Clinical trials: Neurological Condition
ALS, Autism Spectrum Disorder
Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products
This is an observational study of medical marijuana manufactured and dispensed by Ilera and given as standard treatment for a variety of approved serious medical conditions as defined by individual state law.
- Conditions
- ALS, Autism Spectrum Disorder, Cancer, Spasticity, Muscle
- Trial name
- Ilera (NCT03886753)
- Testing
- Registry, PK microsampling of blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Neuropathy, Phantom Limb Pain
Immersive Virtual Reality for Neuropathic Pain
Investigating how neuropathic limb pain, including phantom limb pain or complex regional pain syndrome, is affected by virtual reality.
- Conditions
- Neuropathy, Phantom Limb Pain, Complex Regional Pain Syndromes, Neuropathic Pain
- Trial name
- NCT03203772
- Testing
- Immersive Virtual Reality
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Loma Linda University
Kinky Hair Syndrome
Copper Histidine Therapy for Menkes Diseases
Menkes Disease is a genetic disorder affecting the metabolism of copper. Patient with this disease are both physically and mentally retarded. Menkes disease is usually first detected in the first 2-3 months of life.
- Trial name
- NCT00001262
- Testing
- Copper Histidine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebral Palsy, Hemiparesis; Poststroke/CVA
Characterization of Muscle Activity During a Surface EMG-controlled Rehabilitation Game
The aim of this pilot study is to evaluate muscular activity during a single session of surface electromyography controlled exergame (muscle activation, number of contraction…) in cerebral palsy kids, hemiparetic adults and…
- Conditions
- Cerebral Palsy, Hemiparesis; Poststroke/CVA, Healthy (Controls)
- Trial name
- CONTRACTIV-1S (NCT07838688)
- Testing
- Surface electromyography (sEMG)-controlled rehabilitation game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Cornelia De Lange Syndrome
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment
The study "Cornelia de Lange Syndrome: assessing positive effects of Lithium treatment - CLoSER" aims to evaluate the effectiveness on behavioral modifications of lithium carbonate therapy in patients with Cornelia de Lange…
- Trial name
- CLoSER (NCT06789783)
- Testing
- Lithium Carbonate Capsule
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- University of Milan
Wolfram Syndrome 1, Optic Atrophies, Hereditary
Does Recessive Optic Atrophy Due to WFS1 Exist?
All patients with Wolfram syndrome and recessive optic atrophy due to a mutation of the WFS1 from a single Center were included in a retrospective study.
- Trial name
- NCT07336966
- Testing
- analyse study
- Volunteers
- 45 people
- Sponsor
- Hôpital Necker-Enfants Malades
Rett Syndrome
The Rett Syndrome Global Registry
The Rett Global Registry is a fully remote, global, caregiver-reported registry to collect information about caring for a loved one with Rett syndrome.
- Trial name
- NCT04900493
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Rett Syndrome Research Trust
Developmental Disability
Communication Outcomes for South African Children With Developmental Disabilities
The goal is to remediate speech and language disorders early in the lives of South African children with significant developmental disorders (DD) by enhancing the health care service delivery system to better serve families…
- Trial name
- NCT03409406
- Testing
- Caregiver Intervention, ST Intervention
- Where
- South Africa
- Volunteers
- 100 people
- Sponsor
- Georgia State University
Cervical Spondylosis, Wind-Cold Syndrome
Efficacy of Three-Needle Dazhui and Electroacupuncture for Cervical Spondylosis With Wind-Cold Syndrome
Cervical spondylosis is a prevalent health issue that significantly impacts quality of life, with Cervical Spondylotic Radiculopathy (CSR) accounting for 60-70% of cases While modern medicine offers various treatments, the…
- Conditions
- Cervical Spondylosis, Wind-Cold Syndrome, Neck Pain, Cervical Spondylotic Radiculopathy
- Trial name
- NCT07640126
- Testing
- Standard Electroacupuncture, Three-Needle Dazhui Technique & Electroacupuncture, Standard Care Drugs
- Where
- Vietnam
- Volunteers
- 74 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients
Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients
This is a pilot feasibility study examining the use of immersive virtual reality (VR) in adult intensive care unit (ICU) patients.
