Clinical trials: Neurology
Cognitive Function 1, Social, Mental Health Wellness 1
Effects of an Exercise Program on Cognition and Brain in Overweight/Obese Preadolescent Children
The ActiveBrains project aims to examine whether a 5-months physical exercise program has benefits on cognition and brain, as well as on selected physical and mental health outcomes in preadolescent overweight/obese children.
- Conditions
- Cognitive Function 1, Social, Mental Health Wellness 1, Obesity, Overweight
- Trial name
- ActiveBrains (NCT02295072)
- Testing
- A 5-months physical exercise-based program
- Volunteers
- 110 people
- Sponsor
- Universidad de Granada
Rolandic Epilepsy
Music Perception in SeLECTs
Self-limited epilepsy with centrotemporal spikes (SeLECTS) is the most frequent epilepsy syndrome in children between the ages of 4 and 13 years.
- Trial name
- EpiMUS (NCT06545708)
- Testing
- Patients
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Epilepsy
Bridging the Childhood Epilepsy Treatment Gap in Africa
About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs).
- Trial name
- BRIDGE (NCT04290975)
- Testing
- Task-shifting epilepsy care to epilepsy-trained community health workers (CHWs), Enhanced usual care for epilepsy (EUC)
- Where
- 3 sites in Nigeria
- Volunteers
- 1,672 people
- Sponsor
- Vanderbilt University Medical Center
Status Epilepticus, Non-Convulsive Status Epilepticus
Point-of-care EEG in the Pediatric Emergency Department
The researchers investigate the use of a simplified electroencephalogram (point-of-care EEG) in the pediatric emergency department for children with impaired consciousness or an ongoing epileptic seizure ("status epilepticus").
- Conditions
- Status Epilepticus, Non-Convulsive Status Epilepticus, Altered Mental Status
- Trial name
- NCT05418634
- Testing
- point of care EEG
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Children's Hospital, Zurich
Acute Disseminated Encephalomyelitis
Management Of Acute Disseminating Encephalomyelitis
Acute disseminated encephalomyelitis is an immune-mediated inflammatory demyelinating disease of the central nervous system, which is typically transitory and self-limiting.
- Trial name
- NCT03284801
- Testing
- management of acute disseminating encephalomyelitis
- Volunteers
- 40 people
- Sponsor
- Assiut University
CTX - Cerebrotendinous Xanthomatosis
An Observational Study for Evaluation of for the Prevalence of Cerebrotendinous Xanthomatosis (CTX) Disease
The prevalence of CTX in our country is estimated to be 1 / 50.000. The aim of this study is to screen more volunteers by conducting a larger screening from neurology and pediatric metabolism clinics in Turkey.
- Trial name
- GEN-EYE-II (NCT04113083)
- Testing
- Blood sampling for cholestanol analysis
- Where
- 22 sites in Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- TRPHARM
Cardiovascular Diseases, Endocrinology
BEhavioral and Adherence Model for Improving Quality, Health Outcomes and Cost-Effectiveness of healthcaRe
Lack of adherence to treatment is a widespread issue worldwide, which leads to higher healthcare utilisation rates and even premature death.
- Conditions
- Cardiovascular Diseases, Endocrinology, Inmunology, Neurology
- Trial name
- BEAMER (NCT06856902)
- Testing
- B-COMPASS implementation
- Where
- 10 sites in Germany, Italy and 6 more
- Volunteers
- 6,190 people
- Sponsor
- Technical University of Madrid
Neurology, Newborn
SWC on aEEG in Post-surgical Neonates on Morphine and Midazolam
Objectives: Sleep characteristics have been used for prediction of neuro-developmental outcome. The aim of our study was to evaluate the influence of morphine and midazolam on the development of SWC in newborns > 32 weeks'…
- Conditions
- Neurology, Newborn, Analgesia, Sedation
- Trial name
- NCT01212419
- Volunteers
- 47 people
- Sponsor
- Royal Children's Hospital
Glioblastoma Multiforme
Dendritic Cell Cancer Vaccine for High-grade Glioma
A randomised, open-label, 2-arm, multi-centre, phase II clinical study with one group receiving standard therapy with Temozolomide, radiotherapy, and Trivax; and a control group receiving standard therapy with Temozolomide and…
- Trial name
- GBM-Vax (NCT01213407)
- Testing
- Trivax, Temozolomide, Surgery, Radiotherapy, Temozolomide, Surgery, Radiotherapy
- Where
- 8 sites in Austria
- Volunteers
- 87 people
- Sponsor
- Activartis Biotech
Apheresis Related Complication
Efficacy and Tolerance of Therapeutic Apheresis in Paediatric Neurology: a French Multicenter Study
After developing in pediatric hematology and nephrology, therapeutic apheresis is increasingly used in pediatric neurology despite a sparse level of evidence.
- Trial name
- NCT04845516
- Testing
- Efficacy of apheresis
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier