Clinical trials: Neurogenic Bladder
Neurogenic Bladder Disorder, Bladder Dysfunction
Urinary Artificial Sphincter in Children
Retrospective monocentric study of the outcomes of patients with neurogenic bladder who had a urinary artificial sphincter before the age of 18 years old.
- Conditions
- Neurogenic Bladder Disorder, Bladder Dysfunction, Spina Bifida, Urinary Incontinence Due to Urethral Sphincter Incompetence
- Trial name
- SUAPED (NCT06734429)
- Testing
- Urinary Artificial Sphincter
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Clermont-Ferrand
Voiding Disorders, Overactive Bladder
Beta 3 Agonists in Treatment of Non-neurogenic Voiding Dysfunction in Children
A randomized clinical study to evaluate the safety and efficacy of using the Beta 3 agonist drug (Mirabegron) combined with standard behavioral therapy in comparison to using the anticholinergic drug (Solifenacin) combined with…
- Trial name
- NCT05240456
- Testing
- Beta3-Agonists, Adrenergic, Anticholinergic drug, Solifenacin
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Neurogenic Detrusor Overactivity
A Two-week Open-label Pharmacodynamic and Pharmacokinetic Study of Multiple Doses of a Darifenacin Liquid Oral Suspension in Children (2 - 15 Years) With Neurogenic Detrusor Overactivity
This study will evaluate the pharmacodynamics and pharmacokinetics of darifenacin liquid oral suspension in children, ages 2-15 years, with neurogenic detrusor overactivity.
- Trial name
- NCT00712322
- Testing
- Darifenacin
- Where
- 12 sites in United States, Colombia
- Volunteers
- 35 people
- Sponsor
- Warner Chilcott
Incontinence, Urge, Stroke
Evaluation of the Efficacy of Transcutaneous Tibial Nerve Stimulation on Post-Stroke Overactive Bladder
The goal of this clinical trial is to comparing the efficacies of different managements in patients with overactive bladder symptoms with stroke The main question it aims to answer are: Are pelvic floor training exercises and…
- Conditions
- Incontinence, Urge, Stroke, Neurogenic Bladder
- Trial name
- NCT06247033
- Testing
- Tibial Nerve Stimulation with TENS device, Pelvic muscle training exercise with bladder training
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Neurogenic Bladder, Detrusor Underactivity
A Comparative Analysis of Portable Bladder Scanner to Determine Age/ Volume Specific Accuracy in 0-6 Years of Children
As a part of the urodynamic studies, urinary catheterization is inserted to measure residual urine, however, it has shown to be an invasive procedure, cause urinary tract infection, and traumatic experience.
- Conditions
- Neurogenic Bladder, Detrusor Underactivity, Detrusor Overactivity
- Trial name
- NCT04543552
- Testing
- Bladder scan
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Hospital
Spinal Cord Injuries
Transcutaneous Spinal Cord Stimulation With Bladder and Pelvic Floor Muscle Training
Spinal Cord Injury (SCI) disrupts signals between the brain and the rest of the body, this includes signals needed to control the bladder and bowels.
- Trial name
- NCT05504200
- Testing
- Bladder and Pelvic Floor Muscle Training
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- RNOH RIC
Overactive Bladder, Incontinence, Daytime Urinary
Botulinum Neurotoxin Type A (BoNT-A) in Paediatric Non-neurogenic Therapy Resistant Overactive Bladder (OAB)
A non-intervention cohort study on the use of Botulinum Neurotoxin Type A (BoNT-A) in Paediatric Non-neurogenic Therapy Resistant Overactive Bladder (OAB). Primary endpoint was the reduction of urinary incontinence.
- Conditions
- Overactive Bladder, Incontinence, Daytime Urinary, Incontinence, Nighttime Urinary
- Trial name
- NCT06569342
- Testing
- Intradetrusor BoNT-A
- Where
- Denmark
- Volunteers
- 43 people
- Sponsor
- University of Aarhus
Spina Bifida
Nerve Rerouting Treatment for Neurogenic Bladder in Spina Bifida
The goal of this study is to evaluate a surgical procedure (operation) that reroutes lumbar to sacral nerves in the spinal column to improve the bladder's ability to empty properly in patients born with Spina Bifida.
- Trial name
- NCT01096459
- Testing
- Nerve Rerouting
- Sponsor
- Kenneth Peters, MD
Neurogenic Bladder Due to Spina Bifida (Disorder)
Sterile Single-use vs Reused Polyvinylchloride Catheter For Intermittent Catheterization In Neurogenic Bladder
The objective of the study is to determine whether single-use polyvinylchloride (PVC) catheters reduce urinary tract infections (UTI) compared to reused PVC catheters for patients with neurogenic bladder due to spina bifida that…
- Trial name
- Catheters (NCT03424499)
- Testing
- Single-use catheter, Reused catheter, Urine culture
- Volunteers
- 113 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Bladder, Neurogenic
PK/PD, Long-term Safety and Efficacy of Tamsulosin Treatment in Children With Neurogenic Bladder
Aims of this study is to characterize the pharmacokinetic/pharmacodynamic profile and evaluate the safety, efficacy and tolerability, of tamsulosin hydrochloride as treatment in children with a neuropathic bladder, over the…
- Trial name
- NCT00340704
- Testing
- tamsulosin hydrochloride
- Where
- 72 sites in United States, Belgium and 12 more
- Volunteers
- 143 people
- Sponsor
- Boehringer Ingelheim
Complications of Surgical Procedure, Neurogenic Bladder
Complications of Enterocystoplasty in Children
The goal of this observational study is to describe the complications in participants who underwent enterocystoplasty in childhood.
