Clinical trials: Neurodevelopmental Disorders
Attention Deficit Hyperactivity Disorder
Virtual Reality in Rehabilitation of Executive Functions in Children With Attention Deficit Hyperactivity Disorder.
Attention deficit hyperactivity disorder (ADHD) is caused by an abnormality in the development of the central nervous system. Children with attention and executive function difficulties often need long-lasting rehabilitation and…
- Trial name
- VREALFUN-ADHD (NCT06123741)
- Testing
- Parental Guidance, Virtual Reality Game
- Where
- Finland
- Volunteers
- 88 people
- Sponsor
- Merja Nikula
Attention Deficit Disorder With Hyperactivity (ADHD)
Healing Minds II: Biofeedback, Breathing Practices, Nutrition and Exercise Counseling in Children and Adolescents With ADHD
The Pediatric Healing Minds II intervention includes a biofeedback component, breathing practices nutrition and exercise counseling.
- Trial name
- NCT07180602
- Testing
- Heart Math Biofeedback Breathing Practices, Nutrition Counseling combined with Exercise Counseling
- Where
- United States
- Sponsor
- Hoskinson Health and Wellness Clinic
Conduct Disorder
Mentalization-based Training for Adolescents With Conduct Disorder (MBT-CD)
A feasibility and pilot trial to investigate the feasibility of a newly manualized psychotherapy "Mentalization-Based Training for Adolescents with Conduct Disorder (MBT-CD)"
- Trial name
- MBT-CD (NCT02988453)
- Testing
- MBT-CD
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Heidelberg University
ADHD, Autism
Dose Response Effects of Quillivant XR in Children With ADHD and Autism: A Pilot Study
The purpose of this study is to determine whether Quillivant XR is effective in the treatment of ADHD in children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02255565
- Testing
- Very Low Dose Quillivant XR, Low Dose Quillivant XR, Moderate Dose Quillivant XR
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Seattle Children's Hospital
Prematurity, Neurodevelopmental Disorders
Prevention of Developmental Delay and Xylitol (PDDaX) Study
The goals of this study are to: evaluate and validate the low-cost, transportable, easily-administered Malawi Developmental Assessment Tool (MDAT) for neurodevelopmental assessment of children aged 4-8 years old in Malawi, as…
- Trial name
- NCT05361122
- Testing
- Maternal Use of Xylitol Chewing Gum During Pregnancy, No Maternal Xylitol Chewing Gum Use During Pregnancy
- Where
- Malawi
- Volunteers
- 1,000 people
- Sponsor
- University of Washington
Social Phobia
Treatment of Childhood Social Phobia
This 4-year study will compare the long-term effectiveness of behavioral treatment, fluoxetine (Prozac®), and placebo for treatment of social phobia in children and adolescents.
- Trial name
- NCT00043537
- Testing
- Social Effectiveness Therapy for Children (SET-C), Fluoxetine
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Social Anxiety Disorder, Specific Phobia
Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment
The collection of patient self-report and diagnostic data will allow us to examine the efficacy of the treatment delivered in the McLean Anxiety Mastery Program.
- Conditions
- Social Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder, Panic Disorder
- Trial name
- NCT02305537
- Testing
- McLean Anxiety Mastery Program
- Where
- United States
- Volunteers
- 559 people
- Sponsor
- Mclean Hospital
Developmental Delay
Effects of Power Ball on Proximal Muscle and Refractive Errors in Developmental Delay.
When a child does not meet developmental milestones at the anticipated times, it is referred to as having a developmental delay. These benchmarks cover social, emotional, cognitive, physical, and communication abilities.
- Trial name
- NCT06461572
- Testing
- conventional therapy, conventional therapy along with standard therapy and stability exercises.
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Tourette Syndrome, Chronic Tic Disorder
Proof of Concept Study of an Oral Orthotic to Reduce Tic Severity in Chronic Tic Disorder and Tourette Syndrome
The purpose of this study is to assess the feasibility of a trial on an oral orthotic for reducing tic severity in children ages 7-25 years with Tourette syndrome (TS) or Chronic Tic Disorder (CTD).
