Clinical trials: Neurosurgical Procedures
Infant Conditions
Comparison of Different Video Laryngoscopes in Infants Undergoing Neurosurgery: a Prospective Randomized Clinical Trial
difficult intubation is high in the 0-1 year period. Video laryngoscopes improved intubation success rate when compared to direct laryngoscopy.
- Trial name
- NCT04153370
- Testing
- Airtraq, glidescope, c-mac
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Craniopharyngioma, Obesity
Prospective Study of Children and Adolescents With Craniopharyngioma
The present investigation is a prospective, multicenter study evaluating craniopharyngioma patients' prognoses following the various currently-practiced therapeutic strategies.Primary goals of the study are to establish quality…
- Trial name
- NCT01272622
- Testing
- Radiation, wait and watch
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Klinikum Oldenburg gGmbH
Surgery
TetraGraph in Rocuronium Infusions
This is a prospective, non-blinded study to evaluate rocuronium infusion requirements using the TetraGraph Neuromuscular Transmission Monitor during surgical procedures in patients less than 18 yrs. of age.
- Trial name
- NCT06472284
- Testing
- TetraGraph
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Joseph D. Tobias
Primary Brain Tumor
Laser Ablation in Stereotactic Neurosurgery (LAISE): NeuroBlate® Retrospective Registry
The NeuroBlate® System (NBS), is a minimally invasive robotic laser thermotherapy tool. It employs a pulsed surgical laser to deliver targeted energy to abnormal brain tissue caused by tumors and lesions.
- Trial name
- NCT02389855
- Testing
- NeuroBlate® System Therapy
- Where
- 9 sites in United States
- Volunteers
- 144 people
- Sponsor
- Monteris Medical
Dream Content
The Impact of Epilepsy Surgery on Dream Content
Prospective observational study on epilepsy patients undergoing partial brain resection surgery (i.e. anterior temporal lobectomy) to assess the change in dream content before and 3 months and 1 year after surgery using…
- Trial name
- NCT02731443
- Testing
- Epilepsy surgery, Depth electrodes insertion
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre
Hydrocephalus, Ventriculoperitoneal Shunt Infection
Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different Etiologies
Objectives Primary: To measure the reduction in VP shunt infection rates using topical vancomycin powder. Secondary: To compare efficacy across different Etiological Strata (Congenital, Post-hemorrhagic, post-inflammatory).
- Conditions
- Hydrocephalus, Ventriculoperitoneal Shunt Infection, Surgical Site Infection (SSI), Cerebrospinal Fluid Shunt Infection
- Trial name
- NCT07547826
- Testing
- Topical Vancomycin Powder, Standard Perioperative Care
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Assiut University
Post Craniotomy Surgery, Cancer
The Management of Postoperative Craniotomy Pain in Pediatric Patients
The purpose of this prospective, clinical observational trial is to assess the incidence of pain (and analgesia), methods of pain assessment (and by whom), prescribed analgesics, methods of analgesic delivery, and patient/parent…
- Conditions
- Post Craniotomy Surgery, Cancer, Epilepsy, Vascular Malformations
- Trial name
- NCT01576601
- Where
- 3 sites in United States
- Volunteers
- 81 people
- Sponsor
- Johns Hopkins University
Brain Tumor
Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures
The objective of the study is to assess safety of panitumumab-IRDye800 in pediatric patients undergoing brain surgery to remove suspected tumors.
- Trial name
- NCT04085887
- Testing
- Panitumumab-IRDye800, Pinpoint-IR9000 endoscopic/handheld device, Explorer Air camera
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
CSF Leak
The Paediatric EVICEL® Neuro Study
The purpose of this study is to evaluate the safety and efficacy of EVICEL® when used for suture-line sealing in dura-mater closure in elective or urgent paediatric cranial neurosurgery to provide intraoperative watertight…
- Trial name
- NCT02309645
- Testing
- EVICEL® Fibrin Sealant, Sutures Only
- Where
- 7 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- Ethicon, Inc.
Hypothermia
Preventing Inadvertent Hypothermia in Paediatric Neurosurgery in Malawi
The investigators wish to undertake a randomized controlled non-inferiority trial to evaluate the ability of a simple and low-cost method (Hibler´s method of wrapping the patient in multiple insulating layers) to prevent…
- Trial name
- NCT02975817
- Testing
- Hibler's, Warm Air
- Where
- Malawi
- Volunteers
- 76 people
- Sponsor
- Oslo University Hospital
Hypothermia Following Anesthesia, Neurosurgery
Preventing Inadvertent Hypothermia in Patients Undergoing Major Spinal Surgery
Background Major spinal surgery tend to be lengthy with an increased risk of hypothermia. A quality improvement project of patients undergoing major spinal surgery showed that 67 % were hypothermic at the beginning of surgery.
