Clinical trials: Neurodevelopmental Disorders
Autism Spectrum Disorder
The Real World Study of Autism Spectrum Disorder in China
The investigators conduct the real world study to explore mechanisms of autism based on multi-modal data.
- Trial name
- NCT04358744
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Autism Spectrum Disorder
Adaptation of the NEAR Cognitive Remediation Method to Child and Adult Autism by Including Social Scenarios and Skills
The investigators currently provide the NEAR method (neuropsychological educational approach to cognitive remediation) for people with neurocognitive difficulties, without distinguishing between ASD and schizophrenia.
- Trial name
- NEAR-TSA (NCT05786898)
- Testing
- NEAR-TSA
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier St Anne
Intellectual Disability, Autism
Sensors for Communication for Persons Who Cannot Communicate Unequivocally
Some persons with intellectual disability or comprehensive cerebral palsy cannot communicate unequivocally how they are, how they react to situations and people, whether they are in pain or experience discomfort, anger or fear.
- Conditions
- Intellectual Disability, Autism, Cerebral Palsy
- Trial name
- NCT04199299
- Testing
- Heart rate and respiration rate sensors
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- University of Oslo
Autism, Neuroleptic Treatment
Use of Pharmacogenetics in the Treatment of Children With Autistic Spectrum Disorders
Children with autism are often treated with psychiatric drugs. These medications have been shown to improve their language and social function, and are important in improving their quality of life.
- Trial name
- NCT00859664
- Testing
- Genotyping of Cytochrome P450
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Assaf-Harofeh Medical Center
ADHD
Ongoing Tai Chi Training for Children With ADHD
Attention Deficit Hyperactivity Disorder (ADHD) has tremendous individual and societal impact, and the effectiveness of current standard treatments is limited.
- Trial name
- NCT03434509
- Testing
- Continuous Tai Chi and Mindful Movement classes
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Child Development Disorder, Post Partum Depression
Optimization of Mother-child Dyad Follow-up by a Multidomain Application: Real-world Cross Sectional Study
After birth, the mother-child dyad can be impacted by issues which are usually under-detected or detected at early stage. Among these issues, neurodevelopmental disorders (NDD) such as autism spectrum disorder are common and…
- Trial name
- MALO_2 (NCT05215028)
- Testing
- web-application
- Where
- France
- Volunteers
- 4,346 people
- Sponsor
- Weprom
ADHD - Attention Deficit Disorder With Hyperactivity
Sustained Endogenous Attention Deficits in Attention Deficit Hyperactivity Disorder
Subjects with ADHD may exhibit deficits in sustained internal attention. The "Sustained-Paced Finger Tapping" test was recently developed and experimentally used in international literature to assess sustained internal attention…
- Trial name
- NCT06900400
- Testing
- Sustained-Paced Finger Tapping" (Petilli et al., 2018)
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
MYT1L Syndrome
MYT1L Syndrome: a Rare Paediatric Genetic Syndrome Responsible for a Neurodevelopmental Disorder
MYT1L syndrome is a rare genetic syndrome, recently described in 2011, with paediatric onset, responsible for a neurodevelopmental disorder combining psychomotor retardation, learning difficulties and/or intellectual development…
- Trial name
- MYT1L (NCT07008612)
- Testing
- Patients with a genetic syndrome linked to the MYT1L gene, Patients with a neurodevelopmental disorder of genetic origin but not linked to MYT1L
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Rouen
Developmental Disability
Occupational Performance Coaching With Parents of Young Children With Developmental Disability
Participation in community activities allows children to meet friends, learns new skills, fosters independence, and paves the foundation for lifelong health.
- Trial name
- NCT04796909
- Testing
- Occupational Performance coaching, Parent consultation
- Where
- 3 sites in Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Challenging Behavior
A Single-Arm Pilot Trial for Mitigating Relapse of Severe Problem Behavior
The goal of this study is to improve how we teach self-control and communication skills to children and adolescents with challenging behaviors.
- Trial name
- NCT06732219
- Testing
- Functional Communication Training, Extinction-Correlated Stimuli, Caregiver Fading
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Auburn University
Attention Deficit Disorder With Hyperactivity, Neurodevelopmental Disorders
tES Modalities for the Treatment of ADHD
This project investigates the efficacy of transcranial electrical stimulation (tES) modalities, specifically transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), for treating…
- Trial name
- NCT06974136
- Testing
- transcranial electrical stimulation
- Where
- Iran
- Volunteers
- 45 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Autism Disorder
TRIal of PPF3 vs. PlaCEbo in the TReatment of Children and AdolescenTs With NeurOdeveloPmental DisorderS
A Randomized Placebo-Controlled TRIal of PPF3 vs. PlaCEbo in the TReatment of children and AdolescenTs with NeurOdeveloPmental DisorderS
- Trial name
- TRICERATOPS (NCT07893964)
- Testing
- PPF3
- Where
- 4 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Early Detection of Autism Spectrum Disorder in Children
Rationale: Autism Spectrum Disorder (ASD) is defined by deficits in social interaction and communication identified before the age of 3 years.
- Trial name
- NCT01646866
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Obsessive-Compulsive Disorder
Characterization of Childhood-Onset Obsessive-Compulsive Disorder
The purpose of this study is to learn more about Obsessive-compulsive Disorder (OCD) in children. OCD usually has a slow onset, and symptoms that may remain at a stable level over time.
- Trial name
- NCT00044239
- Where
- 4 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Attention Deficit Hyperactivity Disorder Symptoms
Implementation Strategy Resource Package for Behavioral Classroom Interventions: Pilot Test
The purpose of this study is to pilot test for feasibility and initial promise an implementation strategy resource package that aims to support teachers in using behavioral classroom management interventions for children with…
- Trial name
- NCT05489081
- Testing
- Positive Behavior Management Toolkit
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Autism Spectrum Disorder
Intestinal Microbiota, Tryptophan and Autism
Autism Spectrum Disorder refers to complex neuro-developmental disorders that affect social communication and behavioral adaptation.
- Trial name
- MTA (NCT03751930)
- Testing
- Samples
- Where
- 2 sites in France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Autistic Disorder
Research in Autism: Parent Intervention
The purpose of this research project was to systematically compare two widely used types of intervention programs for children with autism within a parent training model.
- Trial name
- NCT01258465
- Testing
- Pivotal Response Training, Picture Exchange Communication System
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Diego
ADHD - Attention Deficit Disorder With Hyperactivity
ADRIS Driving Simulator for Adolescents With Attention Deficit and Hyperactivity Disorder
This study aims to evaluate a new driving simulator, called ADRIS 2.1, developed for adolescents aged 13-18 years with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- ADRIS-ADHD (NCT07478458)
- Testing
- ADRIS-ADHD
- Where
- 2 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istituto Giannina Gaslini
Neurodevelopmental Disorders
Individual Neurophysiological Sensory Profiles in People With and Without Neurodevelopmental Disorders
The goal of this observational study is to evaluate intra-individual neurophysiological variability in children and adults with and without NeuroDevelopmental Disorders (NDD), for several sensory modalities and types of…
- Trial name
- SensAUry (NCT07542977)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Autism
Fluoxetine Essay in Children With Autism
This study is a comparative, double blind, placebo controlled trial of 6-months duration designed to evaluate 1) the effects of fluoxetine in 5 to 12 years old autistic children, 2) the effects of fluoxetine on serotoninergic…
- Trial name
- FAIR (NCT00873834)
- Testing
- fluoxetine
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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