Clinical trials: Neuron Specific Enolase
Congenital Heart Disease (CHD), Hypoxic Encephalopathy
Early Detection of Brain Injury After Congenital Heart Surgery in Infants
Infants with congenital heart disease undergoing cardiac surgery with extracorporeal circulation are at risk for perioperative hypoxic-ischaemic brain injury.
- Trial name
- NCT07424976
- Testing
- Observational study: blood analisys, EEG, MRI
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Consciousness Disorders, Persistent Vegetative State
Multimodal Assessment and Prognosis in Disorders of Consciousness After Severe Brain Injury (CyDoC-MAP)
After a severe brain injury some patients survive but cannot communicate, and deciding early which of them are likely to recover consciousness remains one of the hardest problems in neurocritical care.
- Conditions
- Consciousness Disorders, Persistent Vegetative State, Unresponsive Wakefulness Syndrome, Minimally Conscious State
- Trial name
- CyDoC-MAP (NCT07736820)
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- Nicosia General Hospital
Spinal Cord Injury
S-100B and Neuron-specific Enolase (NSE) in Spinal Trauma
The investigators are studying the clinical worth of the serum markers S-100B and NSE in patients with spinal cord injuries e.g. in patients with vertebral fractures.
- Trial name
- WBS (NCT00980434)
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Craniosynostosis, Anesthesia
Influence of General Anesthesia on the Dynamic Changes in Brain Damage Markers During and After Craniosynostosis Operations in Infancy
The issue of anesthetics neurotoxicity is one of the most discussed topics in pediatric anesthesiology, thus it opens the question of the safety of commonly used anesthetics in the pediatric patient.
- Trial name
- TAnBrainDam (NCT05911139)
- Where
- Slovakia
- Volunteers
- 45 people
- Sponsor
- Comenius University
Cardiac Surgery, Postoperative Cognitive Dysfunction
The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery
To assess the impact of Dexmedetomidine on postoperative cognitive function and serum Neuron Specific Enolase levels as an indicator of neuronal injury in patients undergoing open heart surgery
- Conditions
- Cardiac Surgery, Postoperative Cognitive Dysfunction, Neurologic Manifestations
- Trial name
- NCT06655025
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sohag University
Peri-operative Injury, Newborn, Infant, Disease
Cerebral Oxymetry and Neuronal Markers in Newborns and Infants Undergoing Surgery
The purpose of this study is to assess whether peri-operative period in neonates and infants is associated with an increase in blood biomarkers, specific for neuronal injury, and to correlate them with clinical variables and…
- Trial name
- NEMARKO (NCT02423369)
- Testing
- Cerebral near infrared spectroscopy, S-100B protein in serum, NSE protein in serum
- Where
- Lithuania
- Volunteers
- 49 people
- Sponsor
- Lithuanian University of Health Sciences