Clinical trials: Neurological Condition
Burn, Hydrotherapy
Virtual Reality, Pain, Clinical Outcomes, Hydrotherapy, Children, Burn
This study aims to evaluate the effect of virtual reality on pain and clinical outcomes during hydrotherapy for children with burn.
- Trial name
- NCT06160518
- Testing
- Virtual reality
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Matrouh University
Guillain-Barré Syndrome, Neuropathic Pain
Comparison Between Efficacy of Gabapentin and Carbamazepine in Neuropathic Pain of Guillain-Barré Syndrome Patients
This randomized controlled trial compared gabapentin with carbamazepine for the treatment of nerve-related pain in patients with Guillain-Barré syndrome who received plasma exchange.
- Trial name
- NCT07907406
- Testing
- Gabapentin, Carbamazepine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Lahore General Hospital
Migraine, Vestibular Migraine
Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma
Multiple sensory cues are typically generated by discrete events, and while they do not reach the cerebrum simultaneously, the brain can bind them temporally if they are interpreted as corresponding to a single event.
- Conditions
- Migraine, Vestibular Migraine, Vestibular Schwannoma, Motion Sickness
- Trial name
- NCT04196933
- Testing
- Temporal Binding Adaptation - PSS training, Temporal Binding Adaptation - PSS adaptation with VI stimulation, Chronic Motion-modulated Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Global Developmental Delay
Virtual Reality and Neuropsychiatric Rehabilitation in Patients With Global Developmental Delay.
Global Developmental Delay is a disorder characterized by failure achievement of expected milestones in different areas of psychomotor development before 5 years of age.
- Trial name
- NCT05879952
- Testing
- TAU + BTsN session, TAU
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Cerebral Oxygen Saturation, Postoperative Delirium
Association Between Local Cerebral Oxygenation Monitoring and Postoperative Delirium in Carotid Endarterectomy
Postoperative delirium (POD) is a common perioperative complication, which can lead to adverse outcomes. Patients undergoing carotid endarterectomy (CEA) were elderly, complicated with vascular risk factors, cognitive…
- Conditions
- Cerebral Oxygen Saturation, Postoperative Delirium, Carotid Endarterectomy
- Trial name
- NCT05198635
- Testing
- local cerebral oxygen saturation
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing Tiantan Hospital
Local Anaesthetic Drug Adverse Reaction
Computer - Controlled Intraligamentary Local Anaesthesia In Extraction of Primary Molars
Background: Exodontia poses a psychological threat for children, increasing the need for profound local anesthesia to assure painless extraction and maintain child cooperation on the dental chair.
- Trial name
- NCT04739735
- Testing
- Dental Local Anaesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Cerebral Palsy, Hemiplegia
The Effect of Combined Armeospring and CIT on Neuro-motor and Functional Recovery in Children With Unilateral CP
The purpose of this study is to assess the use of a commercially available arm weight supporting training system (Armeo®Spring) in conjunction with Constraint Induced Therapy (CIT) for improving upper extremity function for…
- Conditions
- Cerebral Palsy, Hemiplegia, Upper Extremity Weakness
- Trial name
- NCT02914925
- Testing
- ArmeoSpring/CIT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St Mary's Hospital for Children
Cervical Dystonia
CD-PROBE: Cervical Dystonia Patient Registry for the Observation of onabotulinumtoxinA Efficacy
This study is an observational trial which will measure the efficacy of onabotulinumtoxinA in treating Cervical Dystonia.
- Trial name
- NCT00836017
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 1,046 people
- Sponsor
- Allergan
Retinitis Pigmentosa, Usher Syndrome Type 2
Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene With Early to Moderate Vision Loss (Celeste)
The purpose of this study is to evaluate the efficacy safety and tolerability of QR-421a administered via intravitreal injection (IVT) in subjects with Retinitis Pigmentosa (RP) due to mutations in exon 13 of the USH2A gene with…
- Conditions
- Retinitis Pigmentosa, Usher Syndrome Type 2, Deaf Blind, Retinal Disease
- Trial name
- NCT05176717
- Testing
- QR-421a
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 5 people
- Sponsor
- Laboratoires Thea
Preterm Infant, Growth Acceleration
Effect on Early Somatic Growth of a Daily Kinesthetic Stimulation on Preterm Infants
Kangaroo position (KP), the essential component of the Kangaroo Mother Care (KMC) method, has been increasingly implemented, given the benefits of early skin-to-skin contact on the cerebral maturation of preterm infants.
