Clinical trials: Nicotine Use Disorder
Smoking, Tobacco Use Disorder
Examining a New Biomarker of Nicotine Use Among Pregnant Women Who Participated in the New England SCRIPT
Smoking during pregnancy is the single most preventable cause of illness and death among mothers and infants. Because of the stigma associated with tobacco use during pregnancy, pregnant women are less likely to disclose their…
- Trial name
- SCRIPT (NCT00519766)
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Glucose-Galactose Malabsorption, Enteropathy
Labelled Carbon Sucrose Breath Test (13C-SBT) as a Marker of Environmental Enteropathy
Linear growth failure, a manifestation of chronic undernutrition in early childhood, is a recalcitrant problem in resource constrained settings.
- Conditions
- Glucose-Galactose Malabsorption, Enteropathy, Malnutrition, Child, Intestinal Permeability
- Trial name
- SBT4EE (NCT04109352)
- Where
- 9 sites in Australia, Bangladesh and 6 more
- Volunteers
- 600 people
- Sponsor
- University of Virginia
Nicotine Dependence
Enhancing a High School Based Smoking Cessation Program
The purpose of this study is to examine the the efficacy of adjunctive nicotine replacement therapy when used in combination with the contingency management (CM) + cognitive behavioral therapy intervention.
- Trial name
- NCT01145001
- Testing
- Cognitive Behavioural Therapy, Contingency Management, Nicotine Transdermal Patch
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Yale University
Tobacco Dependence
Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Dependence
The purpose of this study is to test the safety, tolerability, compliance and efficacy of two different forms of nicotine replacement therapy (NRT) (the nicotine transdermal patch and the nicotine gum) in a nicotine-dependent…
- Trial name
- NCT01208935
- Testing
- Nicotine Patch, Nicotine Gum
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cigarette Smoking, Nicotine Dependence
School Nurse-Delivered Smoking Cessation Intervention
The purpose of this study is to conduct a randomized controlled school-based trial to evaluate the effectiveness of a four-session school nurse-delivered smoking cessation intervention in increasing abstinence rates among high…
- Trial name
- NCT00682474
- Testing
- Counseling Intervention, Information Intervention
- Where
- United States
- Volunteers
- 1,058 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Cigarette Smoking-Related Carcinoma
Electronic Cigarette Use During Pregnancy
Aim 1: To compare the overall toxicant exposure in pregnant women who use electronic cigarettes (e-cigs, vapor, e-liquid, e-juice, vape, vaping devices) compared to women who smoke conventional cigarettes. Aim 2.
- Trial name
- NCT03480373
- Where
- 6 sites in United States
- Volunteers
- 182 people
- Sponsor
- UConn Health
Nicotine Dependence
Prize Reinforcement for Smoking Cessation
Nicotine dependence is prevalent in society, cigarette smoking is associated with several known health risks, and most dependent individuals find it very difficult to stop smoking cigarettes.
- Trial name
- NCT00865254
- Testing
- Standard Treatment, Traditional Contingency Management, Early Enhanced Contingency Management
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Cancer, Tobacco Use
Improving Tobacco Treatment Rates for Cancer Patients Who Smoke
The research objective is to identify a simple, pragmatic, innovative way of enhancing Tobacco Use Treatment (TUT) rates within oncology.
- Conditions
- Cancer, Tobacco Use, Smoking, Nicotine Dependence
- Trial name
- NCT04738643
- Testing
- Tobacco Use Treatment Service and Varenicline Management
- Where
- 2 sites in United States
- Volunteers
- 685 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Nicotine Dependence
Effects of Smoking Cues on Tobacco Craving Responses and the Reinforcing Efficacy of Cigarettes in Adolescent Smokers
Background: Multiple social, psychological, and environmental factors contribute to adolescents' use of cigarettes. Environmental smoking cues have been shown to play an important role in the maintenance of nicotine addiction and…
- Trial name
- NCT01148355
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Pregnancy in Adolescence
Teen motHers' ReproductIve and behaVioral Health intErvention in Barbados
The goal of this clinical trial is to learn if an integrated care program can help improve overall health and prevent repeat pregnancy in teen mothers in Barbados.
