Clinical trials: Neurological Condition
Dental Anxiety, Pain
Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this studio will be to evaluate the effectiveness of "Hands/Eyes/mouth" behavior management technique versus a conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02591797
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Cardenal Herrera University
Post Surgical Pain, Surgery
Mindfulness Surgical Pain Outcomes
This will be a prospective randomized study to evaluate novel, clinically feasible, easily deliverable, pragmatic ways of preemptively modifying known CPSP and behavioral risk factors for acute to chronic pain transitions in…
- Trial name
- MNF (NCT05838443)
- Testing
- Self-directed mindfulness utilizing a multi-sensor EEG-supported device with neurofeedback-assisted and technology-supported meditation, Provider-directed mindfulness, Conventional Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pain
The Effect of Two Different Non-pharmacologic Methods for Painandfear Relief During Blood Specimen Collection Inchildren
Introduction: Pain is defined as an unpleasant emotional and sensorial feeling that arises from any part of the body progresses with possible tissue damage and covers all past experiences of individuals.
- Trial name
- NCT05560074
- Testing
- Buzzy, DistrACTION® Cards
- Where
- Germany
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Epilepsy, Seizure
AI-Based Mobile Intervention on Medication Non-Adherence and Transition
This study aims to examine whether the AI-personalized version of the Medilepsy® app is more effective than the non-AI (standard version without AI personalization) can improve key outcomes, such as medical adherence and…
- Trial name
- NCT07445074
- Testing
- Medilepsy® Chatbot AI-Enhanced, Medilepsy® Chatbot Standard
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Central Florida
Pain, Procedural
Pain Assessment in the Perioperative Area
This study is mainly focusing on reducing the pain scores during IV cannulation in pediatric population in the preoperative period. Applying EMLA cream is a well-known fact world wide.
- Trial name
- EMLA (NCT04212208)
- Testing
- IV cannulation
- Where
- India
- Volunteers
- 120 people
- Sponsor
- All India Institute of Medical Sciences, Rishikesh
Pain, Postoperative, Scoliosis Idiopathic
Gabapentin and Chronic Post Surgical Pain
The purpose of this study is to investigate the effect of a common pain medication (gabapentin) on chronic postsurgical pain in pediatric patients who require surgery for idiopathic scoliosis.
- Trial name
- CPSP (NCT03867240)
- Testing
- Gabapentin
- Where
- United States
- Sponsor
- Emory University
Traumatic Brain Injury, Subarachnoid Hemorrhage
Comparison of Narcotrend and Cerebral Function Analysing Monitor in Intensive Care to Monitor Seizures and Deep Sedation
A study in the use of the Narcotrend depth of anaesthesia monitor to record a) seizures, and b) monitor a level of sedation referred to as 'burst suppression', in sedated patients in the adult and paediatric intensive care.
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Haemorrhage, Encephalitis
- Trial name
- NCT06067750
- Testing
- Narcotrend compared to Cerebral Function Analysing Monitor (CFAM)
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Venipuncture
The Effects of Aromatherapy on the Incidence and Severity of Acute Pain
The purpose of this research was to estimate feasibility of an aromatherapy pain management intervention to reduce pain and distress caused by venipunctures in a pediatric population.
- Trial name
- NCT03122574
- Testing
- Lavender Aromatherapy, Jojoba Aromatherapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Syncope, Chest Pain
Autonomic Monitoring in Neurocardiogenic Syncope
This is a prospective observational pilot study of suitability of autonomic monitoring via the VU-AMS device for prediction of neurocardiogenic syncope (NCS) in children referred to cardiopulmonary exercise testing (CPET) for a…
- Conditions
- Syncope, Chest Pain, Dyspnea
- Trial name
- ANSS (NCT05907018)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cardiac Arrest, Hypothermia
COOL-Trial: Outcome With Invasive and Non-invasive Cooling After Cardiac Arrest
Sudden cardiac arrest (SCA) remains one of the major leading causes of death. Cognitive deficits are common in survivors of SCA.
- Trial name
- COOL (NCT00843297)
- Testing
- Coolgard, ArcticSun, Conventional treatment
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Leipzig
Primary Dysmenorrhea
Menstrual Health Education's Impact on Knowledge, Attitudes and Self Care Behavior of Dysmenorrheal Adolescents
This study will be a randomized controlled trial. This study will be conducted in F G modal for girls' I/8-4, Federal Government College for Women and Islamabad Model College for Girls.
