Clinical trials: New Technologies
Pediatric Asthma
School-Based Telemedicine Enhanced Asthma Management
This project aims to improve guideline-based asthma care using enhanced communication and screening tools, telemedicine and directly observed therapy of preventive medications in city schools.
- Trial name
- SB-TEAM (NCT01650844)
- Testing
- School-Based Telemedicine Enhanced Asthma Management, Enhanced Usual Care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Rochester
Nonalcoholic Fatty Liver Disease, Metabolic-associated Fatty Liver Disease
To Explore the Value of New MR Technology in Non-invasive Quantitative Assessment of Systemic Metabolism, Disease Status and Prognosis in Patients With Metabolic-Associated Fatty Liver Disease
The purpose of this study is to explore the value of new MR technology in assessing the systemic metabolism, disease status, and prognostic risk of metabolism-related fatty liver disease.
- Trial name
- NCT07149571
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Upper Respiratory Infection, Lower Resp Tract Infection
Holistic Approach Supporting the Uptake of Innovative Diagnostic Technologies for Respiratory Infections
This observational diagnostic validation study aims to evaluate the clinical performance of novel lateral flow and microfluidic-based technologies for the detection of upper and lower respiratory tract infections in children and…
- Trial name
- HOLICARE (NCT07651865)
- Where
- 3 sites in Ethiopia, Senegal and 1 more
- Volunteers
- 1,765 people
- Sponsor
- Karolinska Institutet
Low-Risk Pregnant Women at Full-Term Gestation, Healthy Fetal Population
Advancing Early Bone Health: New Frontiers for Osteoporosis Prevention
All factors that influence the peak bone mass achieved at skeletal maturity are important in determining an individual's risk of developing osteoporosis later in life.
- Conditions
- Low-Risk Pregnant Women at Full-Term Gestation, Healthy Fetal Population, Healthy Neonatal Population
- Trial name
- REMS-BONE (NCT06750523)
- Testing
- Cord blood sampling, urine sampling, Life style questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Parma
Developmental Disability, Intellectual Disability
Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort
The purpose of this research use only (RUO) study is to detect genomic structural variants (SVs) in human DNA by Optical Genome Mapping (OGM) using the Bionano Genomics Saphyr system.
- Conditions
- Developmental Disability, Intellectual Disability, Autism Spectrum Disorder, Congenital Anomaly
- Trial name
- NCT05295277
- Testing
- Standard of care genetic testing group
- Where
- 8 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Bionano Genomics
Vitamin A Deficiency
Dietary Vitamin A Requirement in Chinese Children and the New Technology of Dietary Assessment
Vitamin A deficiency remains a major public health problem in developing country worldwide. Young Children are considered to be at greatest risk of deficiency.
- Trial name
- NCT01559766
- Where
- China
- Volunteers
- 403 people
- Sponsor
- Huazhong University of Science and Technology
Learning Disabilities
Action Medical Research
Learning disability affects 3% of the population. Severe types of learning disability are more likely to have an underlying genetic cause but diagnosis is difficult because many different genetic abnormalities may be involved.
- Trial name
- NCT02227381
- Where
- United Kingdom
- Volunteers
- 119 people
- Sponsor
- Manchester University NHS Foundation Trust
Acute Diarrhea, Acute Respiratory Infection
Improving Nighttime Access to Care and Treatment (Part 2)
Children in resource-limited settings who develop illness at night are often isolated from pre-emergency care, resulting in progression to an emergency because families are forced to wait until morning to seek care.
- Conditions
- Acute Diarrhea, Acute Respiratory Infection, Acute Febrile Illness
- Trial name
- INACT2 (NCT03943654)
- Testing
- MotoMeds Healthline- illness assessment and treatment recommendation for non-emergent cases by telephone
- Where
- Haiti
- Volunteers
- 391 people
- Sponsor
- University of Florida
Adolescent Behavior, Physical Activity
Adolescents' Health Through Mobile Apps, Wearables, and a Gamified TAC ( ActivA-App )
A primary factor in preventing diseases in adulthood, as well as overweight and obesity, is the promotion of physical activity from childhood and adolescence.
