Clinical trials: Neurological Manifestations
Congenital Heart Defect, Chronic Pain
Impacting Children's Physical and Mental Health Through Kinesiology Support in Clinical Care
Over the past four decades, it has become clear that childhood physical activity carries with it a myriad of beneficial effects.
- Conditions
- Congenital Heart Defect, Chronic Pain, Concussion Post Syndrome, Cerebral Palsy
- Trial name
- NCT04106154
- Testing
- Kinesiology Support
- Where
- Canada
- Volunteers
- 111 people
- Sponsor
- Children's Hospital of Eastern Ontario
Dyslexia
Dyslexia, Motor Control and Proprioception
The investigators hypothesize that children with dyslexia present proprioceptive disorders and the purpose of the present study is to better understand relationships between motor control, proprioception and academic learnings.
- Trial name
- NCT03364010
- Testing
- Evaluation of proprioception, Evaluation of motor learning, Evaluation of written language
- Where
- France
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Phantom Limb Pain
Comparison of Efficacy of Mirror Therapy vs Mental Imagery in Reduction of Phantom Limb Pain in AKAP
Limb amputation results in many types of pain, including localized pain at the stump and projected pain experienced by the patient in the location where the amputated limb used to be, known as phantom limb pain (PLP).
- Trial name
- NCT06428123
- Testing
- Mirror Therapy on present Lower Limb, Mental Imagery on present Lower Limb
- Where
- 2 sites in Pakistan
- Volunteers
- 24 people
- Sponsor
- Superior University
Stuttering, Stuttering, Adult
Exploring the Nature, Assessment and Treatment of Stuttering
The purposes of this study are to 1) investigate potential speech, language, and psychosocial contributions to the experience of stuttering in monolingual and multilingual speakers, and to 2) evaluate interdisciplinary…
- Conditions
- Stuttering, Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
- Trial name
- NCT05908123
- Testing
- The Blank Center CARE Model(TM) for Individuals who Stutter
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Labor Pain
Analgesic Efficacy and Obstetric Effects of Tramadol, Paracetamol and Placebo in Active Labor
This randomized, double-blind, placebo-controlled trial aims to compare the analgesic efficacy and obstetric effects of tramadol (100 mg IV) versus paracetamol (1 g IV) versus placebo (saline solution) in nulliparous women during…
- Trial name
- TRAMPA (NCT07440069)
- Testing
- Tramadol Hydrochloride, Paracetamol (acetaminophen)
- Where
- 2 sites in Honduras
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Ataxia
Special Drug Use Investigation for Arixtra® (Fondaparinux) Venous Thromboembolism Treatment
The purpose of this post-marketing surveillance study is to collect and assess information on safety and efficacy of fondaparinux injection in patients with venous thromboembolism (VTE).
- Trial name
- NCT01428531
- Testing
- Fondaparinux Sodium
- Volunteers
- 200 people
- Sponsor
- GlaxoSmithKline
Sickle Cell Disease, Chronic Pain
Use of a Mobile-based App for SCD Patients
The study will seek to enroll 100 sickle cell or thalassemia patients who are age 12 or older who have access to a smartphone or tablet with Internet access daily.
- Trial name
- SMART (NCT01833702)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Duke University
Anesthesia, Pain
Pupillometry Guided Remifentanil Administration In Pediatric Anesthesia
The aim of this prospective randomized study is to evaluate the impact of peroperative pupillometry monitoring on per and post-operative opioid consumption in pediatric anesthesia.
- Conditions
- Anesthesia, Pain, Child
- Trial name
- NCT02683837
- Testing
- Remifentanil, Pupillometry, Sevoflurane
- Where
- Switzerland
- Sponsor
- University Hospital, Geneva
Stammering
Effects of Tele Speech Therapy on the Treatment of Stammering in Adults Who Stutter
The aim of the study is to determine the effectiveness of telespeech therapy on the treatment of stammering.
