Clinical trials: Normal Skin
Mesothelioma, Lung Neoplasms
Chest Wall Motion Analysis in Disease
Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest.
- Conditions
- Mesothelioma, Lung Neoplasms, Surgery, Cystic Fibrosis
- Trial name
- CWM (NCT02958683)
- Testing
- Chest wall motion analysis
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Heart of England NHS Trust
Atopic Dermatitis
Impact of Vitamin D Supplementation on Severity of Pediatric Atopic Dermatitis
The purpose of this study is to determine whether oral vitamin D supplementation improves the clinical severity of atopic dermatitis in children.
- Trial name
- VIDATOPIC (NCT01996423)
- Testing
- Vitamin D3
- Where
- Chile
- Volunteers
- 101 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Rheumatoid Arthritis, Spondyloarthritis
Pregnancy and Medically Assisted Conception in Rare Diseases
Rare diseases frequently affect women of childbearing age. Pregnancy in these women has become less rare, but remains associated with high levels of complications.
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Psoriatic Arthritis, Systemic Lupus Erythematosus
- Trial name
- EGR2 (NCT02450396)
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetic Foot, Type 2 Diabetes Mellitus With Established Diabetic Nephropathy
The Effectiveness of Improving Self-care After Counseling for the Diabetics Mellitus Foots Around Chiayi Region
Objectives: Preventing diabetic foot problems (DFP) and associated consequences, such as amputation, is a critical in rural regions.
- Trial name
- NCT01299246
- Testing
- Michigan Neuropathy Screening Instrument
- Where
- Taiwan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Leishmaniasis
Treatment of Leishmaniasis With Impavido® (Miltefosine): Higher-Weight Patient Registry
This study is a prospective observational study in which patients undergoing treatment for leishmaniasis with miltefosine (Impavido) in the US and who weigh > 75 kg can volunteer to provide information about their clinical…
- Trial name
- NCT02429505
- Testing
- Miltefosine
- Where
- United States
- Sponsor
- Knight Therapeutics (USA) Inc
Breast Cancer
Effectiveness of Peer Support on Quality of Life in Recently Diagnosed Breast Cancer Patients
This study examines effectiveness of peer support of breast cancer patients. Half of the participants received peer support via telephone in addition to usual care and another half are give the usual care only.
- Trial name
- NCT03394742
- Testing
- Peer support
- Where
- Finland
- Volunteers
- 260 people
- Sponsor
- University of Jyvaskyla
Multimorbidity, Comorbidity
Use of a Hypercaloric and Hyperprotein Supplement Enriched with Immunonutrients in Multi-pathological Malnourished Patients to Improve the Incidence and Prevalence of Pressure Sores
The goal of this study is to evaluate the efficacy of a hypercaloric, hyperproteic enteral formula enriched with immunonutrients in preventing and treating pressure injuries in hospitalized malnourished patients.
- Conditions
- Multimorbidity, Comorbidity, Malnutrition, Pressure Ulcer Prevention
- Trial name
- NCT06726486
- Testing
- Atémpero, Control (Standard treatment)
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- University of Cadiz
Sjogren's Syndrome, Salivary Gland
Evaluation of Salivary Gland Dysfunction
This study will evaluate patients with complaints of dry mouth to determine the cause and severity of their salivary gland dysfunction and their possible eligibility for other NIDCR protocols.
- Trial name
- NCT00001196
- Where
- United States
- Volunteers
- 1,740 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Kawasaki Disease
Infliximab for Kawasaki Disease Patients Resistant to IVIG : a Multicentre, Prospective, Randomised Trial
The objective of this study is to investigate the effect of infliximab to the children who don't respond to the first dose of intravenous immunoglobulin (IVIG) (2g/kg) in Kawasaki disease.
- Trial name
- NCT02298062
- Testing
- Infliximab, IVIG
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fudan University
Atopic Dermatitis
Vitamin D Supplementation in Childhood Atopic Dermatitis
The goal of this clinical trial is to investigate the therapeutic role of vitamin D supplementation in a subset of patients with atopic dermatitis (AD): children with disease onset or worsening in the winter.
