Clinical trials: Neurodevelopmental Disorders
Autism Spectrum Disorder
Telehealth Intervention for Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is one of the most frequently occurring childhood-onset neurodevelopmental disorders affecting 1 in every 54 children.
- Trial name
- NCT04832152
- Testing
- OT4ASD
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Autism Spectrum Disorders
Single Dose Double-blind, Placebo-controlled Cross-over (SDDBPCCO) Shiftability Study, Will be Followed by a 10-week Open-label Study With Arbaclofen (4 Weeks of Titration and Then 6 Weeks of Active/Stable Treatment). The Effects of Arbaclofen on Target EEG and ERG Metrics Will be Associated With th
study with arbaclofen (4 weeks of titration and then 6 weeks of active/stable treatment). The effects of arbaclofen on target EEG and ERG metrics will be associated with the clinical response in measures of social and general…
- Trial name
- NCT07655115
- Testing
- Arbaclofen
- Where
- 5 sites in France, Spain
- Volunteers
- 103 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Smith-Magenis Syndrome, Autism Spectrum Disorder
Smith Magenis Syndrome and Autism Spectrum Disorders
Autism Spectrum Disorders (ASD) are a neurodevelopmental disorder. Their prevalence is estimated at around 0.4% of the general population worldwide.
- Trial name
- SMS/TSA (NCT05116904)
- Testing
- Assessment
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Children, Only, Vestibular Disorder
Vestibular and Postural Function in Children Suspected of Balance Disorders
The goal of this prospective cohort study is to investigate the vestibular function in children suspected of balance disorders, and to follow up on their balance progressions after rehabilitation.
- Conditions
- Children, Only, Vestibular Disorder, Vestibular Function Disorder, Development Delay
- Trial name
- VASIC (NCT06229704)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Gødstrup Hospital
Attention-deficit/Hyperactivity Disorder
Time Perception Deficits and Attention-Deficit/Hyperactivity Disorder
Background: Literature has documented that children with attention-deficit/ hyperactivity disorder (ADHD) have difficulties in time management by manifesting with difficulties making plans, organizing tasks and activities, and…
- Trial name
- NCT00491647
- Where
- Taiwan
- Volunteers
- 258 people
- Sponsor
- National Taiwan University Hospital
Inguinal Hernia, Premature Birth of Newborn
Timing of Inguinal Hernia Repair in Premature Infants
The purpose of this study is to determine whether early (before NICU discharge) or late (55-60 weeks post-menstrual age) inguinal hernia repair is safer for premature infants who have an inguinal hernia.
- Trial name
- NCT01678638
- Testing
- IH repair before NICU discharge, IH repair at 55-60 weeks post-menstrual age
- Where
- 40 sites in United States
- Volunteers
- 338 people
- Sponsor
- Vanderbilt University Medical Center
ADHD, Autism
Trial to Assess the Pharmacokinetics, Safety, Tolerability of Oral Brexpiprazole in Children (6 to <13 Years Old) With Central Nervous System Disorders
A study to assess pharmacokinetics, safety and tolerability of brexpiprazole in children ages 6 to <13 years with CNS disorders.
- Conditions
- ADHD, Autism, Bipolar I Disorder, Conduct Disorder
- Trial name
- NCT03292848
- Testing
- Brexpiprazole
- Where
- 9 sites in United States
- Volunteers
- 24 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Adjunctive Celecoxib in Childhood-onset OCD Study
This is a randomized, controlled, single-centre phase II superiority trial to determine the efficacy of 12 weeks of celecoxib (50 mg or 100 mg orally twice daily, dosed based on weight) compared to placebo as an adjunct to…
- Trial name
- ACE-OCD (NCT04673578)
- Testing
- Celecoxib
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Very Low Birth Weight Infants
Efficacy of Multiple Strain Probiotics Reduces the Neurobehavioral Disorder in Premature Very Low Birth Weight Infants
The management protocols, clinical practices, equipment, infrastructure, and key personnel in NICU are unchanged during the study period.
- Trial name
- NCT03858816
- Testing
- Mixture probiotics
- Where
- Taiwan
- Sponsor
- China Medical University Hospital
Autism Spectrum Disorder
Brain Hero® Neurofeedback Training (With the Device Brainhero 2019, Type 201)
The study investigates the feasibility and the effects of training at home with personalised neurofeedback in children with an autism spectrum diagnosis and comorbidities.
