Clinical trials: Neurodevelopmental Disorders
Cerebral Palsy, Hemiplegic, Sensory Processing Disorder
Sensory Processing, Postural Stability, and Selective Motor Control in Children With Hemiplegia
The goal of this observational case-control study is to examine the relationship between sensory processing abilities, postural stability, and selective motor control (SMC) in children aged 6-10 years with hemiplegic cerebral…
- Conditions
- Cerebral Palsy, Hemiplegic, Sensory Processing Disorder, Postural Balance, Motor Skills Disorders
- Trial name
- HeSPoM (NCT06989034)
- Testing
- Child Sensory Profile 2 (SP2) for Sensory processing abilities, HUMAC Balance System for Postural stability evaluation, Selective Motor Control Evaluation for the upper and lower extremities
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Autism
Improving Caregiver Engagement in Early Interventions
The goal of this study is to test the effectiveness of the FANS-EI program in supporting caregiver engagement in caregiver-mediated early interventions for young children with autism.
- Trial name
- NCT07500363
- Testing
- FANS-EI, Early Intervention
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, Davis
ADHD
Prevention of Cigarette Smoking in Attention Deficit Hyperactivity Disorder (ADHD) Youth With Concerta
This study will consist of a six-week open-label treatment period with an extended duration methylphenidate (OROS MPH) followed by subsequent monthly visits for 24 months in a large sample of youths aged 12-17 who meet Diagnostic…
- Trial name
- NCT00181714
- Testing
- methylphenidate HCl (Concerta)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Massachusetts General Hospital
Neurodevelopmental Disorders, Irritability
AP Metabolism Transcriptomics
It is known from the literature that treatment with antipsychotic drugs (AP) induces, even before changes in blood chemistry parameters, changes in gene transcription that are evident at the level of peripheral blood mononuclear…
- Trial name
- NCT06814314
- Testing
- Transcriptomic investigation
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Eugenio Medea
Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders
Study of Children at Risk for Disruptive Behavior Disorders
A conduct disorder is characterized by repetitive and persistent patterns of behavior where the basic rights of others and rules are violated.
- Conditions
- Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders, Passive-Aggressive Personality Disorder
- Trial name
- NCT00001233
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
ADHD - Attention Deficit Disorder With Hyperactivity
Medication Treatment of ADHD in Pediatric Epilepsy
This is an observational study assessing the usage of stimulant medication for ADHD in the context of pediatric epilepsy.
- Trial name
- NCT07594652
- Testing
- methylphenidate hydrochloride (Jornay PM)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
ADHD - Attention Deficit Disorder With Hyperactivity
Clinical Study of Non-invasive 40-Hz Audiovisual Stimulation Guided by Gamma EEG Monitoring for Promoting Perioperative Brain Function Recovery in Children
Exposure to general anesthesia during early brain development has emerged as an important risk factor for long-term attention-deficit/hyperactivity disorder (ADHD)-like behaviors and learning difficulties in school-aged children.
- Trial name
- NCT07719465
- Testing
- 40-Hz non-invasive synchronized audiovisual stimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Preterm, Parent-Child Relations
Sensory Optimization of the Hospital Environment
The long-term goal of this project is to improve the health and well-being of preterm infants and their parents. Although there is evidence to support positive multisensory interventions in the NICU, these interventions are often…
- Conditions
- Preterm, Parent-Child Relations, Parents, Development, Infant
- Trial name
- SOOTHE (NCT05230199)
- Testing
- SENSE multisensory program, Monitored standard of care
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- University of Southern California
ADHD, ADD
ADHD Electrophysiological Subtypes and Implications in Transcranial Direct-current Stimulation
In the present study the aim is to examine whether transcranial direct-current stimulation (tDCS) generated excitability changes and induce modifications of functional cortical architecture in Attention Deficit Hyperactivity…
- Trial name
- tdcs&adhd (NCT01649232)
- Testing
- Active tDCS
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Spanish Foundation for Neurometrics Development
Speech Sound Disorders
Ultrasound Biofeedback for Speech Sound Disorders
Children with speech sound disorders will receive speech therapy using real-time images of the tongue from ultrasound. These images will be used to cue the child to change the tongue position when producing speech sounds.