- Trial name
- THRIVE (NCT07149948)
- Testing
- THRIVE Integrated Care Program
- Where
- Barbados
- Volunteers
- 50 people
- Sponsor
- Hada Fongha Ieong, PhD
Smoking
Korean Youth Smoking Cessation Study
Cigarette smoking remains the leading preventable cause of morbidity and mortality in the United States. In Los Angeles, rates of morbidities due to cigarette smoking follow prevalence.
- Trial name
- NCT02021175
- Testing
- Tailored CBME Therapy via Technology, Standard of Care
- Where
- United States
- Sponsor
- University of California, Los Angeles
Nicotine Dependence
Adjunctive Mood Management for Telephone-based Smoking Cessation
Smoking is the leading cause of morbidity and mortality in the U.S. Interventions that increase successful quit attempts among depressed smokers with chronic medical illnesses are particularly important for the VA healthcare…
- Trial name
- NCT02500589
- Testing
- Behavioral mood management, Health education
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- VA Office of Research and Development
Vaping, Vaping Cessation
Social Media Support Groups for Adolescent Vaping Cessation
The purpose of this study is to pilot test feasibility and acceptability of the Quit the Hit Toolkit, a social media-based nicotine vaping cessation program for adolescents and young adults, adapted for use in community settings.
- Conditions
- Vaping, Vaping Cessation, Nicotine Dependence
- Trial name
- NCT07540780
- Testing
- Social Media Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Nicotine Dependence
Bupropion Treatment for Youth Smoking Cessation
The purpose of this study is to 1) evaluate the safety and efficacy of two doses of bupropion SR (150mg/day and 300mg/day) when compared to placebo, as an aid to smoking cessation in adolescents and 2) to examine which factors…
- Trial name
- NCT00344695
- Testing
- bupropion SR
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Smoking, Nicotine Dependence
Project 1: Evaluating EHR-Based Health System Modifications for the Chronic Care of Smoking
Smoking is the leading preventable cause of cancer mortality in the US. Despite its profound health and economic costs, smoking treatment is infrequently provided in healthcare settings, and when provided, it is not sufficiently…
- Conditions
- Smoking, Nicotine Dependence, Electronic Health Records, Translational Research
- Trial name
- EHR Project (NCT02358330)
- Testing
- EHR Enhanced Clinic Intervention
- Where
- United States
- Volunteers
- 28,095 people
- Sponsor
- University of Wisconsin, Madison
E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention
A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents
This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school…
- Conditions
- E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
- Trial name
- NCT07460622
- Testing
- Virtual Reality E-Cigarette Prevention Program
- Where
- United States
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- Yale University
Nicotine Use Disorder, Tobacco Use Disorder
Evaluation of the Addictive Potential of E-Cigarettes
This study will examine the subject matter from a neurobiological and a neuropsychological vantage point to ascertain whether the e-cigarette is potentially as addictive as the traditional tobacco cigarette.
- Trial name
- EVAPE (NCT04772014)
- Where
- Germany
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Tobacco Use Disorder
Incentive Programs for Female Substance Abusers Who Smoke - 3
The purpose of this study is to examine the effects of incentive programs for the treatment of nicotine dependence in women who have problems with substance dependence.
- Trial name
- NCT00064922
- Testing
- Behavior Therapy
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Tobacco Use Disorder
Tobacco Approach Avoidance Training for Adolescent Smokers-2
This is a two part study. In Study 2, smokers who want to quit smoking will participate in a 4 week smoking cessation program combining weekly cognitive behavioral therapy (CBT) with weekly regular-AAT or placebo-AAT training.
- Trial name
- AAT-2 (NCT01625637)
- Testing
- AAT-experiment
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Yale University