- Trial name
- NCT05444816
- Testing
- Personalised Neurofeedback training at home
- Where
- 2 sites in Austria
- Volunteers
- 21 people
- Sponsor
- Brainhero GmbH
Attention Deficit Hyperactivity Disorder (ADHD)
Prediction of ADHD in Children Using Pedobarographic and Postural Data
The aim of this study is to investigate the potential of postural control and plantar pressure data in predicting Attention Deficit Hyperactivity Disorder (ADHD) in middle school students using machine learning methods.
- Trial name
- NCT07180758
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biruni University
Attention Deficit Hyperactivity Disorder, Dyslexia
Implementation of Climb Up Program for Children With Attention Deficit Hyperactivity Disorder (ADHD) and Dyslexia in a School in India
A multimodal intervention was rolled out at a large public school in Najibabad, Uttar Pradesh (UP). The program identified elementary school children with ADHD and Dyslexia using standard screening of all children who had…
- Trial name
- ClimbUp (NCT01012778)
- Testing
- Climb Up ADHD and Dyslexia Program
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Climb Up Kids
Attention Deficit Disorder With Hyperactivity, Executive Function Disorder
Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of ADHD in Children.
A multi-center, randomized controlled trial is being conducted to investigate the efficacy of a novel digital therapeutics (DTx) program that utilizes a cross-training approach between neurofeedback training and executive…
- Trial name
- ADHD (NCT06369714)
- Testing
- Concerta, Digital therapeutics
- Where
- 2 sites in China
- Volunteers
- 210 people
- Sponsor
- Lei Lei, MD
Attention Deficit Hyperactivity Disorder
a Case-control Study of the Association Between Heavy Mental and Children With Attention Deficit Hyperactivity Disorder in Korea
Heavy metal has been reported that it can cause attention deficit and behavioral disturbance. The investigators hypothesis is that heavy metal is associated with children with attention deficit/hyperactivity disorder(ADHD).
- Trial name
- NCT01447004
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Autism Spectrum Disorders
Investigating Phenotypic Profiles of Children and Adolescents With ASD
The purpose of this study is to provide a detailed description of language and cognitive profiles found among children and adolescents diagnosed with autism spectrum disorders (ASD).
- Trial name
- Phenotyping (NCT02700113)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Boston University Charles River Campus
Autism Spectrum Disorder
Study 1 Replication and Extension of Prior Work
The goal of this research is to explore abilities to learn word meanings from overheard conversations in children with ASD (and, as a control, typically developing children).
- Trial name
- NCT04166591
- Testing
- Overheard Speech, Addressed Speech
- Where
- 2 sites in United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- New York University
Dyslexia
Training Second-grade Dyslexic Students Using a Computerized Program in Assiut, Egypt
Dyslexia is a specific learning disability that is neurological in origin. It is characterized by difficulties with accurate or fluent word recognition, by poor spelling and decoding abilities, difficulty reading words in…
- Trial name
- Dyslexia (NCT04642859)
- Testing
- Computerized Cognitive abilities training battery for reading (CATB-R)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Assiut University
Autism Spectrum Disorder
Assessing the Impact of Probiotic Supplementation in Children Diagnosed With Autism Spectrum Disorder: the PROBI-O-TISM Study
Children with autism spectrum disorder (ASD) present with stereotyped behaviors and often with comorbidities including gastrointestinal symptoms and sleep disturbances.
- Trial name
- (PROBI-O-TISM) (NCT06906068)
- Testing
- Three strains of Lactobacillus: L. acidophilus CL1285®, L. casei LBC80R® and L. rhamnosus CLR2®
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Valérie Marcil
Health-Related Behavior, Quality of Life
PODER Familiar: Health Promotion for Latino Families of Children With IDD
The goal of this clinical trial is to test a culturally tailored health promotion intervention for children with IDD and their families.
- Conditions
- Health-Related Behavior, Quality of Life, Psychological Distress, Diet, Healthy
- Trial name
- PODER (NCT05713617)
- Testing
- PODER Familiar
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Autism Spectrum Disorder
Play Therapy With Gamified Biofeedback in Children With Autism Spectrum Disorder
This clinical trial tests whether combining regular play therapy with gamified biofeedback helps children with autism spectrum disorder better regulate their emotions and improve social skills, compared to play therapy alone.
- Trial name
- NCT07322640
- Testing
- Gamified Biofeedback, Play Therapy, Deactivated Biofeedback
- Where
- Brazil
- Volunteers
- 68 people
- Sponsor
- Luiz Alexandre Viana Magno
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