- Conditions
- Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients, Agitation Associated With Critical Illness, Anxiety Acute
- Trial name
- NCT07649876
- Testing
- Virtual reality (VR) therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Communication, Pain
Visualizations to Improve Pain Communication Between Patients, Interpreters, and Providers
The purpose of this study is to pilot test a pain assessment information visualization (InfoViz) tool to facilitate communication about pain severity, location, and quality to increase mutual understanding between patients with…
- Trial name
- NCT04975789
- Testing
- InfoViz
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- University of Wisconsin, Madison
Spastic Cerebral Palsy
Short Term Follow-up of a Botulinum Toxin Intervention in Children With Spastic Cerebral Palsy
This study investigates the effect of integrated Botulinum Neurotoxin A (BoNT) treatment on morphologic muscle and tendon properties, spasticity, joint stiffness, joint range of motion, muscle strength, gait and gross motor…
- Trial name
- NCT05126693
- Testing
- Botulinum Toxin treatment combined with a post-BoNT intensive physical therapy period guided by individualized treatment goals.
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Low Back Pain
Lumbar Manipulation and Exercise for the Treatment of Acute Low Back Pain in Adolescents
The purpose of this study is to determine if the addition of lumbar manipulation will improve function, decrease pain, and recurrence in adolescents with low back pain.
- Trial name
- NCT02111278
- Testing
- Lumbar Manipulation, Physical Therapy
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- Nationwide Children's Hospital
Cerebral Palsy
Effect of Botulinum Toxin on Muscles of Children With Cerebral Palsy
Cerebral palsy (CP) is a group of non-progressive motor dysfunction but often changing, secondary to injury or brain abnormalities that occur in early stages of development.
- Trial name
- TOXIMUS_CP (NCT02853240)
- Testing
- Muscle biopsy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Homonymous Hemianopia
Clinical Trial of Multi-Periscopic Prism Glasses for Hemianopia
This clinical trial will evaluate the efficacy of two types of high-power prism glasses that provide field of view expansion for patients with homonymous hemianopia (the complete loss of half the field of vision on the same side…
- Trial name
- NCT04827147
- Testing
- Multi-Periscopic Prism (MPP) glasses, Fresnel Peripheral Prism (FPP) glasses
- Where
- 8 sites in United States
- Volunteers
- 64 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Postprocedural Gastric Stasis
Gastric Emptying After Infracolic or Supracolic Gastrojejunostomy Following Pancreaticoduodenectomy
Patients undergoing whipples pancreaticoduodenectomy tend to develop delayed gastric emptying. The study compares two types of anastamosis of stomach to jejunum (supracolic and infracolic) and compares whether it influences the…
- Trial name
- NCT01191138
- Testing
- Infracolic gastrojejunal anastamosis, Supracolic gastrojejunal anastamosis
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Asian Institute of Gastroenterology, India
Loss of Visual Contrast Sensitivity, Near Vision
Visual Performance Following Implantation of Presbyopia Correcting IOLs
The purpose of the current study was to compare the visual performance after bilateral implantation of the Panoptix IOL , or the AT LISA IOL or Tecnis Symfony IOL .
- Conditions
- Loss of Visual Contrast Sensitivity, Near Vision, Visual Impairment
- Trial name
- NCT04907955
- Testing
- phacoemulsification with implantation of presbyopia correcting IOL
- Where
- Kuwait
- Volunteers
- 50 people
- Sponsor
- Dar Al Shifa Hospital
Augmented Reality
The Effect of an Augmented Reality Game on Pain, Fear, and Care Satisfaction Levels During Allergy Testing in Children Aged 4-12 Years
The aim of this study is to examine the effects of augmented reality (AR) games on pain, fear, and care satisfaction, and to contribute to the literature on innovative interventions that enhance the healthcare experiences of…
- Trial name
- NCT06986655
- Testing
- Augmented Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Koç University
Asthma Attack, Asthma in Children
The Effect of Nebulization Positions in Asthmatic Children
The purpose of this study was to establish the effect on pulse rate, oxygen saturation, respiratory rate, pain and anxiety levels of Fowler's and the forward-leaning positions during nebulization in children experiencing asthma…
- Conditions
- Asthma Attack, Asthma in Children, Asthma Acute, Asthma
- Trial name
- NCT05318885
- Testing
- A Randomized Controlled Study
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Istanbul University - Cerrahpasa
Mucopolysaccharidosis Type I (MPS I), Mucopolysaccharidosis Type II (MPS II)
Lysosomal Storage Disease: Health, Development, and Functional Outcome Surveillance in Preschool Children
Hypothesis: Children diagnosed with a lysosomal disease will exhibit developmental, adaptive, and behavioral strengths and difficulties depending upon 1) biomedical risk factors (i.e.
- Conditions
- Mucopolysaccharidosis Type I (MPS I), Mucopolysaccharidosis Type II (MPS II), Mucopolysaccharidosis Type III (MPS III), Mucopolysaccharidosis Type VI (MPS VI)
- Trial name
- NCT01938014
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Chicago
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