Clinical trials: Nicotine Dependence Tobacco Product
Alcohol Abuse, Cannabis Abuse
Trial of Computerized SBI to Reduce Teen Alcohol Use
The goal of this project is to test the effectiveness of a computer-facilitated alcohol screening and brief intervention (c-ASBI) system for 12- to 18-year-old primary care patients in a multi-site, randomized comparative…
- Conditions
- Alcohol Abuse, Cannabis Abuse, Nicotine Dependence
- Trial name
- NCT01784627
- Testing
- c-ASBI
- Where
- 6 sites in United States
- Sponsor
- Boston Children's Hospital
Nicotine Dependence
Reactions to Reduced Nicotine Cigarettes in Young Adult Low-Frequency Smokers
The purpose of this study is to evaluate reactions to, and choices to self-administer, cigarette smoke with varying nicotine content among low-frequency, non-dependent adolescent/young adult smokers between the ages of 15-25…
- Trial name
- NicRed (NCT02989038)
- Testing
- Very Low Nicotine Content Cigarettes, Intermediate Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Duke University
Nicotine Dependence
Evaluation of Very Low Nicotine Content Cigarettes in Adolescent Smokers
The purpose of this study is to determine how reducing the level of nicotine in cigarettes may affect adolescent smoking behavior.
- Trial name
- NCT02587312
- Testing
- Very low nicotine content cigarettes, Standard nicotine content cigarettes
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Brown University
Vaping
Social Media Intervention to Stop Nicotine and Cannabis Vaping Among Adolescents
Social media based intervention to support teens in their efforts to quit vaping.
- Trial name
- NCT04707911
- Testing
- Social Media Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiovascular Disease, Essential Hypertension
The Northwest Coalition for Primary Care Practice Support
The purpose of this project is to build capacity for quality improvement (QI) in small primary care practices across Washington, Oregon and Idaho by improving risk factors for heart attacks such as blood pressure, cholesterol and…
- Conditions
- Cardiovascular Disease, Essential Hypertension, Nicotine Dependence, Hyperlipidemia
- Trial name
- H2N (NCT02839382)
- Testing
- Coaching, Educational Outreach, Site Visits
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Kaiser Permanente
Tobacco Dependence, Schizophrenia
The Pharmacogenetic Study , Readiness to Change, and Pharmacological Intervention for Smoking Cessation in Schizophrenia
Cigarette smoking represents a major health problem for patients suffering from schizophrenia. Compared to the general population, schizophrenic patients are significantly more likely to be addicted to nicotine.
- Trial name
- PSIAARP (NCT00495352)
- Testing
- Hihg-doseNRT, Low-dose NRT, bupropion
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- Yu-Li Hospital
Tobacco Use Behavior, Nicotine Dependence Tobacco Product
§SMOKE Nicotine and Tobacco Youth Cohort
The §SMOKE Cohort Study aims to improve understanding of tobacco and nicotine use among adolescents and young adults in Denmark.
- Conditions
- Tobacco Use Behavior, Nicotine Dependence Tobacco Product, E-Cigarette Use, Smoking ( Cigarette)
- Trial name
- NCT07910331
- Where
- Denmark
- Volunteers
- 10,000 people
- Sponsor
- University of Southern Denmark
Nicotine Dependence
Extended Cessation Treatment for Teen Smokers
This study is designed to test the efficacy of an extended smoking cessation program for teen smokers. We hypothesize that teen smokers randomized to extended treatment will have a higher abstinence rate at 52 week follow-up than…
- Trial name
- Nicoteens (NCT00459953)
- Testing
- Extended treatment
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Stanford University
Smoking
Youth Smoking Cessation: Therapy +/- "The Patch"
Reducing tobacco use by adolescents is a national health priority. In recent polls, most adolescent smokers reported having tried unsuccessfully to quit.