- Conditions
- Preterm Infant, Growth Acceleration, Neurobehavioral Manifestations
- Trial name
- KISONKAP (NCT03574350)
- Testing
- KS in Kangaroo Position, KS in incubator
- Where
- Colombia
- Volunteers
- 66 people
- Sponsor
- Nathalie Charpak
Cerebral Palsy (CP), Hemiplegia and Hemiparesis
Aquatic Based Exercises Versus Mirror Therapy on Hand Dexterity and Strength in Hemiplegic Child
Cerebral palsy (CP) is a neurologic disorder that affects motor function, balance, and posture, and spastic hemiplegia is found in about one-third of persons with CP and often leads to devastating upper limb disability.
- Trial name
- NCT07072416
- Testing
- Aquatic Exercise, Mirror Therapy, Designed physical therapy program.
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alaa Noureldeen Kora
Complicated Appendicitis
Causes of Complicated Appendicitis at Referral Hospital
The study was conducted on a medical record of previously treated patients for acute appendicitis at HFSUH, Harar, Ethiopia. The study design was case-control with a total sample size of 402.
- Trial name
- AA (NCT05005104)
- Where
- Ethiopia
- Volunteers
- 402 people
- Sponsor
- Haramaya Unversity
Soft Tissue Injuries
Clinical Efficacy and Safety of Compound Methyl Salicylate Liniment
This clinical trial program was established according to the ethical principles of the Helsinki declaration and the GCP guiding principle, and a randomized grouping method was used to evaluate the efficacy and safety of Compound…
- Trial name
- NCT03362216
- Testing
- Compound Methyl Salicylate Liniment, Diclofenac Sodium Liniment
- Volunteers
- 216 people
- Sponsor
- Peking University People's Hospital
Seizures, Sleep
Pediatric Seizure Movement Bed Alarm
Nocturnal seizure and Sudden unexplained death in epilepsy patients (SUDEP) are major concerns for parents and creates anxiety and poor sleep conditions for many families dealing with epilepsy.
- Conditions
- Seizures, Sleep, Epilepsy
- Trial name
- PedsBedAlarm (NCT01855178)
- Testing
- Emfit Movement Monitor
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Le Bonheur Children's Hospital
Pain
Trial of an Oral Sucrose Solution Versus Placebo in Children 1 to 3 Months Old Needing Bladder Catheterization
INTRODUCTION AND JUSTIFICATION The use of sucrose has been well studied for certain procedures in neonatal intensive care unit patients and in the newborn nursery settings, particularly for venous blood draws, capillary blood…
- Trial name
- NCT01544985
- Testing
- 88% sucrose po solution
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Memory Replay, HippoCamera
A VIRTUAL Three-month Intervention Study of the Effects of a Smartphone Application (HippoCamera) on Memory in Teens and Young Adults With Down Syndrome
Down syndrome is a chromosomal abnormality associated with significant deficits across multiple cognitive domains, including a disproportionate deficit in hippocampally-dependent memory.
- Trial name
- NCT07008989
- Testing
- Memory replay
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston College
Prader-Willi Syndrome
Oxytocin Treatment in Neonates and Infants With Prader-Willi Syndrome
Prospective, randomized, placebo-controlled, double-blind part of the phase III trial to assess the safety and efficacy of 4 weeks oxytocin (OT) administration on oral and social skills in neonates/infants with Prader-Willi…
- Trial name
- OTBB3 (NCT04283578)
- Testing
- OT
- Where
- 7 sites in Belgium, France and 1 more
- Volunteers
- 52 people
- Sponsor
- University Hospital, Toulouse
Child Development Disorders, Preterm Infant
Reliability of Hammersmith Examination in Prediction of Neurological Outcomes (REHAPENO)
In this study workers are trying to test the correlation between Hammersmith Infant Neurological Examination and MRI brain/cranial ultrasound with early prediction of neurological developmental outcome of preterm neonates.
- Conditions
- Child Development Disorders, Preterm Infant, Cerebral Palsy
- Trial name
- REHAPENO (NCT03580252)
- Testing
- Correlation analyses for the outcomes
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Abha International Private Hospital
Mucopolysaccharidosis Type II (MPS II)
CAMPSIITE™ RGX-121 Gene Therapy in Subjects With MPS II (Hunter Syndrome)
RGX-121 is a gene therapy which is intended to deliver a functional copy of the iduronate-2-sulfatase gene (IDS) to the central nervous system.
- Trial name
- NCT03566043
- Testing
- RGX-121
- Where
- 5 sites in United States, Brazil
- Volunteers
- 48 people
- Sponsor
- REGENXBIO Inc.
Post-Traumatic Seizure Disorder, Head Injuries
Phase III Double Blind Trial of Valproate Sodium for Prophylaxis of Post Traumatic Seizures
OBJECTIVES: I. Determine whether treating head injured patients with valproate sodium will reduce the risk of developing seizures as a result of the head injury. II.
- Trial name
- NCT00004817
- Testing
- phenytoin, valproate sodium
- Volunteers
- 385 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
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