Clinical trials: Neurodevelopmental Disorders
Tourette Syndrome, Tourette Syndrome in Children
Tourette Discrimination (TD) Stigma Scale
The goal of this qualitative study is to understand the challenges of stigmatization and discrimination in children and young adults with Chronic Tic Disorders (CTD), including Tourette Syndrome.
- Conditions
- Tourette Syndrome, Tourette Syndrome in Children, Tourette Syndrome in Adolescence, Tic Disorder, Childhood
- Trial name
- TD (NCT05696769)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Wake Forest University Health Sciences
Autism Spectrum Disorder
Effect of PECS in Improving Oral Hygiene Status Among Preschool Chidren
Background: Oral health is an important part of overall health of the children and precisely it is additionally imperative for children who need out of the ordinary or special health care.
- Trial name
- PECS (NCT06588062)
- Testing
- Picture Exchange Communication System (PECS)
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Autism Spectrum Disorder (ASD), Joint Attention
Joint Attention Processing in Social Threat Scenarios
This study set up two experiments using the free viewing video paradigm. By setting up social threat scenarios induced by humans (Experiment 1) and non social threat scenarios induced by objects (Experiment 2), combined with eye…
- Trial name
- NCT07582757
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
ADHD, Diet Modification
The Feasibility of a Dietary Intervention in Children With ADHD
The aim is to conduct a feasibility pilot study of a dietary intervention designed to optimise gut bacteria in children diagnosed with ADHD.
- Trial name
- NCT03737877
- Testing
- Diet modification
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- St Mary's University College
Speech Sound Disorder
Intensive Speech Motor Chaining Treatment for Residual Speech Sound Disorders
The goal of this randomized-controlled trial is to compare distributed treatment schedules and intensive treatment schedules in 84 school-age children with residual speech sound disorders.
- Trial name
- iChain (NCT05929859)
- Testing
- Speech Motor Chaining
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Syracuse University
ADHD
Adherence to Stimulant Treatment in Attention-Deficit Hyperactivity Disorder (ADHD) Patients (ASTA)
This study determined to measure non-adherence assessed by the number of non-adherent days during the clinical trial of 100 days using the Medication Event Monitoring System (MEMS).
- Trial name
- ASTA (NCT00852059)
- Testing
- Immediate release methylphenidate (Medikinet®), Extended release methylphenidate (Medikinet retard®)
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- Prof. Huss
Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS)
Transcranial Direct Current Stimulation in Children With Autism Spectrum Disorder
Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade.
- Conditions
- Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS), Electroencephalography
- Trial name
- NCT06880159
- Testing
- tDCS with computerized cognitive training
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
ADHD, Attention Deficit Hyperactivity Disorder
Phase 3 Efficacy and Safety Fixed-Dose Study in Pediatrics (6-17) With ADHD Using CTx-1301
A Phase 3, randomized, double-blind, placebo-controlled, multi-center, fixed-dose, parallel-group efficacy and safety study in a pediatric population (6-17) with Attention-Deficit/Hyperactivity Disorder (ADHD) using CTx-1301…
- Conditions
- ADHD, Attention Deficit Hyperactivity Disorder, ADHD - Combined Type, Attention Deficit Hyperactivity Disorder Combined
- Trial name
- NCT05286762
- Testing
- CTx-1301-Dexmethylphenidate 12.5 mg (titration only), CTx-1301-Dexmethylphenidate 18.75mg (randomized fixed dose), CTx-1301-Dexmethylphenidate 25mg (randomized fixed dose)
- Where
- 24 sites in United States
- Volunteers
- 103 people
- Sponsor
- Cingulate Therapeutics
Physical Exercise, Sleep Disturbance
Treatment of Sleep Disturbance in Children With ASD
This RCT study aims to compare effectiveness physical exercise and melatonin supplement on treating sleep disturbance in children with ASD.
- Conditions
- Physical Exercise, Sleep Disturbance, Autism Spectrum Disorder, Melatonin Deficiency
- Trial name
- NCT04878198
- Testing
- Jogging program, Melatonin supplement intervention
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- Education University of Hong Kong
Autism Spectrum Disorders
A Pilot Study of Riluzole Versus Placebo in the Treatment of Children and Adolescents With ASD
This study will examine the potential efficacy and safety of riluzole for core and associated symptom domains of autism and will explore biological markers of safety and treatment response.