- Trial name
- NCT02067819
- Testing
- Active Oral Orthotic Treatment
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Weill Medical College of Cornell University
Congenital CMV Infection
Evaluation of Long-term Efficacy of 4 to 6-month Course Antiviral Therapy for Neurodevelopmental Impairments Caused by Congenital Cytomegalovirus Infection
Title: Evaluation of Long-term Efficacy of 4-month versus 6-month Course Antiviral Therapy for Neurodevelopmental Impairment Caused by Congenital CMV Infection: A Multicenter, Randomized, Controlled, Non-inferiority Clinical…
- Trial name
- NCT07450365
- Testing
- Intravenous ganciclovir (6 mg/kg, twice daily) or oral valganciclovir (16 mg/kg, twice daily) was administered for a treatment course of 4 months., Patients received a 6-month course of anti-CMV therapy. The treatment regimen consisted of either intravenous ganciclovir (6 mg/kg, twice daily) or oral valganciclovir (16 mg/kg, twice daily).
- Volunteers
- 150 people
- Sponsor
- Hu Bofei
Attention Deficit Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder (ADHD) Brain Activity Changes to Psychostimulants
The purpose of this study is to examine the neural basis of response inhibition, working memory, and sustained attention in adolescents and adults with Attention-Deficit/Hyperactivity Disorder (ADHD), with particular emphasis on…
- Trial name
- NCT01310439
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Hartford Hospital
Attention-Deficit/Hyperactivity Disorder
Trigeminal Nerve Stimulation for Attention Deficit Hyperactivity Disorder (ADHD)
This proposal seeks to obtain preliminary data on the potential efficacy, tolerability, and feasibility of trigeminal nerve stimulation (TNS) as a treatment for Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT01388530
- Testing
- EMS 7500 Digital Muscle Stimulator
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Los Angeles
Developmental Delay
Head Start Family Navigator Intervention
Headstart (HS) is an early childhood education program for low-income children. Preliminary analyses of Hamilton County HS preschoolers with developmental concerns identified 26% with "severe concern" necessitating developmental…
- Trial name
- HeadStartNav (NCT03499405)
- Testing
- Family Navigator Intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Tourette Syndrome
National Gilles De La Tourette Study Group
Tourette syndrome is rare. In France, about 3000 patients have a severe form of the disease. The aim of this study is to collect clinical characteristics in 200 patients with Tourette syndrome.
- Trial name
- NCT00169351
- Where
- France
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Autism Spectrum Disorders
Parents Workgroup About Emotion Regulation
The purpose of this study is examine emotional regulation and reflective functioning in parents of children with Autism Spectrum Disorders (ASD) before and after an educational training (four sessions of group workshops).
- Trial name
- NCT02400177
- Testing
- emotion regulation training
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autistic Disorder, Developmental Disabilities
Evaluating Parent Delivered Interventions for Children With Autism
The investigators will assess the efficacy of parent delivered interventions in the treatment of social and communication deficits in children with autism.
- Trial name
- NCT01882153
- Testing
- Pivotal Response Training (PRT), PACE Therapy, PACE and PRT Hybrid
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
PRISM Intervention Study
This research study, Personalized, Responsive Intervention Sequences for Minimally Verbal Children with Autism (PRISM), is designed to maximize language outcomes for limited-language preschoolers, thereby lowering the risk of…
- Trial name
- NCT03883139
- Testing
- JASPER, DTT (Discrete Trial Training)
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Equine-assisted Occupational Therapy for Children With Autism Spectrum Disorder
Children with Autism Spectrum Disorder have difficulty engaging in activities. This study examined the effects of equine-assisted occupational therapy for 7 children with ASD ages 4 to 8 years.
- Trial name
- NCT02714101
- Testing
- Equine assisted occupational therapy
- Volunteers
- 8 people
- Sponsor
- University of Alberta
Severe Intellectual Disability
Molecular Diagnosis of Syndromic or Isolated Severe Intellectual Disability Using Whole Exome Sequencing : a Pilot Study
Evaluation of diagnostic whole exome sequencing in patients with syndromic or isolated severe intellectual disability without a molecular diagnostic, with suspected autosomal recessive inheritance, allowing accurate genetic…
- Trial name
- SHD-DI (NCT02862808)
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Autism Spectrum Disorder
Promoting Resilience in Teens With ASD
Interventions for Autism Spectrum Disorder (ASD) are almost uniformly costly and time-intensive, blunting dissemination of intervention and stymying opportunities to make scalable impact.
- Trial name
- PRITA (NCT04208425)
- Testing
- Project Personality, Sharing Feelings Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stony Brook University
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