New York - Upstate Medical University
Attention-deficit Hyperactivity Disorder
A Study to Examine the Progression of Attention-Deficit Hyperactivity Disorder (ADHD) Drug Treatment and to Analyze Associated Factors
The purpose of this observational study is to explore the efficacy of methylphenidate hydrochloride in children and adolescents diagnosed with attention-deficit hyperactivity disorder (ADHD) by Kiddie-scheduled for affective…
- Trial name
- NCT01624649
- Testing
- Methylphenidate hydrochloride, Atomoxetine
- Where
- 9 sites in South Korea
- Volunteers
- 289 people
- Sponsor
- Janssen Korea, Ltd., Korea
Congenital Anomalies, Development Delay
Result Of Karyotyping in Pediatric Patients With Congenital Anomalies and Developmental Delay
The goal of this observational cross-sectional study is to study the results of karyotyping analysis for children presented with congenital anomalies and developmental delay aged 1 month to 12 years, the need for further genetic…
- Trial name
- NCT07167017
- Volunteers
- 75 people
- Sponsor
- Assiut University
Developmental Delay
Measuring the Feasibility and Preliminary Efficacy of Therapeutic Playgroups in Early Intervention
Play builds social-emotional skills. Therapeutic playgroups facilitate parent-child interaction these and provide opportunities for parents to engage with their children and other adults and learn more about development.
- Trial name
- NCT03062371
- Testing
- Playgroup
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Florida Gulf Coast University
Developmental Dyslexia
V5/MT Stimulation on Reading and Reading-related Measures in Developmental Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial direct current stimulation…
- Trial name
- NCT05972200
- Testing
- Active HD-tDCS over V5/MT, Active HD-tDCS over V1
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Child Development Disorders, Specific, Developmental Communication Disorders
Improvised Music to Enhance Intensive Interaction Version 1
The project will investigate the effectiveness of a specialised musical-clinical approach used as an adjunct to an established non-musical intervention in the enhancement of interpersonal interaction.
- Trial name
- NCT03188016
- Testing
- Intensive Interaction with Music, Standard Intensive Interaction
- Where
- United Kingdom
- Sponsor
- Beacon Hill Academy
Mental Retardation, Autism Spectrum Disorder
A Cross-sectional Study to Evaluate Speech and Language Development in Chinese Children Aged 2-6 Years
The purpose of this study is to establish a new Chinese children's speech and language norm by obtaining the latest data of speech and language development of children aged 2 ~ 6 from different regions in China.
- Conditions
- Mental Retardation, Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT05442229
- Testing
- establish a new Chinese children's speech and language norm
- Volunteers
- 5,744 people
- Sponsor
- Tongji Hospital
Autism Spectrum Disorder, Intellectual Disability
TMS for the Investigation of Brain Plasticity in Autism Spectrum Disorders
The main purpose is to study brain plasticity (the changes that occur in the brain through experience) in individuals with autism spectrum disorder (ASD).
- Trial name
- NCT02836405
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Premature, Developmental Disability
Explorer Babies Early Intervention Program
Premature babies have a high risk of adverse developmental outcomes. Early intervention approaches are applied to reduce these adverse outcomes or support of developmental delay.
- Conditions
- Premature, Developmental Disability, Cerebral Palsy, Motor Disorders
- Trial name
- NCT04203589
- Testing
- The Explorer Baby Early Intervention Program, Neurodevelopmental Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Behavioural Problems
Effectiveness of Multisystemic Therapy for Adolescents From Families With Intellectual Disabilities
The goal of this observational study is to determine the effectiveness of a specialisation of multisystemic therapy (MST) for adolescents with severe behavioural problems from families with an intellectual disability (ID…
- Trial name
- NCT06032455
- Testing
- Multisystemic therapy, Multisystemic therapy - intellectual disabilities
- Where
- 4 sites in Netherlands
- Volunteers
- 470 people
- Sponsor
- De Viersprong
Dyslexia
Reading Problems in Children Living in Urban Areas
The first line of defense against reading disabilities is good classroom reading instruction. This study describes how characteristics of students, teachers, and instruction relate to academic achievement in inner-city…
- Trial name
- NCT00065832
- Testing
- Reading Instruction
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Intellectual Disability, Mild, Educational Problems
Therapy Program for Academic Skills in Children With Intellectual Disability
The aim of this study is to investigate the effect of a physical and occupational therapy program on academic skills in a sample of Egyptian children with intellectual disability.
- Trial name
- NCT05900830
- Testing
- play therapy, common educational methods
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Beni-Suef University
Developmental Delay
Improving Neurodevelopmental ouTcomes After Prenatal Cannabinoid in uTero Exposure
The INTACT trial is a multisite pilot feasibility study aimed at testing the effectiveness of the INTACT Intervention program in improving neurodevelopmental outcomes in infants prenatally exposed to cannabinoids.
- Trial name
- INTACT (NCT06423664)
- Testing
- Play and Learn Strategies (PALS) Program
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IDeA States Pediatric Clinical Trials Network
Developmental Disability, Developmental Dyslexia
Postural Control, Grip Strength and Body Posture in Children With Intellectual Disability and Dyslexia
This study investigates physical changes in children with Dyslexia and Intellectual Disability. Participants divided into three groups and Body Posture, Postural Control and Hand Grip Strengths was evaluated.
- Conditions
- Developmental Disability, Developmental Dyslexia, Intellectual Disability
- Trial name
- NCT04250701
- Testing
- Body Posture Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ahmet Emir
Developmental Delay (Disorder)
Mindful Movement And GAME BASED Training In Developmental Delay
Developmental delay in children is characterized by delayed acquisition of cognitive, motor, language, and social skills and is commonly associated with conditions such as cerebral palsy, autism spectrum disorder, and genetic…
- Trial name
- MINDGAME (NCT07575165)
- Testing
- Mindful movement, Game based training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University