Clinical trials: Neurodevelopmental Disorder
Bronchopulmonary Dysplasia
Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia
The purpose of this study is to determine if late doses of Infasurf surfactant given when patients are receiving inhaled nitric oxide will interact to improve surfactant function and increase survival without BPD in treated…
- Trial name
- TOLSURF (NCT01022580)
- Testing
- Infasurf surfactant (ONY, Inc.)
- Where
- 21 sites in United States
- Volunteers
- 511 people
- Sponsor
- Roberta Ballard
Developmental Disabilities
The Experiences of Parents Learning Physiotherapy Techniques for Their Child
The experiences of learning from paediatric physiotherapists were explored through unstructured interviews applying Colazzi's method to interpret the data.
- Trial name
- NCT02090946
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Western Sussex Hospitals NHS Trust
Autism Spectrum Disorder
Intelligence Quotient Assessment in Children With Autistic Spectrum Disorders.
The aim of this study is to assess the cognitive strengths and weaknesses of children with autism and the possible effect of age and IQ on Stanford-Binet Intelligence Scale, 5th Edition.
- Trial name
- NCT04066673
- Testing
- Stanford-Binet Intelligence Scale, 5th Edition
- Volunteers
- 40 people
- Sponsor
- Assiut University
ADHD
The Effect of Physical Effort in the Decision Making Process of Preadolescents With ADHD
In the current study we will examine a specific aspect of these processes that has yet to be studied. We will test the effect that a physically effortful assignment has on the choices that a preadolescent makes using a forced…
- Trial name
- NCT01978769
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Shaare Zedek Medical Center
Tourette Syndrome, Tic Disorder, Chronic Motor or Vocal
Open-label MNS for Tourette Syndrome
A recent report (Morera Maiquez et al 2020) described reduced tic severity in people with Tourette syndrome during 1-minute epochs of median nerve stimulation (MNS) at 10 Hz.
- Trial name
- NCT05016765
- Testing
- Active, self-directed electrical stimulation of the median nerve
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Washington University School of Medicine
ADHD
Randomized, Double-blind Safety and Efficacy Study of Lisdexamfetamine Dimesylate (LDX) in Children and Adolescents Aged 6-17
The main aim of this study is to see if giving LDX to children and adolescents aged 6-17 years with ADHD decreases symptoms of ADHD.
- Trial name
- NCT00763971
- Testing
- Lisdexamfetamine Dimesylate (LDX), Methylphenidate Hydrochloride
- Where
- 49 sites in Belgium, France and 8 more
- Volunteers
- 336 people
- Sponsor
- Shire
Gastrointestinal Disorders, Autism Spectrum Disorders
Understanding Gastrointestinal Conditions in Children With Autism Spectrum Disorder (ASD)
The purpose of this research study is to help us learn if children with Autism Spectrum Disorder (ASD) have gastrointestinal (stomach and intestine) problems more frequently than children without ASD do.
- Trial name
- NCT01675414
- Testing
- evaluation visit by a pediatric gastroenterologist
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Massachusetts General Hospital
Autistic Disorder
A Controlled Study of Olanzapine in Children With Autism
This is a 12-week study which investigates the use of olanzapine to decrease disruptive behaviors sometimes associated with Autism in children, aged 3 to 12 years old.
- Trial name
- NCT00057408
- Testing
- olanzapine (Zyprexa)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- FDA Office of Orphan Products Development
Mood Disorder, Mental Disorder Diagnosed in Childhood
A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation
Severe mood dysregulation (SMD) is a very common syndrome in children. Its symptoms include very severe irritability, including persistent anger and frequent outbursts, as well as distractibility, hyperactivity, and other…
- Conditions
- Mood Disorder, Mental Disorder Diagnosed in Childhood, Attention Deficit and Disruptive Behavior Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT00794040
- Testing
- Add-on citalopram following optimized methylphenidate
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder, Autism
Mitochondrial Dysfunction in Autism Spectrum Disorder
Researchers at Arkansas Children's Hospital Research Institute are conducting a study about mitochondrial function in children. The study involves up to 5 visits to Arkansas Children's Hospital with fasting blood draws…
- Conditions
- Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
- Trial name
- Mito (NCT02000284)
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Physical Activity, Health Promotion
Move it, Move ID! Promotion of Physical Activity in Adolescents With Intellectual Disability
The aim of this study is to develop and implement an mHealth intervention focusing on the promotion of physical activity in adolescents with intellectual disability.