- Trial name
- NCT00631020
- Testing
- CBME, Optional NRT
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Drug Abuse, Alcohol Abuse
Trial of Computerized MET for Adolescent Substance Use
The purpose of this study is to test the effects of a computerized, self-directed Motivational Enhancement Therapy program for adolescent substance use (iMET), in comparison to clinician-delivered MET and Treatment As Usual…
- Conditions
- Drug Abuse, Alcohol Abuse, Nicotine Dependence
- Trial name
- NCT01784653
- Testing
- iMET, MET
- Where
- United States
- Sponsor
- Boston Children's Hospital
Cancer, Smoking
Improving Tobacco Treatment Rates for Outpatient Cancer Patients Who Smoke
The main purpose of this research study is to evaluate the effectiveness of "nudges" to clinicians, to patients, or to both in increasing Tobacco Use Treatment Service (TUTS) referral and engagement; and to explore clinician…
- Conditions
- Cancer, Smoking, Tobacco Use, Nicotine Dependence
- Trial name
- SPP1 (NCT04737031)
- Testing
- Clinician Nudge, Patient Nudge
- Where
- 3 sites in United States
- Volunteers
- 2,146 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Nicotine Dependence, Substance Use Disorders
Healthy People Initiative (HPI)
Addictions do not occur in isolation. Tackling addictions requires addressing social determinants such as isolation, homelessness, marginalization, and unemployment.
- Trial name
- HPI (NCT03506867)
- Testing
- Life skills, training, education and work/volunteer opportunities, Usual Care
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Asthma, Tobacco
Efficacy of School-Based, Peer-Led Asthma and Smoking Prevention Program on CO1 Levels and Smoking Behavior Among Early Adolescents in Jordan
Study Hypotheses: 1. adolescents in intervention schools who are given Triple A program plus ASP will show more awareness in regards to cigarettee smoking health effects and less nicotine dependencethan those in the control…
- Conditions
- Asthma, Tobacco, Waterpipe, Cigarettes
- Trial name
- TAJPlus (NCT01938976)
- Testing
- TAJ Plus (Adolescent Asthma Action in Jordan) Plus the added class smoke free pledge
- Volunteers
- 815 people
- Sponsor
- University of Technology, Sydney
Nicotine Dependence
Varenicline for Adolescent Smoking Cessation
This is a placebo-controlled smoking cessation treatment study for adolescents ages 14-21. After assessment and inclusion into the study, participants will be randomized to receive a 12-week double blind course of varenicline or…
- Trial name
- NCT01509547
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Medical University of South Carolina
Nicotine Dependence, Smoking Cessation
Nicotine Replacement for Smoking Cessation During Pregnancy
This is a clinical trial to determine if the nicotine inhaler in combination with counseling will help pregnant women quit smoking, and whether it is safe when compared to placebo (an inactive inhaler).
- Trial name
- NCT01656733
- Testing
- Nicotrol Inhaler
- Where
- 2 sites in United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- UConn Health
Vaping, Vaping Teens
Behavioral Intervention for Youth to Promote Vaping Cessation
This study will test the hypothesis that the QuitVaping (QV) intervention and additional texting support will improve nicotine abstinence rates in adolescents as compared to Enhanced Usual Care (EUC: education about nicotine…
- Conditions
- Vaping, Vaping Teens, Nicotine Dependence
- Trial name
- VIA (NCT06765291)
- Testing
- QuitVaping, This is Quitting (TIQ)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
HIV, Smoking
A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research
The objective of this trial is to evaluate the effectiveness of "nudges" to clinicians, patients, or both in increasing referral to, and engagement with, tobacco use treatment services (TUTS) for HIV patients versus usual care.
- Conditions
- HIV, Smoking, Tobacco Use, Nicotine Dependence
- Trial name
- NCT05852860
- Testing
- Clinician Nudge, Patient Nudge
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Nicotine Dependence, Cigarettes
AI-Enhanced App-based Intervention for Adolescent E-cigarette Cessation
The goal of this quasi-experimental study is to test if a smartphone app can help adolescents aged 14-20 quit e-cigarettes. The main questions it aims to answer are: Can the app help adolescents manage cravings and increase their…
- Trial name
- NCT06965296
- Testing
- AI-enhanced smartphone app, AI-enhanced smartphone app, but with delayed access
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- State University of New York at Buffalo
Nicotine Dependence, Nicotine Use Disorder
Combined Pharmaco/Behavior Therapy in Adolescent Smokers
In the current proposal, we intend to study the efficacy of bupropion SR with or without combined contingency management (CM) among adolescent cigarette smokers.
- Trial name
- NCT00330187
- Testing
- Bupropion SR, Contingency Management
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Use Cessation, Tobacco Use Disorder
Effectiveness of Bupropion for Treating Nicotine Dependence in Young People
Little is known about the best ways to help young people stop smoking. Bupropion (a medication marketed as Wellbutrin or Zyban) has proved helpful in treating adult smokers.
- Trial name
- NCT00129272
- Testing
- Bupropion-SR
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- National Institute on Drug Abuse (NIDA)