- Trial name
- RILISE (NCT01661855)
- Testing
- Riluzole
- Where
- 3 sites in Canada
- Volunteers
- 58 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Neonatal Seizures
Prophylactic Phenobarbital After Neonatal Seizures
The treatment of infants with medications after their seizures have stopped is very variable. No one knows if continuing treatment with phenobarbital for up to several months is helpful or harmful.
- Trial name
- PROPHENO (NCT01089504)
- Testing
- phenobarbital
- Where
- 18 sites in United States
- Volunteers
- 13 people
- Sponsor
- University of Rochester
Child Development Disorder
Craniosacral Therapy Improves Infant Neurodevelopment
Craniosacral exploration and therapy is one of the innovative palpation and treatment techniques in specialized physiotherapy, which can contribute in an efficient, subtle and sudden way to the detection of dysfunctions in the…
- Trial name
- NCT05340049
- Testing
- Academic behavioral intervention of teachers, Therapy sessions
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Clinica Gema Leon
Bipolar Disorder, Attention Deficit Disorder With Hyperactivity
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls
The purpose of this research is to learn more about how children with mental health problems, including bipolar disorder (BD), attention deficit hyperactivity disorder (ADHD), and generalized anxiety disorder (GAD), differ from…
- Conditions
- Bipolar Disorder, Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder Without Hyperactivity, Generalized Anxiety Disorder
- Trial name
- BBPP (NCT01570426)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Attention Deficit Disorder With Hyperactivity (ADHD), Yoga
Effects of Yoga in Children With Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder (ADHD) is characterized by symptoms of inattention, impulsivity, and hyperactivity. Due to the core symptoms of ADHD, more than 30-50% of children with the disorder may experience impaired…
- Conditions
- Attention Deficit Disorder With Hyperactivity (ADHD), Yoga, Motor Skills
- Trial name
- NCT07076576
- Testing
- Yoga Training
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Pamukkale University
Attention Deficit Hyperactivity Disorder
Intervention for Teens With ADHD and Substance Use
Individuals with ADHD are at markedly high risk for increased substance use and Substance Use Disorder (SUD). Given the strong evidence for the negative trajectory of individuals with co-occurring ADHD and substance use…
- Trial name
- NCT02502799
- Testing
- Brief Early Intervention, Parent Training with Adolescent Cognitive Behavioral Therapy, Methylphenidate
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Florida International University
Attention Deficit Hyperactivity Disorder
CONCERTA Lab School Study
The purpose of this trial is to determine if the study medication, CONCERTA (methylphenidate HCl), is safe and effective in improving academic performance and behavior in children with Attention Deficit Hyperactivity Disorder…
- Trial name
- NCT00799487
- Where
- 3 sites in United States
- Volunteers
- 89 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Tourette Disorder, Tic Disorders
Evaluating the Efficacy and Safety of Yi-Gan San in Children and Adolescents With Tourette's Disorder
Yigansan was used in Ming dynasty by Xue Kai as a remedy for restlessness and agitation in children. We expect that the total YGTSS scores of Yigansan-treated subjects will be significantly reduced compared to that of…
- Trial name
- NCT03564132
- Testing
- Yigansan
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- China Medical University Hospital
ADHD, Bipolar Disorder
Concerta in the Treatment of ADHD in Youth and Adults With Bipolar Disorder
The objective of this study is to investigate the safety and effectiveness of Concerta in the treatment of children (ages 5 to 17 years old) and adults (ages 18 to 55 years old) with Bipolar I, Bipolar II and Bipolar Spectrum…
- Trial name
- NCT00181987
- Testing
- methylphenidate HCl (Concerta)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Massachusetts General Hospital
Autism
A Trial of CM-AT in Children With Autism
The purpose of this study is to determine whether CM-AT is safe and effective in treating the core symptoms of autism.
- Trial name
- CM-AT (NCT00881452)
- Testing
- CM-AT
- Where
- 19 sites in United States
- Volunteers
- 182 people
- Sponsor
- Curemark
Epilepsy, Intellectual Disabilities
Effect of the EpiSchool-M App on Teachers' Epilepsy Knowledge, Attitudes, and Self-Management
The aim of this study was to determine the effects of the training given to the teachers of children with intellectual disabilities with the "Epilepsy Management at School Mobile Health Application" and the "Digital Epilepsy…
- Conditions
- Epilepsy, Intellectual Disabilities, Teacher Training, Mobile Applications
- Trial name
- EpiSchool-M (NCT06807047)
- Testing
- Epilepsy Management at School Mobile Health Application, Digital Epilepsy Education Guide
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kafkas University
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