- Conditions
- Physical Activity, Health Promotion, Adolescents, Intellectual Disability
- Trial name
- NCT05149443
- Testing
- theory-based mHealth-intervention (app)
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Ghent
Developmental Delay Disorder, Genetic Disease
Turkish Affordances in the Home Environment for Motor Development-Infant Scale (AHEMD-IS)
Environment which children live and grown is very important for the all development stages. In Turkey there is no measurement for home environment evaluation so our aim is to investigate the Psychometric Properties of the Turkish…
- Conditions
- Developmental Delay Disorder, Genetic Disease, Metabolic Disease, Congenital Disorders
- Trial name
- NCT04556487
- Testing
- evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Autism, Autism Spectrum Disorder
Trial of Zolpidem for Sleep in Children With Autism
The purpose of this study is to examine the effect of zolpidem on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Zolpidem is a nonbenzodiazepine GABAa receptor agonist drug that acts as a hypnotic.
- Trial name
- NCT05540574
- Testing
- Zolpidem
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Stanford University
Attention Deficit Disorder With Hyperactivity
NEUROFEEDBACK on Event-Related Potential (ERP)
This project aims to assess the evolution of symptoms in ADHD children from 8 to 17 years, with various types of attention training.
- Trial name
- MyB (NCT03289793)
- Testing
- Neurofeedback training, Baseline control group
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Hospices Civils de Lyon
Tourette Syndrome, Chronic Tic Disorder
VoIP Delivered Behavior Therapy for Tourette Syndrome
The purpose of this research is to examine the preliminary efficacy, feasibility, and acceptability of Voice over Internet Protocol delivered behavior therapy for Tourette Syndrome through in a randomized waitlist-controlled…
- Trial name
- NCT02247206
- Testing
- Behavior Therapy for Tics (CBIT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Milwaukee
Acquired Brain Injury, Alexia
Treatment for Reading and Writing Deficits Following Acquired Brain Injury
Many people with acquired brain injuries have deficits in reading decoding, reading comprehension, and written expression. Alexia is a phenomenon in which a person who previously could read has trouble doing so after having…
- Conditions
- Acquired Brain Injury, Alexia, Agraphia
- Trial name
- NCT03662243
- Testing
- Multicomponent reading and writing treatment
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Quality Living, Inc.
Obesity, Genetic Disorder
Brain-Derived Neurotrophic Factor in Obesity and Brain Function
Background: Prader-Willi syndrome (PWS) and MC4R genetic mutations are two conditions that can cause problems with appetite regulation. People with PWS often have behavior and thinking problems.
- Conditions
- Obesity, Genetic Disorder, Mental Retardation, Developmental Delay
- Trial name
- NCT01517048
- Where
- 2 sites in United States, Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder
Autism Biomarker Consortium for Clinical Trials (ABC-CT): Follow-up Study
This is a multicenter longitudinal follow-up study to the main study of an a registered already (NCT# ). The Follow-up Study (T4) will assess the Main Study cohort for an additional longitudinal time point approximately 2-5 years…
- Trial name
- ABC-CT (NCT04841525)
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism Spectrum Disorders
Telehealth Coaching for Families of Children With Autism
The purpose of this study is to investigate the efficacy of a 12 week telehealth intervention for families of children with autism spectrum disorders under the age of 6 years on child participation and parent efficacy.
- Trial name
- NCT02928068
- Testing
- Occupational Performance Coaching (OPC)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Fragile X Syndrome, Fragile X Mental Retardation Syndrome
A Trial of Metformin in Individuals With Fragile X Syndrome
This study is a controlled trial of metformin in individuals with fragile X syndrome between the ages of 6 and 25 years. Participants will be randomized in a double-blind design to either drug or placebo and will attend three…
- Conditions
- Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X Linked, Genetic Diseases, X-Linked
- Trial name
- Met (NCT03479476)
- Testing
- Metformin
- Where
- 3 sites in United States, Canada
- Volunteers
- 120 people
- Sponsor
- University of California, Davis
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