Clinical trials: Neurological Condition
Suicidal Ideation, Suicidal
Reward Sensitivity Digital Intervention for Suicide Risk
The goal of this clinical trial is to develop and test an app designed to reduce suicide risk and improve emotional well-being in adolescents.
- Conditions
- Suicidal Ideation, Suicidal, Suicidal Thoughts, Digital Health Intervention
- Trial name
- DIGIReward (NCT07661901)
- Testing
- Suicide prevention treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Deafness
Comparison of the Bilateral Sequential and Simultaneous Cochlear Implantation in the Deaf Children
In France the indication of bilateral cochlear implant (CI) is limited to specific cases. The impact on perception and language of bilateral CI simultaneous versus sequential has to be established before discussing the…
- Trial name
- Cochleo (NCT01499901)
- Testing
- bilateral cochlear Implantation in sequential, bilateral cochlear Implantation in simultaneous
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neuro-Ophthalmology
Safety and Normative Data With Neos™
The goal of this clinical study is to collect standard data for the medical device neos™. neos™ is a system that shows images and measures the resulting eye movements and pupil size. Collecting standard data involves three steps.
- Trial name
- neos-SNOW (NCT07258212)
- Where
- 3 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- machineMD AG
Pain, Stress, Physiological
The Effect of a Musical Intervention on Stress Response to Venepuncture
Randomised Crossover Trial in Preterm Infants less than 32 weeks to assess Music therapy and sucrose versus sucrose on stress
- Trial name
- NCT03028844
- Testing
- Music therapy
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- University College Cork
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pain, Postoperative, Excavatum, Pectus
Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery
This will be a prospective observational study to determine the association between specific genotypes, epigenetics, behavioral, social and biological factors, with the phenotypes, defined by pain perception, postoperative pain…
- Conditions
- Pain, Postoperative, Excavatum, Pectus, Scoliosis Idiopathic
- Trial name
- NCT04031716
- Testing
- Meditation
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Influenza, Human, Arthralgia
An Intravenous (IV) Zanamivir Pharmacokinetics (PK) Study in Hospitalized Neonates and Infants With Influenza Infection
Influenza infection is an important public health priority, with seasonal outbreaks and pandemics causing considerable global morbidity and mortality.
- Trial name
- NCT04494412
- Testing
- Zanamivir
- Where
- 6 sites in Italy, Poland and 1 more
- Volunteers
- 8 people
- Sponsor
- GlaxoSmithKline
Pain Score
Prevention of Pain Caused by the Oro-gastric Tube Laying in Neonatology
Subject of research : Evaluation of a technique of care to reduce the pain caused by the laying of the gastric tube in the newborn
- Trial name
- DOLATSONG (NCT03142230)
- Testing
- the laying of the gastric tube and a group using the holed baby bottle nipple, the feeding tube ideally positioned at the center of the intersection pharyngeal, the laying of the gastric tube and a group with simple non-nutritive suction, the feeding tube passing next to the newborn's personal pacifier
- Where
- 3 sites in France
- Volunteers
- 71 people
- Sponsor
- Centre Hospitalier Sud Francilien
Delirium, Pediatric Disorder
Emergence Delirium in Children for Magnetic Resonance Imaging
Sedation or anaesthesia is necessary to be able to perform magnetic resonance imaging (MRI) on children who cannot keep still or are uncooperative, and thus the targets of maximum patient safety, successful imaging, and the…
- Conditions
- Delirium, Pediatric Disorder, Anesthesia
- Trial name
- NCT04816344
- Testing
- Outpatient Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Turkiye Yuksek Ihtisas Education and Research Hospital
Cerebral Palsy, Chronic Post Surgical Pain
Chronic Postsurgical Pain
The study purpose is to document the typical trajectory of perioperative pain experience in Cerebral Palsy (CP) and to identify important predictive factors for the development of chronic postsurgical pain.