- Trial name
- NCT06937437
- Testing
- Teletherapy, Traditionally speech therapy
- Where
- Pakistan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Postoperative Pain
Percutaneous Peristyloid Glossopharyngeal Block After Tonsillectomy
Adenotonsillectomy surgery in paediatrics is commonly managed as an ambulatory surgery. This may be attributed to the use of the electro-dissection surgical technique that decreases the incidence of immediate postoperative…
- Trial name
- NCT04970680
- Testing
- glossopharyngeal nerve block
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Suez Canal University
Diplegic Cerebral Palsy
"Immediate Effect of DAFO on Gross Motor Function and Balance in Diplegic Cerebral Palsy
" Study will investigate the immediate effect of DAFO usage on balance and gross motor functions in individuals with spastic diplegic cerebral palsy.
- Trial name
- NCT06343688
- Testing
- "Assessment of Balance and Lower Extremity Gross Motor Function with and without DAFO"
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Ocular Motility Disorder
Evaluation and Treatment of Pediatric Eye Diseases
This study offers evaluation and treatment for patients with pediatric eye diseases, particularly amblyopia and strabismus. The protocol is not designed to test new treatments; rather, patients will receive current standard of…
- Trial name
- NCT00006422
- Testing
- current standard of care treatments
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Eye Institute (NEI)
Pain
Assessing the Efficacy of Virtual Reality Analgesia (VRA) in Pediatric Patients for Pain Control
To evaluate the efficacy of virtual reality analgesia (VRA) for pediatric patients undergoing Botulinum toxin injections (BTI) for spasticity management.
- Trial name
- PEDSPAINVR (NCT03480724)
- Testing
- Google Cardboard VRA, Oculus Rift VRA
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Montefiore Medical Center
Chronic Pain, Acute Pain
Building a Swiss Pain Registry: A National Framework for Acute and Chronic Pain Assessment
The goal of this observational registry is to systematically collect and analyse real-world clinical and patient-reported data in individuals receiving treatment for acute and chronic pain.
- Trial name
- NCT07717762
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Epileptic Seizure
A Clinical Study of Epilepsy Localization and Prognosis Based on PET and Resting-state fMRI
1. By following up the prognosis of surgical patients, the application value of Cortex ID quantitative analysis in the localization of epilepsy foci was studied. 2.
- Trial name
- NCT05567042
- Testing
- No intervention
- Volunteers
- 50 people
- Sponsor
- Li Shuangshuang
Pain, Preterm Newborn
Evaluation of Pain in Preterm Newborn
The purpose of this study is to correlate the composite PIPP-R (Premature Infant Pain Profile-Revised) scale and the parasympathetic nervous system (heart rate variability).
- Trial name
- TRIPAIN (NCT02885051)
- Testing
- Recording of skin conductance and heart rate variability.
- Where
- France
- Volunteers
- 91 people
- Sponsor
- University Hospital, Brest
Pain Relief
Buzzy Distraction During Venipuncture
Venipuncture is one of the most common iatrogenic painful and stressful procedures performed on children. Interventions aimed at reducing the distress related to this experience are widely and strongly recommended.
- Trial name
- NCT02969902
- Testing
- Buzzy® device, Hand-held computer
- Volunteers
- 200 people
- Sponsor
- IRCCS Burlo Garofolo
Refractory Epilepsy, Focal Seizure
Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
This is a multiple site, randomized, double blinded parallel-group controlled study. The purpose of this study is to evaluate efficacy, safety, and tolerability of repeated, daily sessions with the STARSTIM device, which delivers…
- Conditions
- Refractory Epilepsy, Focal Seizure, Seizures, Focal, Seizures
- Trial name
- NCT04770337
- Testing
- STARSTIM device
- Where
- 32 sites in United States, Belgium and 2 more
- Volunteers
- 127 people
- Sponsor
- Neuroelectrics Corporation
Trauma, Pain
Intranasal Fentanyl for Pain Management
Goal of the research will be to demonstrate a reduction in reported pain following the atomization and intra-nasal administration of Fentanyl versus the reduction in pain achieved from intravenous Fentanyl.
- Trial name
- NCT00882960
- Testing
- intravenous fentanyl, intra-nasal fentanyl
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Genesys
Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder
Adverse Effect of Prolonged Methylphenidate Treatment on Cardiac Functions
The purpose of this study is to find out whether prolonged treatment with methylphenidate has any adverse effect on cardiac functions and measurements.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder, Attention Deficit Disorders With Hyperactivity
- Trial name
- NCT00372359
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Ornit Cohen
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