- Conditions
- Adolescent Behavior, Physical Activity, New Technologies
- Trial name
- ActivA-App (NCT06140225)
- Testing
- "PACER" Application, "MapMyWalk" Application, "Strava" Application
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Overweight and Obesity, Child Obesity
Fruit and Vegetable Products Enriched With Fibre From Potato Starch With Prebiotic Properties for Children and Youth
The main goal of the project is to test fruit and vegetable mousse, with the addition of a fiber preparation made of potato starch with prebiotic properties, on selected clinical, metabolic and immunological parameters in…
- Conditions
- Overweight and Obesity, Child Obesity, Hypertension, NAFLD
- Trial name
- NCT05140070
- Testing
- Vegetable and fruit mousse enriched with a fiber preparation from potato starch with prebiotic properties, Vegetable and fruit mousse, Dietary and physical activity counselling
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Children's Memorial Health Institute, Poland
Childhood Obesity
"Mandometer®" Study for Managing Childhood Obesity
We run a successful clinic in Bristol for children with severe obesity who already demonstrate many features to suggest they are at increased risk of early diabetes and heart disease.
- Trial name
- NCT00407420
- Testing
- Mandometer, Lifestyle
- Where
- United Kingdom
- Volunteers
- 106 people
- Sponsor
- University of Bristol
Autism Spectrum Disorder, Repetitive Compulsive Behavior
Family-Implemented Treatment on the Behavioral Inflexibility of Children With Autism
The overall goal of this project is to determine whether a new form of family-based treatment for repetitive and inflexible behaviors, delivered using videoconferencing technology, can counter any negative effects of those…
- Trial name
- FITBI (NCT05125003)
- Testing
- FITBI, Parental Education
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Adherence, Patient, Pre-Exposure Prophylaxis
mHealth Technologies to Enhance PrEP Adherence Among Thai MSM
This study aims to: 1) adapt the theory-based P3 (Prepared, Protected, emPowered) app designed to improve pre-exposure prophylaxis (PrEP) adherence, retention in PrEP clinical care, and PrEP persistence among young gay, bisexual…
- Conditions
- Adherence, Patient, Pre-Exposure Prophylaxis, HIV/AIDS
- Trial name
- P3-T (NCT04413708)
- Testing
- P3-T PrEP Adherence App
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duke University
Type 1 Diabetes Mellitus
The Skin Barrier in Users of Diabetes Devices
Diabetes technology (insulin pumps and continuous glucose monitoring) have become standard of care in children with type 1 diabetes.
- Trial name
- StenoLin (NCT06856954)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Jannet Svensson
Depression
New Technologies for Cognitive Behavior Therapy (CBT) Treatment of Adolescent Depression
The goal of this study is to examine the use of new technologies in disseminating and improving CBT treatment for adolescent depression.
- Trial name
- NCT01868867
- Testing
- Intervention
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Center for Psychological Consultation
Knotting Methods, Single-port Laparoscopic Surgery
Application of Spaghetti Knotting Technology in Single-hole Laparoscopic Suturing Instructional Program on the Basis of Multidirectional Stitching Technology.
The surgeon's knot-tying technique plays a crucial role in the recovery of patients after single-port laparoscopy. Knot tying is very challenging in minimally invasive surgery and is a critical skill in advanced surgery.
- Trial name
- NCT05762575
- Testing
- knotting methods
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Infections, Respiratory, Respiratory Tract Infections
Novel Technologies for Respiratory Virus Identification
Current virus detection methods often take significant time or can be limited in sensitivity, specificity or cost. There is therefore a need for diagnostic methods that are simple to use, sensitive, rapid and inexpensive.
- Trial name
- ResVir (NCT05661032)
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Portsmouth Hospitals NHS Trust