Clinical trials: Neurodevelopmental Disorders
Cerebral Palsy, Dyskinetic
Family-Centered Physiotherapy in Dyskinetic Cerebral Palsy
This study aimed to examine the impact of family centered, goal-oriented physiotherapy and rehabilitation on body function, activity, participation, and quality of life in severely affected children with dyskinetic cerebral palsy…
- Trial name
- NCT06532513
- Testing
- Family-Centered Goal-Oriented Physiotherapy and Rehabilitation Application
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Child Mental Disorder, Anxiety Disorders
Youth Metacognitive Therapy Feasibility Trial
One in eight children and young people (CYP) suffer mental health problems needing support or treatment and 5% have more than one such problem.
- Conditions
- Child Mental Disorder, Anxiety Disorders, Depression
- Trial name
- YoMETA (NCT05260060)
- Testing
- Treatment as usual: Control, Group Metacognitive Therapy (Group-MCT): Experimental
- Where
- United Kingdom
- Volunteers
- 95 people
- Sponsor
- University of Manchester
ADHD
Genetic Analysis of Attention Deficit Hyperactivity Disorder (ADHD)
Attention Deficit Hyperactivity Disorder (ADHD) is the most common behavioral disorder in childhood, affecting 3-5% of children between the ages of 7 and 17. Family studies suggest that there is a genetic component to ADHD.
- Trial name
- NCT00046059
- Where
- 2 sites in United States
- Volunteers
- 3,481 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Attention Deficit Hyperactivity Disorder
A Comparative Effectiveness Study Evaluating OROS Methylphenidate HCl, Ritalin (Methylphenidate HCl), and Placebo for the Treatment of Attention Deficit Hyperactivity Disorder in Children
The purpose of this study is to compare the effectiveness (onset of effect, time to loss of effect, and overall efficacy) of methylphenidate given as an OROS® (methylphenidate HCl) formulation, compared to immediate-release…
- Trial name
- NCT00269789
- Testing
- Ritalin, OROS Methylphenidate HCl
- Sponsor
- Alza Corporation, DE, USA
Autistic Spectrum Disorder
Nutritional Status and ASD Severity of Autistic Spectrum Disorder Children in Addis Ababa, Ethiopia; Case Control Study
The study conducts a case control analysis of the nutritional status and intake of autistic spectrum disorder diagnosed children as compared to typically developing children in Addis Ababa, Ethiopia.
- Trial name
- ASD (NCT05515913)
- Testing
- Nutritional status, Eating behavior, Urine iodine concentration
- Where
- Ethiopia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Addis Ababa University
Autism Spectrum Disorder, Behavior Problem
A Crisis Prevention Program for Youth With Autism
Mental health crises involve acute psychiatric states, such as aggression and/or self-injury, which can result in harm to self or others.
- Trial name
- NCT05681143
- Testing
- Crisis Prevention Arm, Control
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autism, Autism Spectrum Disorder
Trial of Cannabidiol to Treat Severe Behavior Problems in Children With Autism
There are very few treatments that are effective in reducing severe behavioral problems associated with autism. These behaviors include aggressive and self-harm behaviors, frequent repetitive behaviors and severe hyperactivity.
- Trial name
- NCT04517799
- Testing
- Epidiolex
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Diego
Adult ADHD
Efficacy of Concerta in Treating ADHD in Mothers of Children With ADHD
This study involves a 7 week dose-response trial of Concerta™ methylphenidate for mothers of children with ADHD who have ADHD themselves.
- Trial name
- NCT00318981
- Testing
- Concerta
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Maryland, College Park
Selective Mutism
What Treatment Works for Children With Selective Mutism?
The purpose of this pilot study is to explore the outcome of a manual based treatment for children with Selective Mutism
- Trial name
- NCT00554749
- Testing
- Interventions at home, in the kindergarten/school
- Where
- Norway
- Volunteers
- 7 people
- Sponsor
- Regionsenter for barn og unges psykiske helse
Attention Deficit Hyperactivity Disorder
Effectiveness Study of Videoconferencing on Teaching Parent Training Skills to Parents of Children With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to evaluate the effectiveness of group parent training taught through videoconferencing on ADHD treatment via a comparison between participants using traditional face-to-face parent training sessions…
- Trial name
- NCT01161719
- Testing
- parent training
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Davis
Autism Spectrum Disorder, Developmental Disabilities
A Self-Instructional Online Program for Early Childhood and Elementary Teachers Supporting Autistic Children and Children With Developmental Delays
The goal of this clinical trial is to evaluate the preliminary effectiveness and acceptability of a self-instructional, web-based teacher training program designed to support the development of autistic children and children with…
- Conditions
- Autism Spectrum Disorder, Developmental Disabilities, Developmental Delay, Teacher Training
- Trial name
- SEED (NCT07524192)
- Testing
- SEED Online Self-Instructional Program, Comparison Educational Materials (Kit for Kids)
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Boin Choi
Attention Deficit Disorder
Study of the Efficacy of Sulforaphane in Children Aged 6 to 12 With Attention Deficit Disorder With or Without Hyperactivity
ADHD is a neurodevelopmental disorder. It is the most common neurodevelopmental disorder in children and adolescents. Its prevalence is estimated at 5.9% in this population.