- Trial name
- NCT01905449
- Testing
- Ultrasound visual feedback
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Yale University
ADD, ADHD
Neurocognitive and Neurobiological Improvement in ADHD Children With High Protein Diet
Multicenter, Prospective, randomized, comparative and controlled study about the beneficial effects in behavior and brain connectivity of different dietary patterns in 100 children with ADHD between 7 and 12 years, followed up…
- Trial name
- BrainProtein (NCT02614599)
- Testing
- BP22042013, Low carbohydrate diet
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Spanish Foundation for Neurometrics Development
Autistic Disorder, Autism
Withdrawal Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified Previously Treated With Memantine
The purpose of this randomized withdrawal study is to evaluate the safety, tolerability, and efficacy of memantine compared with placebo in pediatric patients with autism, Asperger's Disorder, or Pervasive Developmental Disorder…
- Conditions
- Autistic Disorder, Autism, Asperger's Disorder, Asperger Syndrome
- Trial name
- NCT01592747
- Testing
- Memantine Hydrochloride (HCl)
- Where
- 94 sites in United States, Belgium and 13 more
- Volunteers
- 479 people
- Sponsor
- Forest Laboratories
Autism Spectrum Disorder, Obesity
Semaglutide in Youth With Autism Spectrum Disorder
This study is a 6-month, two-arm, RCT which will evaluate the effectiveness and safety of semaglutide in adolescents aged 12-18 years with autism spectrum disorder (ASD) and obesity.
- Trial name
- GLP1 (NCT07770152)
- Testing
- Glucagon-like peptide-1 receptor agonist：Semaglutide, Lifestyle Management (LSM) Counseling
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Selective Mutism
Evaluating an Online Adjunctive Support Following Intensive Services (OASIS) Strategy for Youth With Selective Mutism
This study sought to evaluate an innovative post-acute continuation/transition planning treatment strategy that leveraged an in-person intensive treatment followed by online, videoconferencing-based "booster" sessions for youth…
- Trial name
- NCT04291638
- Testing
- Remote Caregiver Training, Remote Intensive Group Behavioral Treatment (IGBT)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Florida International University
Tourette's Disorder, Persistent (Chronic) Motor or Vocal Tic Disorder
TicHelper: A Computerized Comprehensive Behavioral Intervention for Tics (CBIT)
Tic Disorders (including Tourette Disorder) are relatively common in school-age children and for some children can lead to significant psychosocial and physical impairment and diminished quality of life.
- Trial name
- NCT02413216
- Testing
- TicHelper, Internet Based Resources
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Utah
Refractive Error, Visual Impairment
The Baltimore Reading and Eye Disease Study
The Baltimore Reading and Eye Disease Study (BREDS) is a two year study to determine the prevalence of vision problems in an early school age population with reading difficulty.
- Conditions
- Refractive Error, Visual Impairment, Convergence Insufficiency, Reading Disabilities
- Trial name
- BREDS (NCT02607384)
- Testing
- Eyeglass wearing, Orthoptic exercises, Specialist referral
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Parent-Child Relations, Meals
Parent-Mediated Intervention for Families With Children With Autism and Feeding Challenges, Australia Cohort
The goal is to expand a parent-mediated intervention for feeding challenges in children with autism with an Australian cohort, building on recent research and current successful models already being used.
- Conditions
- Parent-Child Relations, Meals, Autism Spectrum Disorder
- Trial name
- NCT05852548
- Testing
- Parent-Mediated Intervention
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Autism Spectrum Disorders
Examining the Efficacy of Mattress Technology in Improving the Sleep Quality of Children With ASD
The purpose of the present study is to evaluate the tolerability and efficacy of the Sound To Sleep System™ in improving the sleep quality of children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02739321
- Testing
- Sound to Sleep System
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
ADHD
Effects of Noise Cancelling Headphones on Neurocognitive and Academic Outcomes in ADHD
The purpose of this study is to evaluate performance on the Attention Deficit Hyperactivity Disorder ( ADHD) Battery of the Cambridge Automated Neuropsychological Test Battery (CANTAB), including spatial working memory…
- Trial name
- NCT03216512
- Testing
- Use of Noise Cancelling Headphones
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Duke University
Autism Spectrum Disorder
Training and Implementation of RUBI in Community Mental Health Settings
This project is focused on evaluating outcomes related to this statewide clinical training effort in the RUBI parent training program.
- Trial name
- NCT05742464
- Testing
- RUBI
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
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