- Conditions
- Complications of Surgical Procedure, Neurogenic Bladder, Spina Bifida, Child, Only
- Trial name
- AVPED (NCT05840874)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Dr Christelle DESTINVAL
Neurogenic Urinary Bladder
Alfuzosin Treatment in Children and Adolescents With Neurogenic Urinary Bladder Dysfunction
The primary objective of the study was to evaluate the efficacy of Alfuzosin in comparison to Placebo on the detrusor Leak Point Pressure (LPP) in children and adolescents 2-16 years of age with elevated detrusor LPP of…
- Trial name
- ALFACHIN (NCT00549939)
- Testing
- Alfuzosin
- Where
- 18 sites in United States, Bulgaria and 16 more
- Volunteers
- 172 people
- Sponsor
- Sanofi
Neurogenic Bladder, Continent Cutaneous Urinary Diversion
Implantation of Continent Catheterizable Channel : Native Bladder or Enterocystoplasty ?
PURPOSE. To compare the results between two sites of implantation of the continent catheterizable channel (CCC): native bladder or enterocystoplasty. METHODS.
- Conditions
- Neurogenic Bladder, Continent Cutaneous Urinary Diversion, Mitrofanoff
- Trial name
- ICODE (NCT04922437)
- Testing
- Native bladder implantation, Enterocystoplasty implantation
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Central Hospital, Nancy, France
Neurogenic Bladder
Bilateral Comparison of Unilateral Sacral Neuromodulation Test Stimulation in the Treatment of Neurogenic Bladder
Neurogenic bladder (NB) is a general term for a series of lower urinary tract symptoms and complications caused by bladder and/or urethral dysfunction caused by nervous system lesions.
- Trial name
- NCT07505940
- Testing
- bilateral sacral nerve stimulation (BNS)
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Qilu Hospital of Shandong University
Neurogenic Bladder, Tethered Spinal Cord Syndrome
Urological Deterioration in Secondary Tethered Cord Syndrome and Clue to Detect It
Secondary tethered cord syndrome (STCS) has been diagnosed with signs of progressive deterioration in urological or neuroorthopedic systems following primary tethering surgery.
- Trial name
- NCT04483570
- Testing
- Redo-tethering operation
- Volunteers
- 54 people
- Sponsor
- Seoul National University Hospital
Neurogenic Incontinence, Dysfunctional Voiding
Treatment of Neurogenic Incontinence by Surgery to Cut the Filum Terminale
The target population of this study is children with primary or secondary daytime urinary incontinence, who have failed to improve adequately despite compliance with at least 6 months of standard medical therapy.
- Trial name
- NICNOC (NCT01465581)
- Testing
- Division of the filum terminal
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nemours Children's Clinic
Multiple Sclerosis, Urinary Bladder, Neurogenic
Urinary Disorders in Patients With Multiple Sclerosis: Invasive Vs Non-invasive Investigations.
The objective of the study is to describe the current status of MS patients with urinary disorders in Lebanon, and to demonstrate whether invasive investigations improve the management of these patients compared to an optimal…
- Conditions
- Multiple Sclerosis, Urinary Bladder, Neurogenic, Urodynamics
- Trial name
- NCT03336424
- Testing
- Non-invasive investigations, Invasive investigations
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Saint-Joseph University
Incontinence, Bladder Dysfunction
Bladder Neck Surgery in Children with Neurogenic Bladder
Surgical outcomes of bladder neck surgery in children with neurogenic bladder. Consequences on bladder voiding.
- Conditions
- Incontinence, Bladder Dysfunction, Spina Bifida, Neurogenic Bladder Disorder
- Trial name
- CERPED (NCT06734390)
- Testing
- Bladder Neck Surgery
- Where
- France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Clermont-Ferrand
Spina Bifida, Neurogenic Bladder
Use of a Diurnal Indwelling Urethral Catheter to Improve Quality of Life
This is an interventional study examining the effects of closed diurnal indwelling catheterization (CDIC) for neurogenic bladder management.
- Trial name
- NCT03573726
- Testing
- Closed diurnal indwelling catheter (CDIC)
- Volunteers
- 14 people
- Sponsor
- Shriners Hospitals for Children
Urinary Bladder, Neurogenic
Open-label Long-term Extension Study of Fesoterodine in Japanese Subjects With Neurogenic Detrusor Overactivity.
The purpose of this study is to investigate the safety and tolerability of fesoterodine following once daily long-term treatment in Japanese pediatric neurogenic detrusor overactivity (NDO) subjects.
- Trial name
- NCT02501928
- Testing
- Fesoterodine PR 4 mg, Fesoterodine PR 8 mg, Fesoterodine BIC 2 mg
- Where
- 7 sites in Japan
- Volunteers
- 12 people
- Sponsor
- Pfizer