- Trial name
- SulfoTDAH (NCT06594536)
- Testing
- Sulforaphane
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Developmental Language Disorder
Efficacy of a Pragmatic Intervention to Improve Adaptation to Context and Interlocutor
Patients with Developmental Language Disorder (DLD) or Autism Spectrum Disorder (ASD) have communicational difficulties to adapt their language to context and to interlocutors.
- Trial name
- NCT05127863
- Testing
- social communication intervention (pragmatic)
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Université Catholique de Louvain
Anxiety Disorders
Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety
Anxiety is the most common mental health problem in children and adolescents. This two-phased study will test the effects of an experimental computerized intervention aimed at reducing threat-based thinking (i.e., interpretation…
- Trial name
- NCT04245501
- Testing
- Cognitive Bias Modification for Interpretations (CBM-I), Interpretation Control Condition (ICC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Denver
Autism Spectrum Disorder, Life Change Events
Animal-assisted Resilience Training for Children With Stressful Life Events or Autism Spectrum Disorder
The goal of this clinical trial is to learn about the effects of an animal-assisted resilience training in children who experienced stressful life events or who have a diagnosis of autism spectrum disorder.
- Trial name
- AART (NCT06025539)
- Testing
- Animal-assisted resilience training
- Where
- Switzerland
- Volunteers
- 107 people
- Sponsor
- University Hospital, Basel, Switzerland
ADHD, Asperger Syndrome
A Prospective Observational Study of Family-based Interventions for Children With Neuropsychiatric and/or Psychiatric Disorders
The purpose of this study is to examine the feasibility and the effects of family-based interventions for children (aged 5-12) with neuropsychiatric and psychiatric disorders in Finnish health care settings.
- Conditions
- ADHD, Asperger Syndrome, Child Behavior Disorders
- Trial name
- NCT02250339
- Testing
- LAKU family program, Etä-LAKU family program, Family therapy
- Where
- Finland
- Volunteers
- 230 people
- Sponsor
- Social Insurance Institution, Finland
Parental Stress, Communication Disorder, Childhood
Pediatric Research in the Outpatient Setting CoHort
Though primary care pediatricians (PCPs) and general practitioners solve 90% of children's health problems without referral to specialized care (about 10% of total health expenditures) there is little data on the common health…
- Conditions
- Parental Stress, Communication Disorder, Childhood, Development and Health
- Trial name
- PROS-CH (NCT07911228)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Attention Deficit Hyperactivity Disorder
A Study to Determine Effective and Tolerable Titration Scheme for OROS-Methylphenidate in Children With Attention-deficit Hyperactivity Disorder
The purpose of the study is to investigate the clinical benefit of switching children with ADHD from immediate-release methylphenidate (IR-MPH) to OROS-methylphenidate under the correct dosage conversion scheme.
- Trial name
- NCT00518232
- Testing
- OROS-methylphenidate
- Volunteers
- 520 people
- Sponsor
- Johnson & Johnson Taiwan Ltd
Autism Spectrum Disorder High-Functioning
Establishment of Social Skills Training Group in Adolescents With Autism Spectrum Disorder and Effectiveness Analysis
Autism spectrum disorders (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication and social interaction, and the presence of restricted, repetitive behavior and interests.
- Trial name
- NCT05341011
- Testing
- PEERS® Social Skills Training
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- National Taiwan University Hospital
Attention Deficit Hyperactivity Disorder
Study to Evaluate the Efficacy of Modafinil Treatment in Patients With Attention Deficit Hyperactivity Disorder (ADHD) Who Are Responders to Modafinil Treatment
The purpose of this study is to evaluate the continued efficacy of modafinil treatment, compared to placebo treatment, in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) who are responders to…
- Trial name
- NCT00343811
- Testing
- Modafinil
- Where
- 23 sites in United States
- Volunteers
- 120 people
- Sponsor
- Cephalon
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