- Trial name
- NCT05315050
- Testing
- Educational session and Information Pamphlet, Information Pamphlet
- Where
- Pakistan
- Volunteers
- 138 people
- Sponsor
- Riphah International University
Hypospadias, Caudal Block
Ultrasound Guided Sacral Erector Spinae Plane Block Versus Ultrasound Guided Caudal Block in Pediatric Undergoing Hypospadias Surgery
Randomized, parallel-group, assessor-blinded clinical trial at Tanta University Hospitals comparing ultrasound-guided sacral erector spinae plane block (sESPB) versus ultrasound-guided caudal epidural block for postoperative…
- Conditions
- Hypospadias, Caudal Block, Erector Spinae Plane Block, Pain, Postoperative
- Trial name
- NCT07099560
- Testing
- Ultrasound-guided sacral erector spinae plane block (sESPB), Ultrasound-guided caudal epidural block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Cardiovascular Diseases, Coronary Disease
Coronary Heart Disease Incidence, Mortality, and Risk Factor Relationships
To determine the incidence, secular trends, and outcomes of coronary heart disease in the population of Rochester, Minnesota.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00005148
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Emergence Delirium, Anesthesia; Adverse Effect
Language During Inhalational Induction
The aim of this study is to compare the impact of common (standard of care) language vs positive language used by clinicians during inhalational induction of anesthesia on anxiety and negative behaviors in children.
- Trial name
- NCT06324955
- Testing
- Standard/common language during induction, Positive language during induction
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Boston Children's Hospital
Inhalation of Nitrous Oxide, Opioid Analgesic Adverse Reaction
Combination of Nitrous Oxide 70% With Fentanyl Intranasal for Procedural Analgosedation in Children
This study analyzes the analgesic efficacy and adverse events of nitrous oxide 70% combined with basic analgetics compared to nitrous oxide 70% with fentanyl intranasal for analgosedation for short and painful procedures in…
- Conditions
- Inhalation of Nitrous Oxide, Opioid Analgesic Adverse Reaction, Pain
- Trial name
- NCT02533908
- Testing
- Fentanyl intranasal, NaCl 0.9% intranasal
- Where
- Switzerland
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Anxiety, Pain
Colposcopy Anxiety and the Role of Pre-procedure Nursing Intervention
Colposcopy is essential for the diagnosis and prevention of cervical cancer. However, receiving screening results and being informed of the need to undergo a colposcopic examination are significant sources of anxiety for…
- Trial name
- NCT07092189
- Testing
- Pre-colposcopy counseling by a clinical nurse, Treatment as usual: regular call to schedule the appointment without pre-procedure conseilling
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Université de Sherbrooke
Blood Collection
Use of Acupressure, Aromatherapy, and Virtual Reality for Children in During Blood Collection Procedures
This study aims to evaluate the effects of acupressure, music listening, and virtual reality applications, which appeal to the senses of touch, hearing, and sight during blood sampling, on pain, fear, and anxiety levels in…
- Trial name
- NCT07400874
- Testing
- Acupressure, Listening Music, Virtual Reality
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Artvin Coruh University
Dental Pulp Exposure, Postoperative Pain
Diode Laser-Assisted Direct Pulp Capping Trial
This randomized controlled clinical trial evaluates whether adjunctive 808-nm diode laser therapy after direct pulp capping reduces postoperative pain and dentin hypersensitivity compared with conventional Biodentine treatment.
- Conditions
- Dental Pulp Exposure, Postoperative Pain, Dentin Hypersensitivity
- Trial name
- NCT07593508
- Testing
- Biodentine, 808-nm Diode Laser
- Where
- Vietnam
- Volunteers
- 56 people
- Sponsor
- Hue University of Medicine and Pharmacy
Fragile X Syndrome
Biomarker Testing and DNA Collection in Subjects Participating in Protocol 22001
The subjects that meet the inclusion and exclusion criteria and consent to participate in protocol 22001 will be offered participation in 22001A which will evaluate secreted protein before and after treatment with STX209 and…
- Trial name
- NCT00823368
- Testing
- STX209
- Where
- 11 sites in United States
- Sponsor
- Seaside Therapeutics, Inc.
Sickle Cell Disease, Pain
Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.
- Conditions
- Sickle Cell Disease, Pain, Acupuncture, Quantitative Sensory Testing
- Trial name
- NCT06725550
- Testing
- needling acupuncture, laser acupuncture
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
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