- Conditions
- Hypothermia Following Anesthesia, Neurosurgery, Scoliosis, Kyphosis
- Trial name
- NCT03193905
- Testing
- Bairhugger Full Access Underbody Blanket, Cotton blanket - control group
- Volunteers
- 60 people
- Sponsor
- Aalborg University Hospital
Diabetes Insipidus, Neurohypophyseal, Copeptin Blood Levels
The Trend of Copeptin Levels and Its Clinical Value for Postoperative CDI in Pediatric Patients After NSI in ICU
Central diabetes insipidus (CDI),a disease caused by the decrease of AVP (a hormone involved in the control of water-electrolyte balance ) secretion and characerized by polyuria, is a common complication after neurosurgerical…
- Conditions
- Diabetes Insipidus, Neurohypophyseal, Copeptin Blood Levels, Copeptin, Neurosurgical Intervention
- Trial name
- NCT06742060
- Testing
- serum copeptin levels
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Children's Hospital of Fudan University
Deep Vein Thrombosis
Incidence of Venous Thromboembolism in Children Undergoing Elective Neurosurgical Procedures
The purpose of this study is to determine how frequently children undergoing elective neurosurgical procedures develop blood clots in the deep veins of the legs while hospitalized.
- Trial name
- NCT02037607
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Neuro-surgery, Brain Tumor
Risk Factors of Complications Regarding Patients Undergoing Brain Tumour Neuro-surgery (Cranioscore).
Patients undergoing a brain tumour neurosurgery with craniotomy may present rare but lifethreatening post-operative complications.
- Conditions
- Neuro-surgery, Brain Tumor, Post-operative Complications, Neuro-ICU Stay
- Trial name
- Cranioscore (NCT01801813)
- Testing
- Collecting pre-operative, per-operative data, neuro-radiological data and post-operative neuro-surgery complications
- Where
- France
- Volunteers
- 795 people
- Sponsor
- Nantes University Hospital
Minor Head Injury
The Value of the Canadian CT Head Rule and the New Orleans Criteria in Minor Head Trauma
The New Orleans Criteria (NOC) and the Canadian CT Head Rules (CCHR) have been developed to decrease the number of normal computed tomography (CT) in mild head injury (MHI).
- Trial name
- NCT01619943
- Testing
- no intervention
- Where
- 3 sites in Tunisia
- Volunteers
- 1,600 people
- Sponsor
- University of Monastir
Traumatic Brain Injury With Prolonged Loss of Consciousness
A Trial to Determine the Feasibility and Effectiveness of Early Multisensory Stimulation Intervention in Patients in the Trauma-Neurosurgical Intensive Care Unit (TNICU) Following Severe Acquired Brain Injury
St. Michael's Hospital (SMH) provides service to individuals with some of the most severe brain injuries and intensive care needs in Canada.
- Trial name
- NCT02589223
- Testing
- Multisensory Stimulation, Control
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Unity Health Toronto
Fluid Responsiveness
Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery
The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children.
- Trial name
- NCT01364103
- Testing
- volume expansion
- Where
- 2 sites in South Korea
- Volunteers
- 33 people
- Sponsor
- Seoul National University Hospital
Anticoagulant-induced Bleeding, Intracranial Hemorrhages
Anticoagulant-associated Intracranial Hemorrhage
Oral anticoagulant therapy, including factors Xa and 2a inhibitors has become more popular in recent years due to its efficacy and convenience in preventing thrombotic events and reducing the risk for stroke in patients with rosk…
- Trial name
- AAIHINNN (NCT06168838)
- Testing
- Anticoagulant
- Where
- Mexico
- Volunteers
- 1,200 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Traumatic Brain Injury, Mild Traumatic Brain Injury
Score Predicting Lesion Development on CT Following Mild TBI
Mild traumatic brain injury (mTBI) is one of the most common reasons behind emergency department (ED) visits. A small portion of mTBI patients will develop an intracranial lesion that might require neurosurgical intervention.
- Trial name
- SELECT-TBI (NCT04995068)
- Testing
- Head CT to determine presence of traumatic intracranial lesion
- Where
- Sweden
- Volunteers
- 20,000 people
- Sponsor
- Karolinska Institutet
Epilepsy
An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy
The overall goal of this project is to better understand the micro-physiology of human epilepsy and cognition using the intracranial electroencephalogram (iEEG), electrical brain stimulation, functional magnetic resonance imaging…
- Trial name
- NCT00859794
- Testing
- fMRI, Neuropsychological Testing, Additional electrode implantation
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Northwell Health