- Trial name
- CPSP (NCT05764681)
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Chantel Burkitt
Autism Spectrum Disorder, Fra(X) Syndrome
Establishing a Diagnostic and Therapeutic Index in Autism Spectrum Disorder (ASD) and Fragile X Syndrome
The purpose of this study is to accumulate and quantitatively analyze data on the microbiome, serotonin signaling and genetics, and inflammatory cytokines from patients with Autism Spectrum Disorder and Fragile X Syndrome.
- Trial name
- NCT04869930
- Testing
- specimen collection
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nova Mentis Life Science Corp
Autism Spectrum Disorder, Developmental Delay
MAP Autism Prediction Study
This pilot clinical trial tests the hypothesis that certain blood metabolite levels can be used to predict Autism Spectrum Disorder (ASD).
- Trial name
- MAP (NCT04672967)
- Testing
- BioROSA MAP test
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- BioROSA Technologies Inc
Pain
An Effectiveness and Safety Study of Acetaminophen 1000 mg and Ibuprofen 400 mg in Postoperative Dental Pain
The purpose of this study is to determine the onset of pain relief from a single dose of acetaminophen and ibuprofen in subjects experiencing postoperative dental pain following the surgical extraction of at least three molars.
- Trial name
- NCT00240864
- Testing
- acetaminophen, ibuprofen
- Volunteers
- 224 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Hearing Loss
The Hearing Aid Effectiveness After Aural Rehabilitation (HEAR) Trial
This study compares the effectiveness of hearing aid appointments provided in a group format to those provided in an individual format.
- Trial name
- NCT00260663
- Testing
- Group hearing aid fittings, Group hearing aid follow-up
- Where
- United States
- Volunteers
- 660 people
- Sponsor
- US Department of Veterans Affairs
Dystonia
Theta-burst Transcranial Magnetic Stimulation
Theta-burst transcranial magnetic stimulation (TBS) is a type of repetitive transcranial magnetic stimulation (rTMS) method that reduces the excitability of a small region of brain for less than one hour.
- Trial name
- NCT00878787
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Southern California
Sickle Cell Disease, Vaso-occlusive Crisis
Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease
Acute vaso-occlusive crisis (VOC) is the most common complication in patients with sickle cell disease (SCD) and pain related to VOC is often inadequately treated.
- Trial name
- NCT03353584
- Testing
- Virtual Reality Therapy
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- St. Jude Children's Research Hospital
Horner's Syndrome
Clinical Efficacy of Supraclavicular Block for Arthroscopic Shoulder Surgery
The aim of this study is to compare the efficacy of supraclavicular and interscalene brachial plexus blocks in the patients undergoing arthroscopic shoulder surgery.
- Trial name
- NCT01958801
- Testing
- Supraclavicular block, Interscalene block
- Where
- South Korea
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Daegu Catholic University Medical Center
Traumatic Brain Injury (TBI)
Efficacy and Neural Basis of Music-based Neurological Rehabilitation for Traumatic Brain Injury
Traumatic brain injury (TBI) is one of the leading causes of serious, life-long disability among adolescents and young adults. Especially the cognitive, emotional, and motors deficits caused by TBI often impair everyday…
- Trial name
- MUBI (NCT01956136)
- Testing
- Music-based Neurological Rehabilitation (MBNR), Standard Care (SC)
- Where
- 3 sites in Finland
- Volunteers
- 40 people
- Sponsor
- University of Helsinki
Pain, Breastfeeding
Non-pharmacological Analgesia During Heel Prick
Objective To investigate the analgesic effect (measured with NIPS) of breastfeeding in addition to skin-to-skin contact versus other methods of non-pharmacological analgesia during blood sampling through heel lance in healthy…
- Trial name
- NCT01576432
- Testing
- Assess pain with the NIPS score
- Where
- Spain
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Acute Coronary Syndrome
Secondary Prevention in Acute Coronary Syndromes: A CALIBER Study
All contemporary guidelines for secondary prevention in acute coronary syndromes recommend a combination of aspirin, beta-blockers, ACE-inhibitors and statins. Yet underutilisation of these drugs is common.
- Trial name
- NCT01162187
- Volunteers
- 400,000 people
- Sponsor
- University College, London
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