- Trial name
- NCT00879424
- Testing
- cholecalciferol (vitamin D)
- Where
- Mongolia
- Volunteers
- 107 people
- Sponsor
- Massachusetts General Hospital
Melanoma, Spitzoid Melanoma
Identification of Risk Factors, Exposomics and Genetic Susceptibility of Melanoma in Children, Adolescents and Young Adults
The primary objective of this study is the identification of environmental and genetic factors involved in the risk and progression of melanoma in children, adolescents and young adults (CAYA).
- Conditions
- Melanoma, Spitzoid Melanoma, Congenital Nevi
- Trial name
- ExpoMel (NCT06680323)
- Where
- 6 sites in Germany, Italy and 3 more
- Volunteers
- 200 people
- Sponsor
- University Hospital Tuebingen
Williams Syndrome, Cardiovascular Disease
WS-SAVE Study (Williams Syndrome Skin and Vessel Elasticity Study)
Background: Williams Syndrome (WS) is a genetic disorder. People with WS have less of a protein that allows parts of the body to stretch than other individuals.
- Conditions
- Williams Syndrome, Cardiovascular Disease, Multisystem Developmental Disorder, Elastin Gene Deletion
- Trial name
- NCT02692846
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Breast Cancer
Studying Tumor Tissue Samples From Patients With Early-Stage Breast Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00899639
- Sponsor
- Rutgers, The State University of New Jersey
Breast Cancer
A Real-world Efficacy and Safety Study of Amlotinib for HER2-negative Advanced Breast Cancer
This study analyses the efficacy and safety of amlotinib as a study drug in the treatment of HER-2 negative advanced breast cancer in the real world, including the number of treatment lines, monotherapy, combination therapy, and…
- Trial name
- NCT06340165
- Testing
- Anlotinib
- Where
- China
- Volunteers
- 153 people
- Sponsor
- The First Hospital of Jilin University
Fusariosis
Markers of Infection and Resistance in Invasive Fusariosis
In recent decades, invasive fusarioses have been emerging fungal pathologies with high mortality. The prognosis depends on the speed of the diagnosis, but currently biological diagnosis is mainly based on fungal culture, no…
- Trial name
- FUSIMIR (NCT04937751)
- Testing
- biomarkers
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Kawasaki Disease, Pilot Study
Model-informed Dose Optimization for Rivaroxaban in Children With Giant Coronary Artery Aneurysm After Kawasaki Disease
Based on a population pharmacokinetic model-based dose optimization study, a 15 mg-equivalent, age-, and bodyweight-adjusted dosing regimen for Chinese children with giant coronary artery aneurysms after Kawasaki disease was…
- Conditions
- Kawasaki Disease, Pilot Study, Coronary Artery Aneurysm, Rivaroxaban
- Trial name
- NCT06978439
- Testing
- Rivaroxaban (Xarelto)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Fudan University
Vitiligo
HI-Light Pilot Trial for Vitiligo: Hand Held NB-UVB for Early or Focal Vitiligo at Home
This study is a small pilot randomised controlled trial (RCT) comparing hand-held NB-UVB light devices with placebo devices. These devices will be used by the participants to treat their vitiligo at home for a period of four…
- Trial name
- HI-Light (NCT01478945)
- Testing
- 311 nm NB-UVB light
- Where
- 2 sites in United Kingdom
- Volunteers
- 29 people
- Sponsor
- University of Nottingham
Acne Vulgaris
Impact of Isotretinoin in Different Doses on Quality of Life
The Cardiff Acne Disability Index is a short five-item questionnaire derived from the longer Acne Disability Index.It is designed for use in teenagers and young adults with acne.
- Trial name
- NCT05316675
- Testing
- Isotretinoin
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Mucocutaneous Lymph Node Syndrome
Methylprednisolone Pulse Therapy for Coronary Artery Dilatation or Aneurysm Formation in Kawasaki Disease
In this study, the investigator plan to prescribe Methylprednisolone pulse therapy in Kawasaki disease patients with coronary artery lesions or aneurysm formation beyond acute stage to investigate the role for vasculitis of KD or…
- Trial name
- NCT04509219
- Testing
- Methylprednisolone Injection
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Chang Gung Memorial Hospital
Systemic Lupus Erythematosus
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 on Children With Rheumatic Diseases
The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with rheumatic diseases (Systemic Lupus Erythematosus, Primary Sjögren Syndrome, Juvenile Idiopathic Arthritis).
- Trial name
- SLE，pSS，JIA (NCT04397107)
- Testing
- IL-2
- Where
- China
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
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